Careers at Adaptive

Who is Adaptive?

Adaptive Biotechnologies Corporation is a development stage biotechnology company that utilizes its proprietary immune profiling technology to discover, develop, and commercialize oncology diagnostics. The Company leverages advances in next generation sequencing (“NGS”) to profile T-Cell and B-Cell Receptors (“TCRs” and “BCRs”). This breakthrough enables in-depth characterization of the immune system, which is the primary defense against cancer. By incorporating immunosequencing into clinical care, Adaptive can enhance the diagnosis, prognosis, and monitoring of cancer patients.

The Company’s first clinical application, clonoSEQTM, is for monitoring Minimal Residual Disease (“MRD”) in blood-based cancers. The Company recently launched clonoSEQ as a CLIA certified Laboratory Developed Test (“LDT”) in the second quarter of 2013. Improving the ability to accurately detect and track residual disease at a molecular level affords clinicians the potential to detect relapse earlier and improve patient care. Adaptive is currently validating additional oncology diagnostics to quantify the presence and clonality of Tumor Infiltrating Lymphocytes (“TIL”) and to create a reliable measure of “immunocompetency” to predict or monitor response to cancer treatments that directly alter the host immune system. Adaptive incubates and validates potential clinical products by offering fee-for-service access to its proprietary immune profiling sequencing technology under the brand name immunoSEQTM.

Why work at Adaptive?

When you join Adaptive Biotechnologies, you’ll be challenged, you’ll be inspired, and you’ll be proud to be part of a team making a real difference in the lives of us all. No matter what your position is within the company, you’ll find a culture that is diverse, fun, team-oriented, and where your bright ideas are truly heard.

We offer our valued employees a fantastic benefits package, training, and a work-life balance that few companies can match. We also offer a real career path where you’ll be learning and growing the moment you start working here.

Current Openings

Click on job titles for complete posting information.

SOFTWARE ENGINEER SPECIALIZING IN LIMS
OVERVIEW
Adaptive is currently seeking a full-time Software Engineer specializing in Laboratory Information Management Systems (LIMS) to join our growing team in Seattle, WA. This position will be responsible for interacting with laboratory staff to define, design and implement sample and data tracking processes using the Genologics Clarity LIMS.This is a great opportunity for an early career software developer or molecular biologist with programming experience to break into the biotechnology/clinical genetics field.

RESPONSIBILITIES

  • Interact directly with laboratory staff to define and/or optimize LIMS processes
  • Design, refactor, implement, test, and support software for LIMS system used by internal clinical and R&D labs.
  • Integrate the LIMS system with laboratory instruments and other software systems.
  • Responsible for all aspects of the software development life cycle, from collecting software requirements from research scientists and lab technicians to supporting your solution in production.
  • Apply Agile software development skills to create software that works in a dynamic environment with changing requirements.
  • Create custom summary reports of laboratory processes and production metrics.

REQUIRED EXPERIENCE

  • 3+ years experience developing Java/Groovy applications.
  • Experience developing software for a scientific laboratory.
  • Experience with RESTful APIs.
  • Experience with gathering abstract and changing requirements from users and ultimately delivering high quality software into production.
  • Experience with relational databases.
  • Able to work independently, but also happy to work with and support fellow team members.

REQUIRED SKILLS

  • Java, Groovy.
  • RESTful APIs, relational databases.
  • Linux.

QUALIFIED CANDIDATES WILL POSSESS

  • Education, training, or experience in biological sciences.
  • Previous experience with LIMS systems – specifically Genologics Life Sciences Software.
  • Laboratory automation.
  • Source control, continuous integration.
  • Direct experience developing for Genologics Geneus/Clarity products.

Salary is commensurate with experience and qualifications. Excellent benefits package including employer paid medical, dental, vision, vacations and holidays. Adaptive Biotechnologies Corp. is proud to be an Equal Opportunity Employer, and offer a smoke and drug free environment.

If you are a bright, career-minded individual we want to hear from you! Please submit your resume and cover letter to careers@adaptivebiotech.com.

BIOINFORMATICS ANALYST
OVERVIEW
Adaptive Biotechnologies Corporation, headquartered in Seattle, WA, is pioneering the field of genomic immunology. The company’s core competency is developing next generation sequencing assays that characterize the adaptive immune system, serving as a platform technology to the research and clinical communities , as well as the biopharmaceutical industry.

Adaptive Biotechnologies Corp. seeks highly qualified applicants for a Bioinformatics Analyst. Adaptive’s proprietary method for sequencing genes relating to the adaptive immune system generates large volumes of data and we are looking for a bioinformatics analyst to work independently and in collaboration with other research scientists to develop new tools in the analysis of large genomic and sequencing data sets.

RESPONSIBILITIES

  • Analyze and process high-volume genomic (immune receptor) sequencing datasets.
  • Design, implement, and test new scripts and tools to analyze and display data.
  • Collaborate with research scientists to provide necessary reports and data, implement appropriate statistical tests.
  • Become familiar with large genomics community software development and statistical analysis projects and implementation of latest analysis algorithms.
  • Perform complex data analysis in support of ad-hoc and standing customer requests.

REQUIRED EXPERIENCE

  • Graduate education (Ph.D.) in computer science, bioinformatics, or related field, with coursework in biology.
  • 4+ years of experience working with a variety of information systems and data analysis.
  • Demonstrated ability to manage, manipulate, and interpret large biological data sets, transforming raw data into finished products.
  • Working knowledge of data analysis and statistical methods used in genomics and bioinformatics.
  • Demonstrated experience in analysis and presentation of data required.
  • Experience in Perl or Java and statistical languages such as R, SAS, or Matlab.
  • Proven critical thinking skills and the ability to consider outcomes when designing analyses.
  • Able to work independently, but also happy to work with and support fellow team members.

QUALIFIED CANDIDATES WILL POSSESS

  • Background in immunology.
  • Strong statistical background.
  • Innovative thinking and strong problem solving skills.
  • Ability to work in a team environment.
  • Strong communication and interpersonal skills, ability to collaborate across disciplines.

Salary is commensurate with experience and qualifications. Excellent benefits package including employer paid medical, dental, vision, vacations and holidays. Adaptive Biotechnologies Corp. is proud to be an Equal Opportunity Employer, and offer a smoke and drug free environment.

If you are a bright, career-minded individual we want to hear from you! Please submit your resume and cover letter to careers@adaptivebiotech.com.

COMPUTATIONAL BIOLOGIST (IMMUNOLOGY)
OVERVIEW
Adaptive Biotechnologies Corp. seeks highly qualified applicants for a Computational Scientist. Adaptive Biotechnologies is an early stage biotechnology company commercializing a patent pending technology to measure vital properties of the human immune system. This is a platform technology with the potential to revolutionize the diagnosis and treatment of major diseases such as cancer, Multiple Sclerosis, and childhood Diabetes.

Adaptive’s proprietary method for sequencing genes relating to the adaptive immune system generates large volumes of data, and we are looking for a computational scientist to work independently and in collaboration with other research scientists in the analysis of large genomic and sequencing data sets. The Computational Scientist would play a critical role in ensuring the ongoing success of research experiments and projects belonging to internal and external customers.

RESPONSIBILITIES

  • Identify opportunities and needs for innovative solutions using specialized high-volume genomic (immune receptor) sequencing datasets
  • Display a high level of critical thinking in cross-functional process analysis and problem resolution for new and existing products.
  • In collaboration with research scientists, develop/acquire scripts and tools to analyze and display data.
  • Interface with research scientists to provide necessary reports and data, implement appropriate statistical tests.
  • Use and support command-line and web-based database applications and analytical tools: evaluate data quality, applications, and function.
  • Become familiar with large genomics community software development and statistical analysis projects and implementation of latest analysis algorithms.
  • Compose and contribute to manuscripts for publication
  • Perform complex data analysis in support of ad-hoc and standing customer requests.
  • Establish good working relationships with internal and external customers.

REQUIREMENTS

  • Graduate education (Ph.D.) in computer science, bioinformatics, or related field, with coursework in molecular biology. Background in immunology a strong plus.
  • 4+ years of experience working with a variety of information systems and data files, including analyzing file structure, and using and creating layouts of large and complex files.
  • Demonstrated ability to manage, manipulate, and interpret large biological data sets, transforming raw data into finished products.
  • Working knowledge of data analysis and statistical methods used in genomics and bioinformatics.
  • Demonstrated experience in analysis and presentation of data required.
  • Excellent cross-platform computing skills, including experience using Linux/Unix Operating Systems, Macintosh OS X and Windows operating systems.
  • Experience in Perl and Java programming as well as statistical languages such as R, SAS, or Matlab.
  • Proven critical thinking skills and the ability to consider outcomes when designing analyses.
  • The ability to be self-motivated and work independently, with minimal supervision, while also working as part of a team environment in a dynamic organization.
  • Strong interpersonal and communication skills, both written and spoken, with a confident and cooperative service-oriented attitude.
  • Ability to read, write, speak and understand English required.

HIGHLY QUALIFIED CANDIDATES WILL POSSESS

  • Strong statistical computer programming, and machine learning experience.
  • Demonstrated independence and critical thinking skills
  • Strong publication record in top tier journals.
  • Laboratory research experience in immunology (preferred), genetics, molecular biology, or biochemistry.
  • Demonstrated experience in DNA or RNA sequence analysis and presentation of results.

Salary is commensurate with experience and qualifications. Excellent benefits package including employer paid medical, dental, vision, vacations and holidays. Adaptive Biotechnologies is proud to be an Equal Opportunity Employer and offer a smoke & drug free environment.

If you are a bright, career-minded individual we want to hear from you! Please submit your resume and cover letter.

To apply: upload your resume here .

Postdoctoral Analyst
OVERVIEW
The company’s proprietary method for sequencing genes relating to the adaptive immune system generates large volumes of data, and Adaptive is looking for a data analyst to work with research scientists in the manipulation and analysis of these large data sets. The data analyst would play a critical role in ensuring the ongoing success of experiments and projects belonging to internal and external customers.

PRIMARY RESPONSIBILITIES

  • Process and analyze specialized high-volume datasets.
  • Perform complex data analysis in support of ad-hoc and standing customer requests.
  • In collaboration with research scientists, develop/acquire scripts and tools to analyze and display data.
  • Interface with research scientists to provide necessary reports and data, implement appropriate statistical tests, and contribute to publications.
  • Use and support command-line and web-based database applications and analytical tools: evaluate data quality, applications, and function.
  • Become familiar with large genomics community software development and statistical analysis projects and implementation of latest analysis algorithms.
  • Establish good working relationships with internal and external customers.

KNOWLEDGE AND SKILL REQUIREMENTS

  • Graduate education (Ph.D. preferred) in computer science, bioinformatics, or related field, with coursework in molecular biology.
  • Experience working with a variety of information systems and data files, including analyzing file structure, and using and creating layouts of large and complex files.
  • Demonstrated ability to manage, manipulate, and interpret large biological data sets, transforming raw data into finished products.
  • Working knowledge of data analysis and statistical methods used in genomics and bioinformatics.
  • Excellent cross-platform computing skills, including experience using Linux/Unix Operating Systems, Macintosh OS X and Windows operating systems.
  • Experience in Perl and Java programming as well as statistical languages such as R, SAS, or Matlab.
  • Proficiency with Microsoft Excel or other spread sheet applications.
  • Proven critical thinking skills and the ability to consider outcomes when designing analyses.
  • The ability to be self-motivated and work independently, with minimal supervision, while also working as part of a team environment in a dynamic organization.
  • Strong interpersonal and communication skills, both written and spoken, with a confident and cooperative service-oriented attitude.
  • Ability to read, write, speak and understand English required.

HIGHLY QUALIFIED CANDIDATES WILL POSSESS

  • Basic knowledge of relational database structure and terminology.
  • Laboratory research experience in genetics, molecular biology, immunology or biochemistry.
  • Demonstrated experience in DNA or RNA sequence analysis and presentation of results.

Salary is commensurate with experience and qualifications. Excellent benefits package including employer paid medical, dental, vision, vacations and holidays. Adaptive Biotechnologies is proud to be an Equal Opportunity Employer and offer a smoke & drug free environment.

If you are a bright, career-minded individual we want to hear from you! Please submit your resume and cover letter to careers@adaptivebiotech.com.

Clinical Molecular Laboratory Director
OVERVIEW
Adaptive Biotechnologies Corp. seeks highly qualified applicants for a Clinical Molecular Laboratory Director. Adaptive is an early stage biotechnology company commercializing a patented technology to measure vital properties of the human immune system.

Adaptive’s proprietary method for sequencing genes relating to the adaptive immune system has direct application on the diagnosis and monitoring of leukemia, lymphoma, and solid tumors. Clinical patient testing is done as part of our ClonoSEQ platform and is performed at our CLIA-certified laboratory in Seattle, WA. The Clinical Molecular Lab Director would be responsible for the overall leadership, operation and administration of the clinical laboratory and for ensuring that all studies are conducted with the highest level of ethical and safety standards and are in compliance with GCP and all regulatory policies.

RESPONSIBILITIES

  • Plan, develop, organize, implement, direct and evaluate the organization’s laboratory operations and performance.
  • Define, implement, and monitor standards of performance in quality control, quality improvement, and cost-effectiveness of the clinical laboratory services.
  • Provide on-site monitoring of all work performed in the laboratory to determine that medically reliable data are being generated; correlate laboratory data for diagnosis, prognosis and patient management.
  • Ensure that testing systems developed and used for each of the tests performed in the laboratory provide quality laboratory services for all aspects of test performance.
  • Ensure that the test methodologies selected have the capability of providing the quality of results required for patient care.
  • Provide consultations about medical significance of clinical laboratory data. Interpret, correlate, and communicate laboratory data to clinical requestors.
  • Leads or supports the preparation of clinical protocols, integrated clinical and statistical summary reports, clinical sections included in various regulatory submissions.
  • Relate and function effectively with applicable accrediting and regulatory agencies, appropriate administrative officials, the medical community, the medical device industry, and the patient population served.
  • Lead and oversee the laboratory staff.
  • Ensure that there are sufficient qualified personnel with adequate documented training and experience to meet the needs of the laboratory.
  • Contribute as part of a cross-functional team to the clinical development strategy, including the clinical development plans and operational plans for various malignancies
  • Provide effective and efficient administration of the clinical laboratory service including budget planning and control with responsible financial management.
  • Provide educational programs for the laboratory staff, and participate in educational programs of the institution.
  • Select and monitor all laboratories for quality service
  • Implement a safe laboratory environment in compliance with good practice and applicable regulations.
  • Supports various meetings with external experts, advisors and business development teams.

REQUIRED SKILLS, ABILITIES, & CREDENTIALS

  • Ph.D., M.D. or M.D./Ph.D. with ABMG certification in Clinical Molecular Genetics or M.D., M.D./Ph.D. with ABP certification in Molecular Genetic Pathology or Oncology is required.
  • A minimum of 3+ years of experience in the management of clinical laboratory operations, molecular genetic assay validation, and reporting, including supervision of staff in a CLIA compliant environment.
  • Strong track record of leadership and collaboration in deploying clinical genomics applications with latest next-generation sequencing and informatics methodologies.
  • Reside on-site at Adaptive and take an active role in management and strategic visions with proactive thinking.

Salary is commensurate with experience and qualifications. Excellent benefits package including employer paid medical, dental, vision, vacations and holidays. Adaptive Biotechnologies Corp. is proud to be an Equal Opportunity Employer, and offer a smoke and drug free environment.

If you are a bright, career-minded individual we want to hear from you! Please submit your resume and cover letter to careers@adaptivebiotech.com.

Grants Specialist
OVERVIEW
Adaptive Biotechnologies Corp. seeks a full time Grants Specialist to secure solicitations, prepare and submit applications, and complete all award and administrative reporting functions for current and future Adaptive research initiatives. The grants specialist’s focus is on pre-award opportunity recruitment, organization and application preparation, post-award project management and closeout.

RESPONSIBILITIES

Responsible for both Pre-Award and Post-Award grants and contract management including award acceptance, award activation and tracking grants and the status of required progress and compliance reports. Award types focused on Small Business Innovation Research Grants (SBIRs) from NIH, NSF, DoD, and may include NIH research grants. This position will support all types of federal and NGO grant submissions and management.

This individual will be responsible for the review and administration of agreements related to sponsored projects, including proposal review, grant and contract negotiations and post award administration. Will terminate and close out awards, monitor preparation of reports on property, patents, expenditures and the like; obtain instructions and disposition of overruns, etc. Advise and consult with appropriate personnel on preparation of proposals, budgets, cost sharing, and effort monitoring.

Pre-Award activities include:

  • Direct and proactively work with Adaptive grant team in all aspects of grant and contract proposal preparation, including finding and notifying grant team of funding opportunities, preparing and tracking proposal status through the various submission agencies (e.g. Grants.gov and assisting in preparing IRB submissions.
  • Review and interpret guidelines for specific proposal submission as outlined in sponsor Requests for Applications/Proposals and Program Announcements.
  • Maintain training in the use of online submission systems such as GRANTS.GOV, FASTLANE, etc., and enter data into the online system for submission.
  • Advise on funding agency proposal requirements, drafting budgets and justifications, and management of documentation and form preparation, approval monitoring, and forwarding to funding agencies to meet frequent deadlines.
  • Determine appropriate needs to project and prepare requests with
  • multiple contracts and sub-contracts.
  • Understand, plan, prepare and ensure appropriate documentation for accounting on grant proposals. Monitor and ensure compliance with State and Federal audit requirements.
  • Maintain thorough knowledge of NIH, NSF submission policies, procedures, standards and deadlines; maintain knowledge of applicable OMB circulars.
  • Setup and attend conference calls for PI and NIH/NSF PO staff as needed
  • Communicate with grants management specialists (GMS) regarding submissions, budgeting, NOA as needed.
  • Negotiate award terms. Highlight anticipated compliance issues during pre-award stage.

Post-Award Responsibilities include:

  • Manage post-award grants process. Coordinate the setting up of new
  • projects; provide appropriate spending allocation information; troubleshoot and resolve problems; provide analysis, guidance and oversight on all post-award grants and contracts management issues.
  • Review Notice of Award (NOA) to ensure appropriate budget and project periods
  • Prepare related paperwork for sub-contracts and or sub-budgets, etc.
  • Monitor budgets to ensure appropriate support in resource management and staffing levels (e.g. FTEs do not exceed 100%).
  • Maintain budget tracking, reporting and record keeping systems to monitor fiscal activity of research budgets from award to closeout.
  • Prepare on-line budget transaction transfers, no cost extensions, request for re-budgeting, and all other budget actions as needed.
  • Regularly communicate with NIH or NSF staff as needed to ensure appropriate reporting (e.g. progress reports, FFR, quarterly and final reports).
  • Prepare budget close out and final reporting to sponsor (in conjunction with PI).
  • Regularly attend grant team meetings to update team on any proposal or budget issues in timely fashion.

Other:

  • May be asked to fulfill other duties and responsibilities as required.
  • Perform such other duties as may be assigned including serving on committees, and working on special projects.
  • Will attend local/regional meetings of professional research administrators and keep abreast of changes in sponsor requirements and legislation affecting sponsored programs.

REQUIRED SKILLS AND ABILITIES AND CREDENTIALS

The individual in this position must have strong operational and administrative experience and expertise, excellent interpersonal and relationship skills, and absolute discretion. Strong organization skills; strong oral and written communication skills; ability to handle multiple tasks; ability to work under deadlines and prioritize workload; ability to reprioritize quickly as new information about clients’ needs become clear; ability to work in a supportive and collaborative fashion within the Adaptive team and with a diverse range of clients and colleagues; ability to communicate technical details clearly and respectfully to colleagues who may be unfamiliar with the process described. Bachelor’s degree required and 3-5 years of experience working in support of grant administration is strongly preferred.

Experience with NIH grant and contract submission required, SBIR submissions, NSF, and DoD preferred. Project management or coordination experience highly desired.

Salary is commensurate with experience and qualifications. Excellent benefits package including employer paid medical, dental, vision, vacations and holidays. Adaptive Biotechnologies Corp. is proud to be an Equal Opportunity Employer, and offer a smoke and drug free environment.

If you are a bright, career-minded individual we want to hear from you! Please submit your resume and cover letter to careers@adaptivebiotech.com.

Purchasing Agent
OVERVIEW
Adaptive is currently seeking a part-time Purchasing Agent to join our growing team in Seattle, WA. This position will be responsible for procurement of supplies needed for laboratory and office operations. The ideal candidate will have experience working directly with vendors to negotiate pricing, setting up standing orders, tracking and validation of incoming orders, and maintaining records for financial accounting.

RESPONSIBILITIES

  • Work with team members to identify appropriate vendors
  • Submit and track purchase orders
  • Maintain detailed and accurate records for orders (e.g. validate packing slips)
  • Track and maintain inventory for all critical lab reagents and office supplies
  • Negotiate pricing with major vendors
  • Structure the current order and expense management software for maximum efficiency
  • Other related responsibilities as needed

REQUIREMENTS

  • Bachelor’s degree
  • 2+ years of experience as a purchasing agent or related administrative experience
  • Experience with inventory control and management
  • Detailed oriented and organized with service driven attitude
  • Experience with purchasing management or financial accounting software is a plus

Salary is commensurate with experience and qualifications. Excellent benefits package including employer paid medical, dental, vision, vacations and holidays. Adaptive Biotechnologies Corp. is proud to be an Equal Opportunity Employer, and offer a smoke and drug free environment.

If you are a bright, career-minded individual we want to hear from you! Please submit your resume and cover letter to careers@adaptivebiotech.com.