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Generation of human memory stem T cells upon haploidentical T-replete hematopoietic stem cell transplantation

Cieri et al.
Blood Journal
Papers
March 2015
Authors and Affiliates
Cieri N1, Oliveira G1, Greco R2, Forcato M3, Taccioli C3, Cianciotti B1, Valtolina V1, Noviello M1, Vago L2, Bondanza A1, Lunghi F2, Marktel S2, Bellio L4, Bordignon C5, Bicciato S3, Peccatori J2, Ciceri F2, Bonini C1 Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious diseases, Program in Immunology and Bio-immunotherapy of Cancer (PIBIC), San Raffaele Scientific Institute, Milan, Italy1; Hematology and Bone Marrow Transplantation Unit, Department of Oncology, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan, Italy2; Center for Genome Research, Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy3; Unit of Molecular and Functional Immunogenetics, Division of Regenerative Medicine, Stem cells and Gene Therapy, San Raffaele Scientific Institute, Milan, Italy4; University Vita-Salute San Raffaele, Milan, Italy5

BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties

Haymaker et al.
OncoImmunology
Papers
March 2015
Authors and Affiliates
Haymaker CL1, Wu RC2, Ritthipichai K3, Bernatchez C4, Forget MA1, Chen JQ5, Liu H6, Wang E7, Marincola F8, Hwu P5,Radvanyi LG9. 1Department of Melanoma Medical Oncology; The University of Texas MD Anderson Cancer Center ; Houston, TX USA. 2Department of Melanoma Medical Oncology; The University of Texas MD Anderson Cancer Center ; Houston, TX USA ; MD/PhD Program; University of Texas Medical School at Houston ; Houston, TX USA ; Graduate Program in Immunology; University of Texas Graduate School of Biomedical Sciences ; Houston, TX USA ; University of Texas Southwestern Medical Center; Department of Internal Medicine ; Dallas, TX USA. 3Department of Melanoma Medical Oncology; The University of Texas MD Anderson Cancer Center ; Houston, TX USA ; Graduate Program in Immunology; University of Texas Graduate School of Biomedical Sciences ; Houston, TX USA. 4Department of Melanoma Medical Oncology; The University of Texas MD Anderson Cancer Center ; Houston, TX USA ; University of Texas Southwestern Medical Center; Department of Internal Medicine ; Dallas, TX USA. 5Department of Melanoma Medical Oncology; The University of Texas MD Anderson Cancer Center ; Houston, TX USA ; Lion Biotechnologies ; Tampa, FL USA. 6Infectious Disease and Immunogenetics Section; Department of Transfusion Medicine; Clinical Center and trans-NIH Center for Human Immunology; National Institutes of Health ; Bethesda, MD USA. 7Infectious Disease and Immunogenetics Section; Department of Transfusion Medicine; Clinical Center and trans-NIH Center for Human Immunology; National Institutes of Health ; Bethesda, MD USA ; Sidra Medical Research Hospital ; Doha, Qatar. 8Surgery Branch; National Cancer Institute; National Institutes of Health ; Bethesda, MD USA ; Department of Immunology; H Lee Moffitt Cancer Center ; Tampa, FL USA. 9Department of Melanoma Medical Oncology; The University of Texas MD Anderson Cancer Center ; Houston, TX USA ; Lion Biotechnologies ; Tampa, FL USA ; Department of Immunology; H Lee Moffitt Cancer Center ; Tampa, FL USA.

Immune Reconstitution / Immunocompetence in Recipients of Kidney Plus Hematopoietic Stem/Facilitating Cell Transplants

Leventhal et al.
Papers
Transplantation
February 2015
Authors and Affiliates
Leventhal JR1, Elliot MJ2, Yolcu ES2, Bozulic LD3, Tollerud DJ2, 3, Mathew JM1, Konieczna I1, Ison MG1, Galvin J1, Mehta J1, Badder MD2, Abecassis MMI1, Miller J1, Gallon L1, Ildstad ST2,3. 1Comprehensive Transplant Center, Northwestern Memorial Hospital, Chicago, IL; 2Institute for Cellular Therapeutics, University of Louisville, KY; 3Regenerex, LLC, Louisville, KY.

High Expression of CD26 Accurately Identified Human Bacterial-reactive MR1-restricted MAIT cells

Sharma et al.
Journal of Immunology
Papers
February 2015
Authors and Affiliates
Sharma PK1, Wong EB2,3, Napier RJ1, Bishai WR3,4, Ndung'u T2,3, Kasprowicz VO2,5,6, Lewinsohn DA7,9, Lewinsohn DM1,8,9, Gold MC1,8,9 Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, OR1; KwaZulu-Natal Research Institute for Tuberculosis and HIV, Durban, South Africa2; Division of Infections Diseases, Massachusetts General Hospital, Boston, MA3; Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, MD4; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA5; HIV Pathogenesis Programme, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, South Africa6; Pediatrics, Oregon Health & Science University, Portland OR7; Portland VA Medical Center, Portland, OR8; Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR9

Type II NKT-TFH cells against Gaucher lipids regulate B-cell immunity and inflammation

Nair et al.
Blood
Papers
February 2015
Authors and Affiliates
Nair S1, Boddupalli CS1, Verma R1, Liu J2, Yang R2, Pastores GM3, Mistry PK4, Dhodapkar MV5 1Section of Hematology and 2Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, New Haven, CT; 3Department of Neurology and Pediatrics, New York University School of Medicine, New York, NY; and. 4Section of Digestive Diseases, Department of Medicine, Yale University School of Medicine, New Haven, CT; Yale Liver Center and. 5Section of Hematology and Yale Cancer Center, Yale University School of Medicine, New Haven, CT.

T-Cell Receptor Sequencing Reveals the Clonal Diversity and Overlap of Colonic Effector and FOXP3+ T Cells in Ulcerative Colitis

Lord et al.
Inflamm Bowel Dis
Papers
January 2015
Authors and Affiliates
Lord J1,2, Chen J1, Thirlby RC3, Sherwood AM4, Carlson CS4,5 Translational Research Program, Benaroya Research Institute at Virginia Mason, Seattle, WA1; Departments of Gasterenterology2 and Surgery3, Virginia Mason Medical Center, Seattle, WA; Adaptive Biotechnologies, Seattle, WA4; Fred Hutchinton Cancer Research Center, Seattle, WA5

Polyclonal, newly derived T cells with low expression of inhibitory molecule PD-1 in tonsils define the phenotype of lymphocytes in children with Periodic Fever, Aphtous Stomatitis, Pharyngitis and Adenitis (PFAPA) syndrome

Dytrych et al.
Molecular Immunology
Papers
January 2015
Authors and Affiliates
Dytrych P1, Krol P2, Kotrova M3, Kuzilkova D3, Hubacek P3,4, Krol L3, Katra R1, Hrusak O3, Kabelka Z1, Dolezalova P2, Kalina T3, Fronkova E3 Department of ENT, Charles University, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Czech Republic1; Pediatric Rheumatology Unit, Department of Pediatrics and Adolescent Medicine, Charles University Prague and General University Hospital in Prague, 1st Faculty of Medicine, Czech Republic2; CLIP, Department of Paediatric Haematology/Oncology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol Czech Republic3; Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Czech Republic4

The Analysis Of Clonal Diversity And Therapy Responses Using STAT3 Mutations As A Molecular Marker In Large Granular Lymphocytic Leukemia

Rajala et al.
Haematologica
Papers
January 2015
Authors and Affiliates
Rajala HL1, Olson T2, Clemente MJ3, Lagström S4, Ellonen P4, Lundan T5, Hamm DE6, Zaman SA4, Lopez Marti JM4,Andersson EI1, Jerez A7, Porkka K1, Maciejewski JP3, Loughran TP2, Mustjoki S8. 1Hematology Research Unit, Department of Hematology, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland. 2University of Virginia Cancer Center, Charlottesville, VA, USA. 3Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA. 4Institute for Molecular Medicine (FIMM), University of Helsinki, Finland. 5Department of Clinical Chemistry and TYKSLAB, University of Turku and Turku University Central Hospital, Finland. 6Adaptive Biotechnologies Corp, Seattle, WA, USA. 7Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA Hematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, Universidad de Murcia, IMIB-Arrixaca, Murcia, Spain. 8Hematology Research Unit, Department of Hematology, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland