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Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro

Schmitt et al.
Nature Biotechnology
Papers
November 2017
Authors and Affiliates
Thomas M Schmitt1, David H Aggen2, Kumiko Ishida-Tsubota1, Sebastian Ochsenreither3, David M Kranz2 & Philip D Greenberg1,4 1Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. 2Department of Biochemistry, University of Illinois at Urbana–Champaign, Urbana, Illinois, USA. 3Department of Hematology, Oncology, and Tumor Immunology, Charité Campus Benjamin Franklin, Berlin, Germany. 4Departments of Immunology and Medicine, University of Washington, Seattle, Washington, USA