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Large-scale statistical mapping of T-cell receptor β sequences to Human Leukocyte Antigens
H. Jabran Zahid, et al.
bioRxiv
Pre-Print
April 2024
Authors and Affiliates
H. Jabran Zahid 1, Ruth Taniguchi 2, Peter Ebert 2, I-Ting Chow 2, Chris Gooley 1, Jinpeng Lv 1, Lorenzo Pisani 1, Mikaela Rusnak 2,Rebecca Elyanow 2, Hiroyuki Takamatsu 3, Wenyu Zhou 2, Julia Greissl 1, Harlan Robins 2 and Jonathan M. Carlson 1;
1 Microsoft Research - 14820 NE 36th St, Redmond, WA 98052; 2 Adaptive Biotechnologies - 1165 Eastlake Ave E, Seattle, WA 98109; 3 Faculty of Transdisciplinary Sciences for Innovation, Institute of Transdisciplinary Sciences for Innovation/ Department of Hematology, Kanazawa University, Kakumamachi, Kanazawa, Ishikawa 920-1192, Japan.
Identifying immune signatures of common exposures through co-occurrence of T-cell receptors in tens of thousands of donors
May DH, et al.
bioRxiv
Pre-Print
March 2024
Authors and Affiliates
Damon H. May 1, Steven Woodhouse 1, H. Jabran Zahid 2, Rebecca Elyanow 1, Kathryn Doroschak 1, Matthew T. Noakes 1, Ruth Taniguchi 1, Zheng Yang 1, John R. Grino 1, Rachel Byron 1, Jamie Oaks 1, Anna Sherwood 1, Julia Greissl 2, Haiyin Chen-Harris 1, Bryan Howie 1, Harlan S. Robins 1
1: Adaptive Biotechnologies - 1165 Eastlake Ave E, Seattle, WA 98109
2: Microsoft Research - 14820 NE 36th St, Redmond, WA 98052
CD22 CAR T cells demonstrate high response rates and safety in pediatric and adult B-ALL: Phase 1b results
Schultz L, et al.
Leukemia
March 2024
Authors and Affiliates
Liora M. Schultz1,2,6, Nikeshan Jeyakumar3,6, Anne Marijn Kramer 2, Bita Sahaf2, Hrishi Srinagesh3, Parveen Shiraz4, Neha Agarwal4,
Mark Hamilton3, Courtney Erickson1, Ashley Jacobs1, Jennifer Moon1, Christina Baggott1, Sally Arai4, Sushma Bharadwaj4,
Laura J. Johnston4, Michaela Liedtke3, Robert Lowsky4, Everett Meyer4, Robert Negrin4, Andrew Rezvani4, Judy Shizuru 4,
Surbhi Sidana 4, Emily Egeler2, Sharon Mavroukakis2, Ramya Tunuguntla5, Nikolaos Gkitsas-Long5, Aidan Retherford5,
Annie Kathleen Brown5, Anne-Louise Gramstrap-Petersen5, Raquel Martin Ibañez5, Steven A. Feldman2,5, David B. Miklos 2,4,
Crystal L. Mackall 1,2, Kara L. Davis1,2, Matthew Frank2,4, Sneha Ramakrishna1,2 and Lori Muffly 2,4
1Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA. 2Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA. 3Division of
Hematology, Stanford University, Stanford, CA, USA. 4Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA. 5Laboratory for
Cell and Gene Medicine, Stanford University, Stanford, CA, USA. 6These authors contributed equally: Liora M. Schultz, Nikeshan Jeyakumar. ✉email: lmuffly@stanford.edu
Expanded specific T cells to hypomutated regions of the SARS-CoV-2 using mRNA electroporated antigen-presenting cells
Ogando-Rivas E, et al.
Molecular Therapy
February 2024
Authors and Affiliates
Elizabeth Ogando-Rivas, Paul Castillo, Changlin Yang, Vrunda Trivedi, Dingpeng Zhang, Fernanda Pohl-Guimarães, Ruixuan Liu, Arnav Barpujari, Kate M. Candelario, Hector Mendez-Gomez, Elias J. Sayour and Duane A. Mitchell.
Complete loss of TP53 and RB1 is associated with complex genome and low immune infiltrate in pleomorphic rhabdomyosarcoma
Beird H et al.
HGG Advances
February 2024
Authors and Affiliates
Hannah C. Beird; Chia-Chin Wu; Michael Nakazawa; Davis Ingram; Joseph R. Daniele; Rossana Lazcano; Latasha Little; Christopher Davies; Najat C. Daw; Khalida Wani; Wei-Lien Wang; Xingzhi Song; Curtis Gumbs; Jianhua Zhang; Brian Rubin; Anthony Conley; Adrienne M. Flanagan; Alexander J. Lazar and P. Andrew Futreal.
Antigen-presenting B cells promote TCF-1+ PD1-stem-like CD8+ T-cell proliferation in glioblastoma
Hou D et al.
Frontiers in Immunology
February 2024
Authors and Affiliates
David Hou; Hanxiao Wan; Joshua L. Katz; Si Wang; Brandyn A. Castro; Gustavo I. Vazquez-Cervantes; Victor A. Arrieta; Silpol Dhiantravan; Hinda Najem; Aida Rashidi; Tzu-yi Chia; Tarlan Arjmandi; Jimena Collado; Leah Billingham; Aurora Lopez-Rosas; Yu Han; Adam M. Sonabend; Amy B. Heimberger; Peng Zhang; Jason Miska and Catalina Lee-Chang.
Immune profiling of patients with extranodal natural killer/T cell lymphoma treated with daratumumab
Qing M et al.
Annals of Hematology
February 2024
Authors and Affiliates
Min Qing; Tianyuan Zhou; Tatiana Perova; Yann Abraham; Cheryl Sweeney; Maria Krevvata; Xiaokang Zhang; Ming Qi; Grace Gao; Tae Min Kim; Ming Yao; Seok‑Goo Cho; Hyeon Seok Eom; Soon Thye Lim; Su‑peng Yeh; Yok Lam Kwong; Dok Hyun Yoon; Jin Seok Kim; Won Seog Kim; Longen Zhou; Ricardo Attar; Raluca I. Verona.
Single-cell analysis of immune recognition in chronic myeloid leukemia patients following tyrosine kinase inhibitor discontinuation
Huuhtanen, J et al.
Nature
February 2024
Authors and Affiliates
Jani Huuhtanen; Shady Adnan-Awad; Jason Theodoropoulos; Sofia Forstén; Rebecca Warfvinge; Olli Dufva; Jonas Bouhlal; Parashar Dhapola; Hanna Duàn; Essi Laajala; Tiina Kasanen; Jay Klievink; Mette Ilander; Taina Jaatinen; Ulla Olsson-Strömberg; Henrik Hjorth-Hansen; Andreas Burchert; Göran Karlsson; Anna Kreutzman; Harri Lähdesmäki and Satu Mustjoki.
Single agent subcutaneous blinatumomab for advanced acute lymphoblastic leukemia
Jabbour E, et al.
American Journal of Hematology
February 2024
Authors and Affiliates
Elias Jabbour1 | Gerhard Zugmaier2 | Vaibhav Agrawal3 |
Pilar Martínez-Sánchez4 | José J. Rifon Roca5 | Ryan D. Cassaday6,7 |
Boris Böll8 | Anita Rijneveld9 | Maher Abdul-Hay10 | Françoise Huguet11 |
Thomas Cluzeau12 | Mar Tormo Díaz13 | Vladan Vucinic14 |
José González-Campos15 | Alessandro Rambaldi16 | Stefan Schwartz17 |
Céline Berthon18 | Jesús María Hernández-Rivas19,20,21 | Paul R. Gordon22 |
Monika Brüggemann23 | Ali Hamidi22 | Yuqi Chen22 | Hansen L. Wong24 |
Bharat Panwar22 | Yuliya Katlinskaya22 | Ana Markovic22 | Hagop Kantarjian1
1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
2Amgen Research (Munich), GmbH, Munich, Germany
3Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte,
California, USA
4Department of Hematology, Hospital Universitario 12 de Octubre, Instituto de Investigacion Sanitaria Hospital 12 de Octubre (imas12), CNIO, CIBERONC, Madrid, Spain
5Hematology and Hemotherapy Department, Clínica Universidad de Navarra, Pamplona, Spain
6Division of Hematology and Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
7Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA
8First Department of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, University of Cologne, Cologne, Germany
9Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands
10Perlmutter Cancer Center, New York University Langone Health, New York, New York, USA
11Department of Hematology, Institut Universitaire du Cancer-Oncopole CHU de Toulouse, Toulouse, France
12Université Nice Côte d'Azur, CHU de Nice, Nice, France
13Hematology Department, Hospital Clínico Universitario de Valencia, Instituto de Investigacion Sanitaria INCLIVA, Valencia, Spain
14Department of Hematology and Cell Therapy, University Hospital Leipzig, Leipzig, Germany
15Hematology Department, Hospital Universitario Virgen del Rocío, Sevilla, Spain
16Department of Oncology-Hematology, University of Milan, Milan and Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy
17Department of Hematology, Oncology and Tumor Immunology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität and Humboldt-
Universität zu Berlin, Campus Benjamin Franklin, Berlin, Germany
18Centre Hospitalier Universitaire de Lille, Lille, France
19IBSAL, IBMCC, CSIC, Cancer Research Center, University of Salamanca, Salamanca, Spain
20Department of Hematology, University Hospital of Salamanca, Salamanca, Spain
21CIBERONC, Research Group CB16/12/00233, Salamanca, Spain
22Amgen Inc., Thousand Oaks, California, USA
23Department of Hematology, University of Schleswig-Holstein, Kiel, Germany
24Clinical Pharmacology, Modeling and Simulation, Amgen Inc., South San Francisco, California, USA