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Characterization of human T cell receptor repertoire data in eight thymus samples and four related blood samples
Heikkilä N., et al.
Data in Brief
January 2021
Authors and Affiliates
Nelli Heikkilä 1,2, Iivari Kleino 1, Reetta Vanhanen 1,2, Dawit A. Yohannes 1,3, Ilkka P. Mattila 4, Jari Saramäki 5, T. Petteri Arstila 1,2;
1 Research Programs Unit, Translational Immunology, University of Helsinki, Haartmaninkatu 3, 00290 Helsinki, Finland
2 Medicum, Department of Bacteriology and Immunology, University of Helsinki, Haartmaninkatu 3, 00290 Helsinki, Finland
3 Department of Medical and Clinical Genetics, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki
4 Department of Pediatric Cardiac and Transplantation Surgery, Hospital for Children and Adolescents, Helsinki University Central Hospital, Stenbäckinkatu 9, 00290 Helsinki, Finland
5 Department of Computer Science, Aalto University, Konemiehentie 2, 02150 Espoo, Finland
CDR3 and V genes show distinct reconstitution patterns in T cell repertoire post-allogeneic bone marrow transplantation
Tickotsky-Moskovitz N., et al.
Immunogenetics
January 2021
Authors and Affiliates
Nili Tickotsky-Moskovitz 1, Yoram Louzoun 2, Shirit Dvorkin 3, Adi Rotkopf 4, Amir Asher Kuperman 4,5, Sol Efroni 1;
1 The Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel.
2 Department of Mathematics, Bar Ilan University, Ramat Gan, Israel. louzouy@math.biu.ac.il.
3 Department of Mathematics, Bar Ilan University, Ramat Gan, Israel.
4 Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
5 Blood Coagulation Service and Pediatric Hematology Clinic, Galilee Medical Center, Nahariya, Israel.
Characterization of ascites- and tumor-infiltrating γδ T cells reveals distinct repertoires and a beneficial role in ovarian cancer
Foord E., et al.
Science Translational Medicine
January 2021
Authors and Affiliates
Emelie Foord 1, Lucas C M Arruda 2, Ahmed Gaballa 2,3, Charlotte Klynning 4, Michael Uhlin 2,5,6;
1 Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 171 77 Stockholm, Sweden. emelie.foord@ki.se.
2 Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 171 77 Stockholm, Sweden.
3 Department of Clinical Biochemistry, National Liver Institute, Menoufia University, 511 32 Shebin Elkom, Egypt.
4 Department of Gynecological Oncology, Karolinska University Hospital, 171 76 Stockholm, Sweden.
5 Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, 141 86 Stockholm, Sweden.
6 Department of Applied Physics, Royal Institute of Technology, 100 44 Stockholm, Sweden.
The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse
Singhania A., et al.
Scientific Reports
January 2021
Authors and Affiliates
Akul Singhania 1, John Pham 1, Rekha Dhanwani 1, April Frazier 1, Juliana Rezende Dutra 2, Karen S Marder 2, Elizabeth Phillips 3,4, Simon Mallal 3,4, Amy W Amara 5, David G Standaert 5, David Sulzer 2,6,7, Bjoern Peters 1,8, Alessandro Sette 1,8, Cecilia S Lindestam Arlehamn 9;
1 Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
2 Department of Neurology, Columbia University Medical Center, New York, NY, 10032, USA.
3 Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, 6150, Australia.
4 Vanderbilt University School of Medicine, Nashville, TN, 37235, USA.
5 Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, 35233, USA.
6 Department of Psychiatry, Columbia University Medical Center, New York, NY, 10032, USA.
7 Department of Pharmacology, Columbia University Medical Center, New York, NY, 10032, USA.
8 Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.
9 Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA. cecilia@lji.org.
Distinct T cell receptor repertoire diversity of clinically defined high-grade serous ovarian cancer treatment subgroups
Lee S., et al.
iScience
January 2021
Authors and Affiliates
Sanghoon Lee 1, Li Zhao 2, Latasha D. Little 2, Shannon N. Westin 3, Amir A. Jazarei 3, Nicole D. Fleming 3, Jianhua Zhang 2, P. Andrew Futreal 2, Anil K. Sood 3;
1 Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
2 Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
3 Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Necrotizing enterocolitis induces T lymphocyte-mediated injury in the developing mammalian brain
Zhou Q., et al.
Science Translational Medicine
January 2021
Authors and Affiliates
Qinjie Zhou 1,2, Diego F Niño 1,2, Yukihiro Yamaguchi 1,2, Sanxia Wang 1,2, William B Fulton 1,2, Hongpeng Jia 1,2, Peng Lu 1,2, Thomas Prindle Jr 1,2, David Pamies 3,4, Meaghan Morris 5, Liam L Chen 4, Chhinder P Sodhi 6,2, David J Hackam 6,2;
1 Division of General Pediatric Surgery, Johns Hopkins University and Bloomberg Children's Center, Johns Hopkins Hospital, Baltimore, MD, USA.
2 Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
3 Center for Alternatives to Animal Testing, Johns Hopkins School of Public Health, Baltimore, MD, USA.
4 Department of Biomedical Science, University of Lausanne, Lausanne, Switzerland.
5 Division of Neuropathology, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
6 Division of General Pediatric Surgery, Johns Hopkins University and Bloomberg Children's Center, Johns Hopkins Hospital, Baltimore, MD, USA. dhackam1@jhmi.edu csodhi@jhmi.edu.
Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination
Yu J., et al.
Nature Medicine
January 2021
Authors and Affiliates
Jiali Yu 1,2, Michael D Green 3,4,5, Shasha Li 1,2,6, Yilun Sun 7,8, Sara N Journey 9, Jae Eun Choi 10,11, Syed Monem Rizvi 12, Angel Qin 13, Jessica J Waninger 9,11, Xueting Lang 1,2, Zoey Chopra 9, Issam El Naqa 7,14, Jiajia Zhou 1,2, Yingjie Bian 1,2, Long Jiang 2,7, Alangoya Tezel 9, Jeremy Skvarce 9, Rohan K Achar 9,15, Merna Sitto 7, Benjamin S Rosen 7, Fengyun Su 10,11, Sathiya P Narayanan 10,11, Xuhong Cao 10,11,16, Shuang Wei 1,2, Wojciech Szeliga 1,2, Linda Vatan 1,2, Charles Mayo 7, Meredith A Morgan 7, Caitlin A Schonewolf 7, Kyle Cuneo 7, Ilona Kryczek 1,2, Vincent T Ma 13, Christopher D Lao 13, Theodore S Lawrence 7, Nithya Ramnath 17,13, Fei Wen 12, Arul M Chinnaiyan 10,11,16, Marcin Cieslik 6,10,11, Ajjai Alva 2,13, Weiping Zou 18,19,20,21,22;
1 Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
2 Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, Ann Arbor, MI, USA.
3 Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, Ann Arbor, MI, USA. migr@med.umich.edu.
4 Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA. migr@med.umich.edu.
5 Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, USA. migr@med.umich.edu.
6 Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
7 Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
8 Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
9 University of Michigan Medical School, University of Michigan, Ann Arbor, MI, USA.
10 Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
11 Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA.
12 Chemical Engineering, University of Michigan, Ann Arbor, MI, USA.
13 Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
14 Machine Learning Department, Moffitt Cancer Center, Tampa, FL, USA.
15 University of Michigan School of Public Health, Ann Arbor, MI, USA.
16 Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI, USA.
17 Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, USA.
18 Department of Surgery, University of Michigan, Ann Arbor, MI, USA. wzou@med.umich.edu.
19 Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, Ann Arbor, MI, USA. wzou@med.umich.edu.
20 Department of Pathology, University of Michigan, Ann Arbor, MI, USA. wzou@med.umich.edu.
21 Graduate Program in Immunology, University of Michigan Medical School, Ann Arbor, MI, USA. wzou@med.umich.edu.
22 Graduate Program in Cancer Biology, University of Michigan Medical School, University of Michigan, Ann Arbor, MI, USA. wzou@med.umich.edu.
Image guided lymph node core needle biopsy predicts survival in mycosis fungoides and Sézary syndrome
Calvani J., et al.
British Journal of Dermatology
January 2021
Authors and Affiliates
J Calvani 1, A de Masson 2,3, C de Margerie-Mellon 4, É de Kerviler 4, C Ram-Wolff 2,3, A Gruber 3,5, V Meignin 1, P Brice 6, A Sadoux 5, S Mourah 3,5, M Bagot 2,3, Maxime Battistella 1,3;
1 Pathology Department, Assistance Publique Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France.
2 Dermatology Department, Assistance Publique Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France.
3 INSERM UMR-S976, Université de Paris, Paris, France.
4 Radiology Department, Assistance Publique Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France.
5 Solid tumor genomics Department, Assistance Publique Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France.
6 Hematology Department, Assistance Publique Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France.
Safety and efficacy of consolidation therapy with ipilimumab plus nivolumab after autologous stem cell transplantation
Skarbnik AP, et al.
January 2021
Authors and Affiliates
Alan P Skarbnik 1,2, Michele L Donato 1,3, Rena Feinman 3,4, Scott D Rowley 1,3, David H Vesole 1,3, Andre H Goy 1,3, Pashna N Munshi 3,5, Tatyana Feldman 1,3, Lori A Leslie 1,3, Noa Biran 1,3, Themba Nyirenda 1, Paul A Fields 6, Dante Descalzi-Montoya 4, Joshua Zenreich 1, Robert Korngold 3,4 and Andrew L Pecora 1,3;
1 John Theurer Cancer Center at Hackensack University Medical Center, NJ, USA
2 Novant Health Cancer Institute, NC, USA
3 Consortium Member Georgetown Lombardi Comprehensive Cancer Center
4 Center for Discovery and Innovation at Hackensack Meridian Health, NJ, US
5 Georgetown University Medical Center, DC, USA
6 Adaptive Biotechnologies, WA, USA