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Common clonal origin of central and resident memory T cells following skin immunization
Authors and Affiliates
Gaide O1, Emerson RO2, Jiang X1, Gulati N3, Nizza S1, Desmarais C2, Robins H4, Krueger JG3, Clark RA1, Kupper TS1
1Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
2Adaptive Biotech, Seattle, Washington, USA.
3Laboratory for Investigative Dermatology, Rockefeller University, New York, New York, USA.
4Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Human and Murine Clonal CD8+ T Cell Expansions Arise During Tuberculosis Because of TCR Selection
Nunes-Alves et al.
Papers
PLOS Pathogens
May 2015
Authors and Affiliates
Nunes-Alves C1, Booty MG2, Carpenter SM3, Rothchild AC2, Martin CJ4, Desjardins D5, Steblenko K6, Kløverpris HN7, Madansein R8, Ramsuran D9, Leslie A10, Correia-Neves M11, Behar SM6.
Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3
Goettel et al.
Blood Journal
Papers
April 2015
Authors and Affiliates
Goettel JA1,2, Biswas S2,3, Lexmond WS1,2, Yeste A2,4, Passerini L5, Patel B2,4, Yang S6, Sun J2,3, Ouahed1,2, Shouval DS1,2, McCann KJ1, Horwitz BH2,7, Mathis D6, Milford EL2,8, Notarangelo LD2,9, Roncarolo MG5,10, Fiebiger E1,2, Marasco WA2,3, Bacchetta R5, Quintana FJ2,4, Pai SY2,11,12, Muise AM13, Snapper SB1,2,14
Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston MA1; Department of Medicine, Harvard Medical School, Boston MA2; Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston MA3; Center for Neurologic Diseases, Brigham and Women's Hospital, Boston MA4; Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy, Milan, Italy5; Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA6; Department of Pathology, Brigham and Women's Hospital, Boston, MA7; Renal Division of Tissue Typing Laboratory, Brigham and Women's Hospital, Boston, MA8; Division of Immunology and the Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA9; Vita-Salute San Raffaele University, Milan, Italy10; Division of Hematology-Oncology, Boston Children's Hospital, Boston, MA11; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA12; Division of Gastroenterology, Hepatology, and Nutrition, Department of Paediatrics, Hospital for Sick Children, Toronto, CA13; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA14
A dendritic cell vaccine increases the breadth of diversity of melanoma neoantigen-specific T cells
Carreno et al.
Papers
ScienceXpress
April 2015
Authors and Affiliates
Carreno BM1, Magrini V2, Becker-Hapak M1, Kaabinejadian S3, Hundal J2, Petti AA2, Ly A2, Lie WR4, Hildebrand WH3, Mardis ER2, Linette GP1
Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO1; Genome Institute, Washington University School of Medicine, St. Louis MO2; Department of Microbiology and Immunology, University of Oklahoma Health Science Center, Oklahoma City, OK3; EMD Millipore Corporation, Billerica, MA4
CMV reactivation drives post-transplant T cell reconstitution and results in defects in the underlying TCRβ repertoire
Authors and Affiliates
Suessmuth Y1, Mukherjee R2, Watkins B3, Koura DT4, Finstermeier K5, Desmarais C5, Stempora L1, Horan JT3, Langston A4, Qayed M3, Khoury HJ4, Grizzle A3, Chessman JA1, Conger JA1, Robertson J1, Garrett A3, Kirk AD1, Waller EK4, Blazar BR6, Mehta AK1, Robins HS2, Kean LS7
1The Emory Transplant Center, Emory University School of medicine, Atlanta, GA; 2Fred Hutchinson Cancer Research Center, Seattle, WA; 3Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA; 4Winship Cancer Institute of Emory University, Atlanta, GA; 5Adaptive Biotechnologies Corp, Seattle, WA; 6Department of Pediatrics, Division of Blood and Morrow Transplantation, University of Minnesota School of Medicine, Minneapolis, MN; 7Ben Towne Center for Childhood Cancer Research, Seattle, WA
Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis
Salou et al
Annals of Clinical and Translational Neurology
Papers
April 2015
Authors and Affiliates
Salou M1, Garcia A2, Michel L3, Gainche-Salmon A4, Loussouarn D5, Nicol B1, Guillot F1, Hulin P6, Nedellec S6, Baron D7, Ramstein G8, Soulillou JP4, Brouard S2, Nicot AB7, Degauque N2, Laplaud DA9.
Changes in peanut-specific T-cell clonotype with oral immunotherapy
Bégin et al.
Papers
The Journal of Allergy and Clinical Immunology
April 2015
Authors and Affiliates
Bégin, P1, Nadeau, KC2.
1Department of Pediatrics, Sainte-Justine Hospital, Montreal, Quebec, Canada; Department of Medicine, University of Montreal Health Center, Montreal, Quebec, Canada.
2Division of Allergy, Immunology and Rheumatology, Sean N. Parker Center for Allergy Research at Stanford University, Stanford University School of Medicine, Stanford, Calif
Peripheral Blood-Derived Virus-Specific Memory Stem T cells Mature to Functional Effector Memory subsets with Self-Renewal Potency
Schmueck-Henneresse et al
Journal of Immunology
Papers
April 2015
Authors and Affiliates
Schmueck-Henneresse M1, Sharaf R2, Vogt K2, Weist BJ3, Landwehr-Kenzel S4, Fuehrer H5, Jurisch A6, Babel N7, Rooney CM8, Reinke P5, Volk HD6.
CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo
Hanley, et al.
Papers
Science Translational Medicine Editorial
April 2015
Authors and Affiliates
Patrick J. Hanley,1,2,3 Jan J. Melenhorst,4 Sarah Nikiforow,5 Phillip Scheinberg,4 James W. Blaney,1 Gail Demmler-Harrison,6 C. Russell Cruz,1,3 Sharon Lam,1,2,3 Robert A. Krance,1,6,7 Kathryn S. Leung,1,6 Caridad A. Martinez,1,6 Hao Liu,1 Daniel C. Douek,8 Helen E. Heslop,1,6,7 Cliona M. Rooney,1,2,6,7,9 Elizabeth J. Shpall,10 A. John Barrett,4 John R. Rodgers,2 Catherine M. Bollard1,2,3,6,7*
1Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children’s Hospital, and Houston Methodist Hospital, Houston, TX 77030, USA. 2 Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA. 3 Program for Cell Enhancement and Technologies for Immunotherapy, The Sheikh Zayed Institute for Pediatric Surgical Innovation, the Center for Cancer and Immunology Research, and the Division of Blood and Marrow Transplantation, Children’s National Health System and The George Washington University, Washington, DC 20052, USA. 4 Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA. 5 Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney St., Boston, MA 02115, USA. 6 Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA. 7 Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. 8 Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. 9 Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA. 10Department of Stem Cell Transplantation and Cellular Therapy, MD Anderson Cancer Center, Houston, TX 77030, USA.