Browse our 650+ Publications​

Latest Publications

Intrathecal BCR transcriptome in multiple sclerosis versus other neuroinflammation: Equally diverse and compartmentalized, but more mutated, biased and overlapping with the proteome

Johansen et al.
Clinical Immunology
Papers
October 2015
Authors and Affiliates
Johansen JN1, Vartdal F2, Desmarais C3, Tutturen AE4, de Souza GA5, Lossius A6, Holmøy T7. 1Department of Immunology and Transfusion Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway. 2Department of Immunology and Transfusion Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. 3Adaptive Biotechnologies, Seattle, WA, USA. 4Centre for Immune Regulation, Department of Immunology and Transfusion Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway. 5Centre for Immune Regulation, Department of Immunology and Transfusion Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway; Centre for Immune Regulation, Department of Immunology, University of Oslo, Oslo, Norway. 6Department of Immunology and Transfusion Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Neurology, Oslo University Hospital Rikshospitalet, Oslo, Norway. Electronic address: andreas.lossius@rr-research.no. 7Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Neurology, Akershus University Hospital, Lørenskog, Norway.

The difficult–and often delayed–diagnosis of CTCL

Weed et al.
Papers
Science Translational Medicine Editorial
October 2015
Authors and Affiliates
Weed J1, Girardi M1 1Department of Dermatology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.

T-cell receptor profiling in cancer

Kirsch et al.
Molecular Oncology
Papers
September 2015
Authors and Affiliates
Kirsch I1, Vignali M2, Robins H3. 1Adaptive Biotechnologies, Seattle, WA, USA. 2Adaptive Biotechnologies, Seattle, WA, USA. 3Adaptive Biotechnologies, Seattle, WA, USA; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Central role of Th2/Tc2 lymphocytes in pattern II multiple sclerosis lesions.

Planas et al.
Annals of Clinical and Translational Neurology
Papers
September 2015
Authors and Affiliates
Planas R1, Metz I2, Ortiz Y1, Vilarrasa N1, Jelčić I1, Salinas-Riester G3, Heesen C4, Brück W2, Martin R1, Sospedra M1. 1Neuroimmunology and MS Research (nims), Department of Neurology, University Zurich Frauenklinikstrasse 26, 8091, Zürich, Switzerland. 2Institute of Neuropathology, University Medical Center Göttingen Göttingen, Germany. 3Department of Developmental Biochemistry, DNA Microarray and Deep-Sequencing Facility, Faculty of Medicine, University Medical Center Göttingen Göttingen, Germany. 4Institute for Neuroimmunology and Clinical MS Research (inims), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf Falkenried 94, 20251, Hamburg, Germany.

High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires

Liaskou et al.
Hepatology
Papers
September 2015
Authors and Affiliates
Liaskou E1, Henriksen EK2,3,4, Holm K2,3,4, Kaveh F5, Hamm D6, Fear J1, Viken MK7, Hov JR2,3,4,8, Melum E2,3,4, Robins H9, Olweus J4,10,11, Karlsen TH2,3,4,8, Hirschfield GM1. 1Centre for Liver Research, National Institute for Health Research Birmingham Liver Biomedical Research Unit, University of Birmingham, Birmingham, UK. 2Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Cancer Medicine, Surgery, and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway. 3Research Institute of Internal Medicine, Division of Cancer Medicine, Surgery, and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway. 4K.G. Jebsen Inflammation Research Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. 5Department of Medical Genetics, Oslo University Hospital, Oslo, Norway. 6Adaptive Biotechnologies Corp., Seattle, WA. 7Institute of Immunology, Oslo University Hospital Rikshospitalet, Oslo, Norway. 8Section of Gastroenterology, Department of Transplantation Medicine, Division of Cancer Medicine, Surgery, and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway. 9Fred Hutchinson Cancer Research Center, Seattle, WA. 10Department of Immunology, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, Oslo, Norway. 11K.G. Jebsen Center for Cancer Immunotherapy, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

High-throughput sequencing reveals an altered T cell repertoire in X-linked agammaglobulinemia

Ramesh et al.
Clinical Immunology
Papers
September 2015
Authors and Affiliates
Ramesh M1, Simchoni N2, Hamm D3, Cunningham-Rundles C4. 1Montefiore Medical Center, Bronx, NY, United States. 2Icahn School of Medicine at Mount Sinai, New York, NY, United States. 3Adaptive Biotech, Seattle, WA, United States. 4Icahn School of Medicine at Mount Sinai, New York, NY, United States; Department of Pediatrics, The Immunology Institute, Box 1089, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, United States.

Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome

Kolhatkar et al.
Journal of Experimental Medicine
Papers
September 2015
Authors and Affiliates
Kolhatkar NS1, Brahmandam A2, Thouvenel CD2, Becker-Herman S2, Jacobs HM2, Schwartz MA1, Allenspach EJ1, Khim S2,Panigrahi AK3, Luning Prak ET3, Thrasher AJ4, Notarangelo LD5, Candotti F6, Torgerson TR2, Sanz I7, Rawlings DJ8. 1Department of Immunology and Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195. 2Department of Immunology and Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195 Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101. 3Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104. 4Molecular Immunology Unit, Section of Molecular and Cellular Immunology, Centre for Immunodeficiency, University College London Institute of Child Health, London WC1N 1EH, England, UK. 5Department of Immunology, Children's Hospital Boston, Boston, MA 09210. 6Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892. 7Lowance Center for Human Immunology and Division of Rheumatology, Department of Medicine, Emory University, Atlanta, GA 30322 Lowance Center for Human Immunology and Division of Rheumatology, Department of Medicine, Emory University, Atlanta, GA 30322. 8Department of Immunology and Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195 Department of Immunology and Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98195 Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101

High-throughput pairing of T cell receptor α and β sequences

Howie et al.
Papers
Science Translational Medicine
August 2015
Authors and Affiliates
Bryan Howie,1 Anna M. Sherwood,1 Ashley D. Berkebile,1 Jan Berka,1 Ryan O. Emerson,1 David W. Williamson,1 Ilan Kirsch,1 Marissa Vignali,1 Mark J. Rieder,1 Christopher S. Carlson,2 Harlan S. Robins1,2 1Adaptive Biotechnologies, Seattle, WA 98102, USA. 2Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Detection and Tracking of NY-ESO-1-Specific CD8+ T Cells by High-Throughput T Cell Receptor β (TCRB) Gene Rearrangements Sequencing in a Peptide-Vaccinated Patient.

Miyai et al.
Papers
PLOS ONE
August 2015
Authors and Affiliates
Miyai M1, Eikawa S2, Hosoi A1, Iino T1, Matsushita H1, Isobe M3, Uenaka A3, Udono H2, Nakajima J4, Nakayama E3, Kakimi K1. 1Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan. 2Department of Immunology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama, Japan. 3Faculty of Health and Welfare, Kawasaki University of Medical Welfare, Kurashiki, Okayama, Japan. 4Department of Thoracic Surgery, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.