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Tina Cascone 1, William N William Jr 2,3, Annikka Weissferdt 4,5, Cheuk H Leung 6, Heather Y Lin 6, Apar Pataer 5, Myrna C B Godoy 7, Brett W Carter 7, Lorenzo Federico 8, Alexandre Reuben 2, Md Abdul Wadud Khan 9, Hitoshi Dejima 10,11, Alejandro Francisco-Cruz 10, Edwin R Parra 10, Luisa M Solis 10, Junya Fujimoto 10, Hai T Tran 2, Neda Kalhor 4, Frank V Fossella 2, Frank E Mott 2, Anne S Tsao 2, George Blumenschein Jr 2, Xiuning Le 2, Jianjun Zhang 2, Ferdinandos Skoulidis 2, Jonathan M Kurie 2, Mehmet Altan 2, Charles Lu 2, Bonnie S Glisson 2, Lauren Averett Byers 2, Yasir Y Elamin 2, Reza J Mehran 5, David C Rice 5, Garrett L Walsh 5, Wayne L Hofstetter 5, Jack A Roth 5, Mara B Antonoff 5, Humam Kadara 10, Cara Haymaker 10, Chantale Bernatchez 8,10, Nadim J Ajami 12, Robert R Jenq 12,13,14, Padmanee Sharma 15,16, James P Allison 16, Andrew Futreal 12, Jennifer A Wargo 9, Ignacio I Wistuba 2,10, Stephen G Swisher 5, J Jack Lee 6, Don L Gibbons 2, Ara A Vaporciyan 5, John V Heymach #,2,17, Boris Sepesi #,5; 1 Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. tcascone@mdanderson.org. 2 Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 3 Oncology Center, Hospital BP, a Beneficencia Portuguesa de São Paulo, São Paulo, Brazil. 4 Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 5 Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 6 Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 7 Thoracic Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 8 Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 9 Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 10 Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 11 Teikyo University School of Medicine, Itabashi, Tokyo, Japan. 12 Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 13 Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 14 CPRIT Scholar in Cancer Research, Houston, TX, USA. 15 Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 16 Immunology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 17 Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. # Contributed equally.