The impact of CTLA-4 blockade and interferon-α on clonality of T-cell repertoire in the tumor microenvironment and peripheral blood of metastatic melanoma patients

Khunger A1, Rytlewski JA2, Fields P2, Yusko EC2, Tarhini AA3; 1 Department of Hematology and Oncology, Cleveland Clinic, Cleveland, OH, USA. 2 Adaptive Biotechnologies, Seattle, WA, USA. 3 Department of Cutaneous Oncology, Moffitt Comprehensive Cancer Center, Tampa, Florida, USA.