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Using synthetic templates to design an unbiased multiplex PCR assay

Carlson et al.
Nature Communications
Papers
April 2013
Authors and Affiliates
Carlson CS1, Emerson RO2, Sherwood AM2, Desmarais C2, Chung MW2, Parsons JM2, Steen MS2, LaMadrid-Herrmannsfeldt MA2, Williamson DW2, Livingston RJ2, Wu D3, Wood BL3, Rieder MJ2, Robins H1, 2. 1Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, Washington 98109, USA 2Adaptive Biotechnologies, Seattle, Washington, USA. 3Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA.

Fractal Organization of the Human T Cell Repertoire in Health and After Stem Cell Transplantation

Meier et al.
Biology of Blood Marrow Transplant
Papers
March 2013
Authors and Affiliates
Jeremy Meier1, Catherine Roberts1, Kassi Avent2, Allison Hazlett1, Jennifer Berrie2, Kyle Payne2, David Hamm3, Cindy Desmarais3, Catherine Sanders3, Kevin T. Hogan4, Kellie J. Archer5, Masoud H. Manjili2, Amir A. Toor1. 1Bone Marrow Transplant Program, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA. 2Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia. 3Adaptive Biotechnologies, Seattle, Washington. 4Massey Cancer Center, Richmond, Virginia. 5Department of Biostatistics, Virginia Commonwealth University, Richmond, Virginia

CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

Brentjens et al.
Papers
Science Translational Medicine
March 2013
Authors and Affiliates
Brentjens RJ1, Davila ML, Riviere I, Park J, Wang X, Cowell LG, Bartido S, Stefanski J, Taylor C, Olszewska M, Borquez-Ojeda O, Qu J, Wasielewska T, He Q, Bernal Y, Rijo IV, Hedvat C, Kobos R, Curran K, Steinherz P, Jurcic J, Rosenblat T, Maslak P, Frattini M, Sadelain M. 1Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY.

Immune Recovery in Adult Patients Following Myeloablative Dual Umbilical Cord Blood, Matched Sibling, and Matched Unrelated Donor Hematopoietic Cell Transplantation

Kanda et al.
Biology of Blood and Marrow Transplantation
Papers
December 2012
Authors and Affiliates
Junya Kanda, MD,1,6,* Lun-Wei Chiou, MD,1,* Paul Szabolcs, MD,2 Gregory D. Sempowski, PhD,3 David A. Rizzieri, MD,1 Gwynn D. Long, MD,1 Keith M. Sullivan, MD,1 Cristina Gasparetto, MD,1 John P. Chute, MD,1 Ashley Morris, PharmD,1 Jacalyn McPherson,1 Jeffrey Hale,3 John Andrew Livingston, MD,1 Gloria Broadwater, MS,4 Donna Niedzwiecki, PhD,5 Nelson J. Chao, MD,1 and Mitchell E. Horwitz, MD1,** 1Division of Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC 2Department of Pediatrics, Duke University Medical Center, Durham, NC 3Department of Medicine and Human Vaccine Institute, Duke University School of Medicine, Durham, NC 4Cancer Statistical Center, Duke University Medical Center, Durham, NC 5Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 6Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan. **Corresponding author: Mitchell E. Horwitz, MD, Division of Cellular Therapy, Department of Medicine, Duke University Medical Center, 2400 Pratt Street, DUMC 3961, Durham, NC 27705, USA. *J.K. and L.C. equally contributed to this work.

Shaping of human germline IgH repertoires revealed by deep sequencing

Larimore et al.
Journal of Immunology
Papers
September 2012
Authors and Affiliates
Kevin Larimore,* Michael W. McCormick,† Harlan S. Robins,‡ and Philip D. Greenberg*,x,{ *Department of Immunology, University of Washington, Seattle, WA 98195 † Adaptive Biotechnologies Corp., Seattle, WA 98109 ‡ Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 x Department of Medicine, University of Washington, Seattle, WA 98195 { Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109

Statistical Inference of the Generation Probability of T-cell Receptors from Sequence Repertoires

Murugana et al.
Papers
Proceedings of the National Academy of Sciences
July 2012
Authors and Affiliates
Anand Murugan1, Thierry Mora2, Aleksandra M. Walczak3, Curtis G. Callan, Jr.1,4 1 Joseph Henry Laboratories, Princeton University, Princeton, NJ. 2 Laboratoire de Physique Statistique, UMR8550, Centre National de la Recherche Scientifique and École Normale Supérieure, Paris, France. 3 Laboratoire de Physique Théorique, UMR8549, Centre National de la Recherche Scientifique and École Normale Supérieure, Paris, France. 4 Simons Center for Systems Biology, Institute for Advanced Study, Princeton, NJ.