Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes

Alena Gros,1 Eric Tran,2,3 Maria R. Parkhurst,2 Sadia Ilyas,2 Anna Pasetto,4 Eric M. Groh,2 Paul F. Robbins,2 Rami Yossef,2 Andrea Garcia-Garijo,1 Carlos A. Fajardo,1 Todd D. Prickett,2 Li Jia,2 Jared J. Gartner,2 Satyajit Ray,2 Lien Ngo,2 John R. Wunderllich,2 James C. Yang,2 and Steven A. Rosenberg2 1Vall d’Hebron Institute of Oncology, Cellex Center, Barcelona, Spain. 2Surgery Branch, National Cancer Institute, NIH, Bethesda, Maryland, USA. 3Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Cancer Institute, Portland, Oregon, USA. 4Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.