Therapeutic Area: Autoimmune
Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID
Grady et al.
Communications Medicine
January 2026
Authors and Affiliates
Connor B. Grady, Bornali Bhattacharjee, Julio Silva, Jillian Jaycox, Lik Wee Lee, Valter Silva Monteiro, Mitsuaki Sawano, Daisy Massey, César Caraballo, Jeff R. Gehlhausen, Alexandra Tabachnikova, Tianyang Mao, Carolina Lucas, Mario A. Peña-Hernandez, Lan Xu, Tiffany J. Tzeng, Takehiro Takahashi, Jeph Herrin, Diana Berrent Güthe, Athena Akrami, Gina Assaf, Hannah Davis, Karen Harris, Lisa McCorkell, Wade L. Schulz, Daniel Griffin, Hannah Wei, Aaron M. Ring, Leying Guan, Charles Dela Cruz, Harlan M. Krumholz & Akiko Iwasaki
Shared TCRs in peripheral blood offer robust celiac disease classification independent of gluten intake
Rebecca Elyanow, et al.
bioRxiv
Pre-Print
December 2025
Authors and Affiliates
Rebecca Elyanow, Rok Seon Choung, Eric V. Marietta, Ramit Bharanikumar, Wenyu Zhou, Haiyin Chen-Harris, Bryan Howie, Harlan S Robins, Susan L. Neuhausen, Joseph A. Murray
HLA-A*03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis
Zhang BC, et al.
EBio Medicine
September 2025
Authors and Affiliates
Brian C. Zhang, Tilman Schneider-Hohendorf, Rebecca Elyanow, Beatrice Pignolet, Simon Falk, Christian Wünsch, Marie Deffner, Erik Yusko, Damon May, Daniel Mattox, Eva Dawin, Lisa Ann Gerdes, Florence Bucciarelli, Lisa Revie, Gisela Antony, Sven Jarius, Christiane Seidel, Makbule Senel, Stefan Bittner, Felix Luessi, Joachim Havla, Matthias Knop, Manuel A. Friese, Susanne Rothacher, Anke Salmen, Fumie Hayashi, Roland Henry, Stacy Caillier, Adam Santaniello, University of California San Francisco MS-EPIC Team, German Competence Network Multiple Sclerosis (KKNMS), Maria Seipelt, Christoph Heesen, Sandra Nischwitz, Antonios Bayas, Hayrettin Tumani, Florian Then Bergh, Gerd Meyer zu Hörste, Tania Kümpfel, Catharina C. Gross, Brigitte Wildemann, Martin Kerschensteiner, Ralf Gold, Sven G. Meuth, Frauke Zipp, Bruce A. C. Cree, Jorge Oksenberg, Michael R. Wilson, Stephen L. Hauser, Scott S. Zamvil, Luisa Klotz, Roland Liblau.
Longitudinal study of immunity to SARS-CoV2 inocrelizumab-treated MS patients up to 2 years after COVID-19 vaccination
Kister I., et al.
Annals of Clinical and Translational Neurology
August 2024
Authors and Affiliates
Ilya Kister, Ryan Curtin, Amanda L. Piquet, Tyler Borko, Jinglan Pei, Barbara L Banbury, Tamar E. Bacon, Angie Kim, Michael Tuen, Yogambigai Velmurugu, Samantha Nyovanie,
Sean Selva, Marie I. Samanovic, Mark J. Mulligan, Yury Patskovsky, Jessica Priest, Mark Cabatingan, Ryan C. Winger, Michelle Krogsgaard & Gregg J. Silverman
Broader anti-EBV TCR repertoire in multiple sclerosis: disease specificity and treatment modulation
Schneider-Hohendorf, et al.
Brain
July 2024
Authors and Affiliates
Tilman Schneider-Hohendorf, Christian Wünsch, Simon Falk, Catarina Raposo, Florian Rubelt, Hamid Mirebrahim, Hosseinali Asgharian, Ulrich Schlecht, Daniel Mattox, Wenyu Zhou, Eva Dawin, Marc Pawlitzki, Sarah Lauks, Sven Jarius, Brigitte Wildemann, Joachim Havla, Tania Kümpfel, Miriam-Carolina Schrot, Marius Ringelstein, Markus Kraemer, Carolin Schwake, Thomas Schmitter, Ilya Ayzenberg, Katinka Fischer, Sven G. Meuth, Orhan Aktas, Martin W. Hümmert, Julian R. Kretschmer, Corinna Trebst, Ilka Kleffner, Jennifer Massey, Paolo A. Muraro, Haiyin Chen-Harris, Catharina C. Gross, Luisa Klotz, Heinz Wiendl and Nicholas Schwab
Complete loss of TP53 and RB1 is associated with complex genome and low immune infiltrate in pleomorphic rhabdomyosarcoma
Authors and Affiliates
Hannah C. Beird; Chia-Chin Wu; Michael Nakazawa; Davis Ingram; Joseph R. Daniele; Rossana Lazcano; Latasha Little; Christopher Davies; Najat C. Daw; Khalida Wani; Wei-Lien Wang; Xingzhi Song; Curtis Gumbs; Jianhua Zhang; Brian Rubin; Anthony Conley; Adrienne M. Flanagan; Alexander J. Lazar and P. Andrew Futreal.
Locus folding mechanisms determine modes of antigen receptor gene assembly
Authors and Affiliates
Brittney M Allyn 1,2, Katharina E Hayer 2,3,4, Clement Oyeniran 5, Vincent Nganga 5, Kyutae Lee 2, Bikash Mishra 5, Ahmet Sacan 3, Eugene M Oltz 5, Craig H Bassing 1,2;
1 Immunology Graduate Group, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.
2 Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
3 Biomedical Engineering Doctoral Degree Program, School of Biomedical Engineering, Science and Health Systems, Drexel University , Philadelphia, PA, USA.
4 Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Perelman School of Medicine, Philadelphia, PA, USA.
5 Department of Microbial Infection and Immunity, Ohio State College of Medicine, Ohio State University, Columbus, OH, USA.
Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations
Authors and Affiliates
Šimon Borna 1, Esmond Lee 1,2, Jason Nideffer 1, Akshaya Ramachandran 1, Bing Wang 1, Jeanette Baker 3, Melissa Mavers 1, Uma Lakshmanan 1, Mansi Narula 1, Amy Kang-Hee Garrett 1, Janika Schulze 4, Sven Olek 5, Louis Marois 6, Yael Gernez 7, Monica Bhatia 8, Hey Jin Chong 9, Jolan Walter 10, Maleewan Kitcharoensakkul 11, Abigail Lang 12,13, Megan A Cooper 14, Alice Bertaina 1,15, Maria Grazia Roncarolo 1,2,15, Eric Meffre 16, Rosa Bacchetta 1,15;
1 Department of Pediatrics, Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
2 Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
3 Department of Medicine, Division of Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA 94305, USA.
4 Epimune GmbH, Berlin 12489, Germany.
5 Ivana Turbachova Laboratory for Epigenetics, Precision for Medicine GmbH, Berlin 12489, Germany.
6 Department of Medicine, Immunology and Allergy Service, CHU de Québec-Laval University, Quebec G1V 4G2, Canada.
7 Department of Pediatrics, Division of Allergy, Rheumatology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.
8 Columbia University Irving Medical Center, New York, NY 10032, USA.
9 Division of Allergy and Immunology, University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, Pittsburgh, PA 15224, USA.
10 Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins All Children's Hospital, University of South Florida, St. Petersburg, FL 33701, USA.
11 Divisions of Rheumatology/Immunology and Allergy and Pulmonary Medicine, Department of Pediatrics, Washington University in St. Louis, St. Louis, MO 63110, USA.
12 Department of Pediatrics, Division of Allergy and Immunology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
13 Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
14 Department of Pediatrics, Division of Rheumatology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA.
15 Center for Definitive and Curative Medicine (CDCM), Stanford University School of Medicine, Stanford, CA 94305, USA.
16 Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, 269 Campus Drive West, Stanford, CA 94305, USA.
Tracking DNA-based antigen-specific T cell receptors during progression to type 1 diabetes
Mitchell AM, et al.
Science Advances
December 2023
Authors and Affiliates
Angela M Mitchell 1, Erin E Baschal 1, Kristen A McDaniel 1, Theodore Fleury 1, Hyelin Choi 1, Laura Pyle 1,2, Liping Yu 1,3, Marian J Rewers 1,3,4, Maki Nakayama 1,3,5, Aaron W Michels 1,3,4,5;
1 Barbara Davis Center for Diabetes, University of Colorado School of Medicine, Aurora, CO, USA.
2 Department of Biostatistics and Informatics, University of Colorado School of Public Health, Aurora, CO, USA.
3 Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
4 Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
5 Department of Immunology, University of Colorado School of Medicine, Aurora, CO, USA.