Beatriz Carreno, PhD - University of Pennsylvania
Scientific Question: Can we use genomic information to create better vaccines against cancer?
Karen Cerosaletti, PhD - Benaroya Research Institute
Scientific Question: Can we identify T-cell receptor signatures that track autoimmune disease type 1 diabetes?
Richard Dipaolo, PhD - Saint Louis University, School of Medicine
Scientific Question: Can we identify antigen specific TCRs and track the relative TCR frequencies during an immune response to infections or vaccines?
Kathryn Hulse, PhD - Northwestern University
Scientific Question: What is the mechanism of B-cell activation in inflammation associated with chronic rhinosinusitis (CRS)?
Joseph Leventhal, MD, PhD - Northwestern University Feinberg School of Medicine
Scientific Question: Can recipients of kidney plus HSC/FC transplant establish graft tolerance while recovering immunocompetence?
Vinay Mahajan, PhD - Mass General Hospital
Scientific Question: What can we learn about the pathogenesis of IgG4-related disease, a poorly understood immune-mediated disorder of possible autoimmune etiology?
Carolina Moore, PhD - Harvard Medical School
Scientific Question: Can we identify and characterize the B-cell population that infiltrates cardiac tissue after transplant?
Robert Prins, PhD - David Geffen School of Medicine at UCLA
Scientific Question: Can immunosequencing help predict clinical responses after dendritic cell vaccination in patients with glioblastoma?
Ran Reshef, PhD - University of Pennsylvania
Scientific Question: What is the role of T-cell trafficking in the development of graft versus host disease (GVHD) after hematopoietic stem-cell transplantation (HSCT)?
Cassian Yee, MD - University of Texas MD Anderson Cancer Center; Fred Hutchinson Cancer Research Center
Scientific Question: How do tumor-specific T-cell populations change after personalized therapy to melanoma?
Meet Our Young Investigators - Award Recipients
Each quarter, we select one or more applicants for our Young Investigator Award to assist with their immunology-focused research. Each award winner receives a $5,000 grant to use for sequencing.
Understanding the Immunopathogenesis of Multiple Sclerosis - 7:00 minutes
Stefan Gold, PhD, discusses how his team used immunoSEQ® Technology in research investigating how pregnancy modulates the immune system, an area in which standard technologies have not proven effective.
Researching Immune Tolerance in Transplantation - 6:59 minutes
Megan Sykes, MD, talks about the how the immunoSEQ® Assay allowed her to investigate mechanism of tolerance for a unique combined bone marrow and kidney transplant protocol which increases the tolerance and likelihood of successful transplantations.
Researching Immuno-Oncology - 4:11 minutes
Padmanee Sharma, MD, PhD shares how the immunoSEQ® Assay helped her team build their immunotherapy program at MD Anderson by enabling them to monitor immunotherapy trial patients by analyzing and tracking T-cell clones.
AAI 2015 immunoSEQ Workshop - 45:13 minutes
Three presentations from a corporate workshop at the 2015 America Association of Immunologists (AAI) meeting. Catherine Sanders, PhD, gives an introduction to the technology behind the immunoSEQ® Platform and Megan Sykes, MD, and Federica Sallusto, PhD, share how they have applied this technology to make discoveries in their research.