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Both Service and Kit sequencing data is delivered through a secure cloud-based platform with cutting-edge analytic tools designed specifically for immunosequencing data.
wide range of loci
Using our proprietary highly optimized multiplex PCR primers, rearranged T-cell and B-cell receptor genes are exclusively targeted and sequenced using Illumina® technology for the following loci:
flexible sample requirements
Appropriate sample types include genomic (gDNA) and complementary DNA (cDNA)* from the following lymphocyte-containing tissues:
* cDNA is accepted for all Service assays other than mouse IGH, and is not supported for Kit assays
**FFPE is not supported for Kit assays
immunoSEQ Assays give researchers a high-definition view of the adaptive immune system. It’s now possible to explore broad characteristics of T-and B-cell repertoires as well as the unique details of individual clones. Whether you are investigating the general trends of the immune system or specific clones, you can be confident in your data with the quantitative and reproducible results of immunoSEQ Assays behind your research.
Employing highly optimized PCR primers and a synthetic immune repertoire with computational algorithms, the immunoSEQ Assay delivers accurate, quantifiable results.
U.S. Patent Nos. 9,150,905 and 9,371,558
Primer concentrations adjusted to significantly reduce PCR amplification bias
Built-in controls assessed with every sample for true quantification
Corrects residual PCR amplification bias and quantifies T-cell or B-cell clones