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Membrane association of the CD3ε signaling domain is required for optimal T cell development and function

Bettini et al.
Journal of Immunology
Papers
July 2014
Authors and Affiliates
Bettini ML1, Guy C1, Dash P1, Vignali KM1, Hamm DE2, Dobbins J3, Gagnon E3, Thomas PG1, Wucherpfennig KW3, Vignali DA4. 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN. 2Adaptive Biotechnologies, Seattle, WA. 3Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA. 4Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.

Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRB repertoire

Lepore et al.
Nature Communications
Papers
May 2014
Authors and Affiliates
Marco Lepore1, Artem Kalinicenko1, Alessia Colone2, Bhairav Paleja2, Amit Singhal2, Andreas Tschumi3, Bernett Lee2, Michael Poidinger2, Francesca Zolezzi2, Luca Quagliata4, Peter Sander3,5, Evan Newell2, Antonio Bertoletti6, Luigi Terracciano4, Gennaro De Libero1,2 & Lucia Mori1,2 1Experimental Immunology, Department of Biomedicine, University Hospital Basel, 4031 Basel, Switzerland. 2 SIgN, Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore. 3Institute of Medical Microbiology, University of Zurich, 8006 Zurich, Switzerland. 4Institute of Pathology, University Hospital Basel, 4031 Basel, Switzerland. 5National Centre for Mycobacteria, Gloriastrasse 30/32, 8006 Zurich, Switzerland. 6Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore 169857, Singapore.

CTLA4 blockade broadens the peripheral T-cell receptor repertoire

Robert et al.
Clinical Cancer Research
Papers
May 2014
Authors and Affiliates
Lidia Robert,1 Jennifer Tsoi,2 Xiaoyan Wang,1,3 Ryan Emerson,7,8 Blanca Homet,1,9 Thinle Chodon,1 Stephen Mok,1,2Rong Rong Huang,4 Alistair J. Cochran,4 Begonya Comin-Anduix,5,6 Richard C. Koya,4,6 Thomas G. Graeber,2,6 Harlan Robins,7,8 and Antoni Ribas1,2,4,6 1Department of Medicine (Division of Hematology-Oncology), University of California Los Angeles (UCLA), 2Department of Molecular and Medical Pharmacology, University of California Los Angeles (UCLA), 3Department of Medicine (Statistics core), University of California Los Angeles (UCLA), 4Department of Pathology and Laboratory Medicine, University of California Los Angeles (UCLA), 5Department of Surgery (Division of Surgical-Oncology), University of California Los Angeles (UCLA), 6Jonsson Comprehensive Cancer Center (JCCC), University of California Los Angeles (UCLA), 7Fred Hutchinson Cancer Research Center, Seattle, WA, 8Adaptive Biotechnologies, Seattle, WA, 9Instituto de Salud Carlos III, Madrid, Spain

Quantifying selection in immune receptor repertoires

Elhanati et al.
Cornell University Library
Papers
April 2014
Authors and Affiliates
Yuval Elhanati,a Anand Murugan,b Curtis G. Callan, Jr.c, Thierry Mora,d and Aleksandra M. Walczaka aLaboratoire de Physique Théorique, Unité Mixte de Recherche 8549, dLaboratoire de Physique Statistique, Unité Mixte de Recherche 8550, Centre National de la Recherche Scientifique and École Normale Supérieure, 75005 Paris, France, bDepartment of Applied Physics, Stanford University, Stanford, CA, 94305; and, cJoseph Henry Laboratories, Princeton University, Princeton, NJ, 08544.

Novel GMP-compatible protocol employing an allogeneic B cell bank for clonal expansion of allospecific natural regulatory T cells

Landwehr-Kenzel et al.
American Journal of Transplantation
Papers
February 2014
Authors and Affiliates
S. Landwehr-Kenzel1,2,3,*, F. Issa4, S.-H. Luu1,2,5, M. Schmück1,6, H. Lei1,2,6, A. Zobel1, A. Thiel1, N. Babel1,5, K. Wood4, H.-D. Volk1,6 and P. Reinke1,5 1Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany, 2Berlin-Brandenburg School for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany, 3Department of Pediatric Pulmonology and Immunology, Charité University Medicine Berlin, Berlin, Germany, 4Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Oxford, United Kingdom, 5Renal and Transplant Research Unit, Department of Nephrology and Internal Intensive Care, Charité University Medicine Berlin, Berlin, Germany, 6Institute of Medical Immunology, Charité University Medicine Berlin, Berlin, Germany.

T cell repertoire following autologous stem cell transplantation for multiple sclerosis

Muraro et al.
JCI
Papers
February 2014
Authors and Affiliates
Paolo A. Muraro,1 Harlan Robins,2 Sachin Malhotra,3 Michael Howell,3 Deborah Phippard,3 Cindy Desmarais,4 Alessandra de Paula Alves Sousa,1 Linda M. Griffith,5 Noha Lim,3 Richard A. Nash,6 and Laurence A. Turka3,7 1Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom. 2Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. 3Immune Tolerance Network, Bethesda, Maryland, USA. 4Adaptive Biotechnologies, Seattle, Washington, USA. 5Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA. 6Colorado Blood Cancer Institute at PSL, Denver, Colorado, USA. 7Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Intramuscular Therapeutic Vaccination Targeting HPV16 Induces T Cell Responses That Localize in Mucosal Lesions

Maldonado et al.
Papers
Science Translational Medicine
January 2014
Authors and Affiliates
Maldonado L1*, Teague JE2*, Morrow MP3*, Jotova I4, Wu TC5, Wang C6, Desmarais C7, Boyer JD8, Tycko B4, Robins HS9, Clark RA2, Trimble CL1,5,10 1 Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. 2 Harvard Skin Disease Research Center and the Department of Dermatology, Brigham and Women's Hospital, Boston, MA 02115, USA. 3 Inovio Pharmaceuticals Inc., 1787 Sentry Parkway West, Building 18, Suite 400, Blue Bell, PA 19422, USA. 4 Department of Pathology and Cell Biology and Institute for Cancer Genetics, Columbia University Medical Center, New York, NY 10025, USA. 5 Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. 6 Oncology Biostatistics, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. 7 Adaptive Biotechnologies, 1551 Eastlake Avenue, Seattle, WA 98102, USA. 8 Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. 9 Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. 10 Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. * Contributed equally
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