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PD-1 blockade induces responses by inhibiting adaptive immune resistance
Tumeh et al.
Nature
Papers
November 2014
Authors and Affiliates
Tumeh PC1, Harview CL2, Yearley JH3, Shintaku IP2, Taylor EJ2, Robert L2, Chmielowski B1, Spasic M2, Henry G2, Ciobanu V2, West AN2, Carmona M2, Kivork C2, Seja E2, Cherry G2, Gutierrez AJ2, Grogan TR2, Mateus C4, Tomasic G4, Glaspy JA1, Emerson RO5, Robins H6, Pierce RH3, Elashoff DA1, Robert C4, Ribas A1.
1University of California Los Angeles (UCLA), Los Angeles, California 90095, USA [2] Jonsson Comprehensive Cancer Center, Los Angeles, California 90095, USA.
2University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
3Merck &Co, Palo Alto, California 94304, USA.
4Gustave Roussy and INSERM U981, Villejuif, Paris Sud, France.
5Adaptive Biotechnologies, Seattle, Washington 98102, USA.
6Adaptive Biotechnologies, Seattle, Washington 98102, USA [2] Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
Islet-Associated T-Cell Receptor-B CDR Sequence Repertoire in Prediabetic NOD Mice Reveals Antigen-Driven T-Cell Expansion And Shared Usage of VBJB TCR Chains
Toivonen et al.
Molecular Immunology
Papers
November 2014
Authors and Affiliates
Toivonen R1, Arstila TP2, Hanninen A1
Department of Medical Microbiology and Immunology, University of Turku, Turku, Finland1; Haartman Institute and Research Programs Unit, Immunobiology, University of Helsinki, Helsinki, Finland2
Spatial map of human T cell compartmentalization and maintenance over decades of life
Thome et al.
Cell
Papers
November 2014
Authors and Affiliates
Thome JJ1, Yudanin N1, Ohmura Y2, Kubota M2, Grinshpun B3, Sathaliyawala T4, Kato T2, Lerner H5, Shen Y3, Farber DL6
1Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY 10032, USA; Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA. 2Department of Surgery, Columbia University Medical Center, New York, NY 10032, USA. 3Department of Systems Biology and Biomedical Informatics, and the JP Sulzberger Columbia Genome Center, Columbia University, New York, NY 10032, USA. 4Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY 10032, USA. 5The New York Organ Donor Network (NYODN), New York, NY 10001, USA. 6Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY 10032, USA; Department of Surgery, Columbia University Medical Center, New York, NY 10032, USA; Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address: df2396@cumc.columbia.edu.
Defining the alloreactive T cell repertoire using high-throughput sequencing of mixed lymphocyte reaction culture.
Emerson et al.
Papers
PLOS ONE
November 2014
Authors and Affiliates
Emerson RO1, Mathew JM2, Konieczna IM3, Robins HS4, Leventhal JR3.
1Adaptive Biotechnologies Corporation, Seattle, Washington, United States of America.
2Department of Surgery, Comprehensive Transplant center, Northwestern University, Chicago, Illinois, United States of America; Department of Microbiology-Immunology, Northwestern University, Chicago, Illinois, United States of America.
3Department of Surgery, Comprehensive Transplant center, Northwestern University, Chicago, Illinois, United States of America.
4Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells
Iijima et al.
Papers
Science
October 2014
Authors and Affiliates
Iijima N1 and Iwasaki A2
Howard Hughes Medical Institute and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
The Evolution of Thymic Lymphomas in P53 Knockout Mice
Dudgeon et al.
Genes & Development
Papers
October 2014
Authors and Affiliates
Dudgeon C1,6, Chan C1,2,6, Kang W1, Sun Y1, Emerson R3, Robins H3,4, Levine AJ1,5
Rutgers Cancer Institute of New Jersey, New Brunswick, NJ1; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ2; Biomarker Discovery, Adaptive Biotechnologies, Seattle, WA3; Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA4; Simons Center for Systems Biology, School of Natural Sciences, Institute for Advanced Study, Princeton, NJ5
Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells
Pollack et al.
Journal for ImmunoTherapy of Cancer
Papers
October 2014
Authors and Affiliates
Seth M Pollack, Robin L Jones, Erik A Farrar, Ivy P Lai, Sylvia M Lee, Jianhong Cao, Venu G Pillarisetty, Benjamin L Hoch, Ashley Gullett, Marie Bleakley, Ernest U Conrad, Janet F Eary, Kendall C Shibuya, Edus H Warren, Jason N Carstens, Shelly Heimfeld, Stanley R Riddell and Cassian Yee.
Clinical Research Division, D3-100 Fred Hutchinson Cancer Research Center, 1100 Fairview Ave, Seattle, WA 98109 USA
Department of Medicine, University of Washington, Seattle, WA USA
Department of Surgery, University of Washington, Seattle, WA USA
Department of Pathology, University of Washington, Seattle, WA USA
Department of Pediatrics, University of Washington, Seattle, WA USA
Department of Orthopedics, University of Washington, Seattle, WA USA
Department of Radiology, University of Alabama, Birmingham, AL USA
Institute for Advanced Study, Technical University of Munich, Munich, Germany
Department of Melanoma Medical Oncology, UT
MD Anderson Cancer Center, 7455 Fannin St, Unit 904, Houston, TX 77054 USA
De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4 -related disease
Mattoo et al.
Journal of Allergy and Clinical Immunology
Papers
September 2014
Authors and Affiliates
Mattoo H1, Mahajan VS1, Della-Torre E1, Sekigami Y1, Carruthers M1, Wallace ZS1, Deshpande V1, Stone JH2, Pillai S3.
1Massachusetts General Hospital and Harvard Medical School, Boston, Mass.
2Massachusetts General Hospital and Harvard Medical School, Boston, Mass. Electronic address: jhstone@partners.org.
3Massachusetts General Hospital and Harvard Medical School, Boston, Mass. Electronic address: pillai@helix.mgh.harvard.edu.
Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections
Conti et al.
Journal of Experimental Medicine
Papers
September 2014
Authors and Affiliates
Heather R. Conti,1 Alanna C. Peterson,1 Lucas Brane,1 Anna R. Huppler,5Nydiaris Hernández-Santos,1 Natasha Whibley,1 Abhishek V. Garg,1Michelle R. Simpson-Abelson,1 Gregory A. Gibson,4 Anna J. Mamo,1Lisa C. Osborne,6 Shrinivas Bishu,2 Nico Ghilardi,7 Ulrich Siebenlist,8Simon C. Watkins,4 David Artis,6 Mandy J. McGeachy,1,3 and Sarah L. Gaffen1,3
1Division of Rheumatology and Clinical Immunology, and 2Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, 3Department of Immunology, and 4Center for Biological Imaging, University of Pittsburgh, Pittsburgh, PA 15261, 5Department of Infectious Diseases, Children’s Hospital of Pittsburgh, Pittsburgh, PA 15224, 6Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104. 7Department of Immunology, Genentech Inc., South San Francisco, CA 94080, 8Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852