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IL-25/IL-33–responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa

Lam et al.
Papers
The Journal of Allergy and Clinical Immunology
December 2015
Authors and Affiliates
Emily P. S. Lam, PhD,1,8 Harsha H. Kariyawasam, FRCP, PhD,2,8 Batika M. J. Rana, PhD,3,8 Stephen R. Durham, MD, FRCP,4,8 Andrew N. J. McKenzie, PhD,3 Nicholas Powell, MRCP, PhD,5 Nara Orban, MD,4 Melissa Lennartz-Walker, MSc,1,8 Claire Hopkins, FRCS (ORL-HNS),7 Sun Ying, MD, PhD,1 Joanne Rimmer, FRCS (ORL-HNS),2 Valerie J. Lund, MD, FRCS,2 David J. Cousins, PhD,5,8 and Stephen J. Till, FRCP, PhD1,8 1The Division of Asthma, Allergy and Lung Biology, Guy’s Hospital, King’s College London; 2the Allergy and Medical Rhinology Section, Royal National Throat Nose Ear Hospital, University College London; 3the Medical Research Council Laboratory of Molecular Biology, Cambridge; 4the Section of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London; 5the Division of Transplantation Immunology and Mucosal Biology and Medical Research Council Centre for Transplantation, King’s College London; 6the Department of Infection, Immunity and Inflammation, NIHR Leicester Respiratory Biomedical Research Unit, Leicester Institute for Lung Health, University of Leicester; 7the Department of ENT, Guy’s and St Thomas’ Hospital, London; and 8the Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, London.

The Evolution of Tumors in Mice and Humans with Germline p53 Mutations

Levine, AJ
Cold Spring Harbor Symposia on Quantitative Biology
December 2015
Authors and Affiliates
Levine AJ1, Chan CS2, Dudgeon C3, Puzio-Kuter A3, Hainaut P4. 1Institute for Advanced Study, Princeton, New Jersey 08540 Cancer Institute of New Jersey, New Brunswick, New Jersey 08903 2Cancer Institute of New Jersey, New Brunswick, New Jersey 08903 Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Jersey 08903. 3Cancer Institute of New Jersey, New Brunswick, New Jersey 08903. 4Grenoble Institute for Research on Cancer, Grenoble 38706, France.

Targeting of HPV-16+ Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6

Lindsey M. Draper
Clinical Cancer Research
Papers
December 2015
Authors and Affiliates
Lindsey M. Draper1, Mei Li M. Kwong1, Alena Gros1, Sanja Stevanovic1, Eric Tran1, Sid Kerkar2, Mark Raffeld2, Steven A. Rosenberg1, and Christian S. Hinrichs1 1 Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. 2 Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland

Immunogenicity of somatic mutations in human gastrointestinal cancers.

Tran et al.
Papers
Science
December 2015
Authors and Affiliates
Tran E1, Ahmadzadeh M1, Lu YC1, Gros A1, Turcotte S1, Robbins PF1, Gartner JJ1, Zheng Z1, Li YF1, Ray S1, Wunderlich JR1, Somerville RP1, Rosenberg SA2. 1Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. 2Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Bi-Allelic TCRα or β Recombination Enhances T Cell Development but Is Dispensable for Antigen Responses and Experimental Autoimmune Encephalomyelitis

Shuldt et al.
Papers
PLOS ONE
December 2015
Authors and Affiliates
Nathaniel J. Schuldt1,3, Jennifer L. Auger1,3, Kristin A. Hogquist1,2,3, Bryce A. Binstadt1,3 1Departments of Pediatrics, University of Minnesota, Minneapolis, United States of America, 2Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, United States of America, 3Center for Immunology, University of Minnesota, Minneapolis, United States of America

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

Jeffrey A. Bluestone
Papers
Science Translational Medicine
November 2015
Authors and Affiliates
Jeffrey A. Bluestone1, Jane H. Buckner2, Mark Fitch3, Stephen E. Gitelman4, Shipra Gupta2, Marc K. Hellerstein3, Kevan C. Herold5, Angela Lares1, Michael R. Lee1, Kelvin Li6, Weihong Liu1, S. Alice Long2, Lisa M. Masiello1, Vinh Nguyen7, Amy L. Putnam1, Mary Rieck1, Peter H. Sayre8 and Qizhi Tang7 1 Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. 2 Translational Research Program, Benaroya Research Institute at Virginia Mason, Seattle, WA 98101, USA. 3 Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA. 4 Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143, USA. 5 Departments of Immunobiology and Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. 6 KineMed Inc., Emeryville, CA 94608, USA. 7 Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA. 8 Division of Hematology-Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

IL-21-driven neoplasms in SJL mice mimic some key features of human angioimmunoblastic T-cell lymphoma

Jain et al.
American Journal of Pathology
Papers
November 2015
Authors and Affiliates
Jain S1, Chen J2, Nicolae A3, Wang H1, Shin DM4, Adkins EB5, Sproule TJ6, Leeth CM7, Sakai T1, Kovalchuk AL1, Raffeld M3,Ward JM1, Rehg JE8, Waldmann TA2, Jaffe ES3, Roopenian DC5, Morse HC 3rd9. 1Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, Rockville, Maryland. 2Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. 3Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. 4Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, Rockville, Maryland; Department of Food and Nutrition, Seoul National University, Seoul, Republic of Korea. 5Jackson Laboratory, Bar Harbor, Maine; Genetics Program, Tufts University Sackler School of Graduate Biomedical Sciences, Boston, Massachusetts. 6Jackson Laboratory, Bar Harbor, Maine. 7Genetics Program, Tufts University Sackler School of Graduate Biomedical Sciences, Boston, Massachusetts; Department of Animal and Poultry Sciences, College of Agriculture and Life Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia. 8Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee. 9Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, Rockville, Maryland
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