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CTLA4 blockade broadens the peripheral T-cell receptor repertoire

Robert et al.
Clinical Cancer Research
Papers
May 2014
Authors and Affiliates
Lidia Robert,1 Jennifer Tsoi,2 Xiaoyan Wang,1,3 Ryan Emerson,7,8 Blanca Homet,1,9 Thinle Chodon,1 Stephen Mok,1,2Rong Rong Huang,4 Alistair J. Cochran,4 Begonya Comin-Anduix,5,6 Richard C. Koya,4,6 Thomas G. Graeber,2,6 Harlan Robins,7,8 and Antoni Ribas1,2,4,6 1Department of Medicine (Division of Hematology-Oncology), University of California Los Angeles (UCLA), 2Department of Molecular and Medical Pharmacology, University of California Los Angeles (UCLA), 3Department of Medicine (Statistics core), University of California Los Angeles (UCLA), 4Department of Pathology and Laboratory Medicine, University of California Los Angeles (UCLA), 5Department of Surgery (Division of Surgical-Oncology), University of California Los Angeles (UCLA), 6Jonsson Comprehensive Cancer Center (JCCC), University of California Los Angeles (UCLA), 7Fred Hutchinson Cancer Research Center, Seattle, WA, 8Adaptive Biotechnologies, Seattle, WA, 9Instituto de Salud Carlos III, Madrid, Spain

Quantifying selection in immune receptor repertoires

Elhanati et al.
Cornell University Library
Papers
April 2014
Authors and Affiliates
Yuval Elhanati,a Anand Murugan,b Curtis G. Callan, Jr.c, Thierry Mora,d and Aleksandra M. Walczaka aLaboratoire de Physique Théorique, Unité Mixte de Recherche 8549, dLaboratoire de Physique Statistique, Unité Mixte de Recherche 8550, Centre National de la Recherche Scientifique and École Normale Supérieure, 75005 Paris, France, bDepartment of Applied Physics, Stanford University, Stanford, CA, 94305; and, cJoseph Henry Laboratories, Princeton University, Princeton, NJ, 08544.

Novel GMP-compatible protocol employing an allogeneic B cell bank for clonal expansion of allospecific natural regulatory T cells

Landwehr-Kenzel et al.
American Journal of Transplantation
Papers
February 2014
Authors and Affiliates
S. Landwehr-Kenzel1,2,3,*, F. Issa4, S.-H. Luu1,2,5, M. Schmück1,6, H. Lei1,2,6, A. Zobel1, A. Thiel1, N. Babel1,5, K. Wood4, H.-D. Volk1,6 and P. Reinke1,5 1Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany, 2Berlin-Brandenburg School for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany, 3Department of Pediatric Pulmonology and Immunology, Charité University Medicine Berlin, Berlin, Germany, 4Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Oxford, United Kingdom, 5Renal and Transplant Research Unit, Department of Nephrology and Internal Intensive Care, Charité University Medicine Berlin, Berlin, Germany, 6Institute of Medical Immunology, Charité University Medicine Berlin, Berlin, Germany.

T cell repertoire following autologous stem cell transplantation for multiple sclerosis

Muraro et al.
JCI
Papers
February 2014
Authors and Affiliates
Paolo A. Muraro,1 Harlan Robins,2 Sachin Malhotra,3 Michael Howell,3 Deborah Phippard,3 Cindy Desmarais,4 Alessandra de Paula Alves Sousa,1 Linda M. Griffith,5 Noha Lim,3 Richard A. Nash,6 and Laurence A. Turka3,7 1Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom. 2Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. 3Immune Tolerance Network, Bethesda, Maryland, USA. 4Adaptive Biotechnologies, Seattle, Washington, USA. 5Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA. 6Colorado Blood Cancer Institute at PSL, Denver, Colorado, USA. 7Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Intramuscular Therapeutic Vaccination Targeting HPV16 Induces T Cell Responses That Localize in Mucosal Lesions

Maldonado et al.
Papers
Science Translational Medicine
January 2014
Authors and Affiliates
Maldonado L1*, Teague JE2*, Morrow MP3*, Jotova I4, Wu TC5, Wang C6, Desmarais C7, Boyer JD8, Tycko B4, Robins HS9, Clark RA2, Trimble CL1,5,10 1 Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. 2 Harvard Skin Disease Research Center and the Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115, USA. 3 Inovio Pharmaceuticals Inc., 1787 Sentry Parkway West, Building 18, Suite 400, Blue Bell, PA 19422, USA. 4 Department of Pathology and Cell Biology and Institute for Cancer Genetics, Columbia University Medical Center, New York, NY 10025, USA. 5 Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. 6 Oncology Biostatistics, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. 7 Adaptive Biotechnologies, 1551 Eastlake Avenue, Seattle, WA 98102, USA. 8 Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. 9 Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. 10 Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. * Contributed equally

Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I

Chapuis et al.
Cancer Immunology Research
Papers
January 2014
Authors and Affiliates
Chapuis AG1, Afanasiev OK2, Iyer JG3, Paulson KG2, Parvathaneni U4, Hwang JH5, Lai I1, Roberts IM1, Sloan HL1, Bhatia S6, Shibuya KC1, Gooley T1, Desmarais C7, Koelle DM8, Yee C1, Nghiem P2. 1Program in Immunology, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, WA, USA, 2Department of Pathology, University of Washington, Seattle, WA, USA ; Department of Medicine (Dermatology), University of Washington, Seattle, WA, USA, 3Department of Medicine (Dermatology), University of Washington, Seattle, WA, USA, 4Division of Radiation Oncology, UWMC, Seattle, WA, USA, 5Division of Gastroenterology, UWMC, Seattle, WA, USA, 6Department of Medicine (Medical Oncology), University of Washington, Seattle, WA, USA, 7Adaptive Biotechnologies, Seattle, WA, USA, 8Department of Medicine (Dermatology), University of Washington, Seattle, WA, USA ; Department of Laboratory Medicine, University of Washington, Seattle, WA, USA ; Department of Global Health, University of Washington, Seattle, WA, USA ; Vaccine and Infectious Disease Division, FHCRC, Seattle, WA, USA ; Benaroya Research Institute, Seattle, WA, USA.

Tumor-Associated Immune Parameters for Personalized Patient Care

Pagès
Papers
Science Translational Medicine
December 2013
Authors and Affiliates
Franck Pagès Laboratory of Immunology, Immunomonitoring Platform, Georges Pompidou European Hospital, AP-HP, Paris Descartes University, Laboratory of Integrative Cancer Immunology, INSERM U872, Cordeliers Research Center, Paris, France.

Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation

Jones et al.
Papers
Proceedings of the National Academy of Sciences
December 2013
Authors and Affiliates
Joanne L. Jonesa, 1, Sara A. J. Thompsona, Priscilla Lohb, Jessica L. Daviesa, Orla C. Tuohya, Allison J. Currya, Laura Azzopardia, Grant Hill-Cawthornea,c, Michael T. Faheyb,d, Alastair Compstona, and Alasdair J. Colesa. a Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, United Kingdom; b Division of Mathematics, Informatics and Statistics, Commonwealth Scientific and Industrial Research Organization, Clayton South, VIC 3169, Australia; c Sydney Institute for Emerging Infections and Biosecurity, University of Sydney, Sydney, NSW 2006, Australia; and d Biostatistics Unit, Monash University, Melbourne, VIC 3004 Australia.
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