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A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL-2-Receptor Beta/Gamma (βγ)-Biased Cytokine, in Patients With Advanced or Metastatic Solid Tumors

Bentebibel et al.
Cancer Discovery
April 2019
Authors and Affiliates
Salah-Eddine Bentebibel1*, Michael E. Hurwitz2*, Chantale Bernatchez1*, Cara Haymaker1, Courtney W. Hudgens1, Harriet M. Kluger2, Michael T. Tetzlaff1, Mary A. Tagliaferri3, Jonathan Zalevsky3, Ute Hoch3, Christie Fanton3, Sandra Aung3, Patrick Hwu1, Brendan D. Curti4, Nizar M. Tannir1, Mario Sznol2, Adi Diab1; 1. The University of Texas MD Anderson Cancer Center, Houston, TX 2. Yale School of Medicine, New Haven, CT 3. Nektar Therapeutics, San Francisco, CA 4. Providence Cancer Institute and Earle A. Chiles Research Institute, Portland, OR *These authors contributed equally