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Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections
Conti et al.
Journal of Experimental Medicine
Papers
September 2014
Authors and Affiliates
Heather R. Conti,1 Alanna C. Peterson,1 Lucas Brane,1 Anna R. Huppler,5Nydiaris Hernández-Santos,1 Natasha Whibley,1 Abhishek V. Garg,1Michelle R. Simpson-Abelson,1 Gregory A. Gibson,4 Anna J. Mamo,1Lisa C. Osborne,6 Shrinivas Bishu,2 Nico Ghilardi,7 Ulrich Siebenlist,8Simon C. Watkins,4 David Artis,6 Mandy J. McGeachy,1,3 and Sarah L. Gaffen1,3
1Division of Rheumatology and Clinical Immunology, and 2Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, 3Department of Immunology, and 4Center for Biological Imaging, University of Pittsburgh, Pittsburgh, PA 15261, 5Department of Infectious Diseases, Children’s Hospital of Pittsburgh, Pittsburgh, PA 15224, 6Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104. 7Department of Immunology, Genentech Inc., South San Francisco, CA 94080, 8Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852
High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells
Lossius et al.
European Journal of Immunology
Papers
August 2014
Authors and Affiliates
Lossius A, Johansen JN, Vardal F, Robins H, Saltyte Benth J, Holmoy T, Olweus J.
Membrane association of the CD3ε signaling domain is required for optimal T cell development and function
Bettini et al.
Journal of Immunology
Papers
July 2014
Authors and Affiliates
Bettini ML1, Guy C1, Dash P1, Vignali KM1, Hamm DE2, Dobbins J3, Gagnon E3, Thomas PG1, Wucherpfennig KW3, Vignali DA4.
1Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.
2Adaptive Biotechnologies, Seattle, WA.
3Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA.
4Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.
Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRB repertoire
Lepore et al.
Nature Communications
Papers
May 2014
Authors and Affiliates
Marco Lepore1, Artem Kalinicenko1, Alessia Colone2, Bhairav Paleja2, Amit Singhal2, Andreas Tschumi3, Bernett Lee2, Michael Poidinger2, Francesca Zolezzi2, Luca Quagliata4, Peter Sander3,5, Evan Newell2, Antonio Bertoletti6, Luigi Terracciano4, Gennaro De Libero1,2 & Lucia Mori1,2
1Experimental Immunology, Department of Biomedicine, University Hospital Basel, 4031 Basel, Switzerland. 2 SIgN, Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore. 3Institute of Medical Microbiology, University of Zurich, 8006 Zurich, Switzerland. 4Institute of Pathology, University Hospital Basel, 4031 Basel, Switzerland. 5National Centre for Mycobacteria, Gloriastrasse 30/32, 8006 Zurich, Switzerland. 6Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore 169857, Singapore.
Improved Survival with T Cell Clonotype Stability After Anti–CTLA-4 Treatment in Cancer Patients
Cha et al
Papers
Science Translational Medicine
May 2014
Authors and Affiliates
Edward Cha1, Mark Klinger2, Yafei Hou1, Craig Cummings2, Antoni Ribas3, Malek Faham2 and Lawrence Fong1
1University of California, San Francisco, San Francisco, CA 94143, USA. 2Sequenta, South San Francisco, CA 94080, USA. 3University of California, Los Angeles, Los Angeles, CA 90095, USA.
CTLA4 blockade broadens the peripheral T-cell receptor repertoire
Robert et al.
Clinical Cancer Research
Papers
May 2014
Authors and Affiliates
Lidia Robert,1 Jennifer Tsoi,2 Xiaoyan Wang,1,3 Ryan Emerson,7,8 Blanca Homet,1,9 Thinle Chodon,1 Stephen Mok,1,2Rong Rong Huang,4 Alistair J. Cochran,4 Begonya Comin-Anduix,5,6 Richard C. Koya,4,6 Thomas G. Graeber,2,6 Harlan Robins,7,8 and Antoni Ribas1,2,4,6
1Department of Medicine (Division of Hematology-Oncology), University of California Los Angeles (UCLA), 2Department of Molecular and Medical Pharmacology, University of California Los Angeles (UCLA), 3Department of Medicine (Statistics core), University of California Los Angeles (UCLA), 4Department of Pathology and Laboratory Medicine, University of California Los Angeles (UCLA), 5Department of Surgery (Division of Surgical-Oncology), University of California Los Angeles (UCLA), 6Jonsson Comprehensive Cancer Center (JCCC), University of California Los Angeles (UCLA), 7Fred Hutchinson Cancer Research Center, Seattle, WA, 8Adaptive Biotechnologies, Seattle, WA, 9Instituto de Salud Carlos III, Madrid, Spain
Quantifying selection in immune receptor repertoires
Elhanati et al.
Cornell University Library
Papers
April 2014
Authors and Affiliates
Yuval Elhanati,a Anand Murugan,b Curtis G. Callan, Jr.c, Thierry Mora,d and Aleksandra M. Walczaka
aLaboratoire de Physique Théorique, Unité Mixte de Recherche 8549, dLaboratoire de Physique Statistique, Unité Mixte de Recherche 8550, Centre National de la Recherche Scientifique and École Normale Supérieure, 75005 Paris, France, bDepartment of Applied Physics, Stanford University, Stanford, CA, 94305; and, cJoseph Henry Laboratories, Princeton University, Princeton, NJ, 08544.
Novel GMP-compatible protocol employing an allogeneic B cell bank for clonal expansion of allospecific natural regulatory T cells
Landwehr-Kenzel et al.
American Journal of Transplantation
Papers
February 2014
Authors and Affiliates
S. Landwehr-Kenzel1,2,3,*, F. Issa4, S.-H. Luu1,2,5, M. Schmück1,6, H. Lei1,2,6, A. Zobel1, A. Thiel1, N. Babel1,5, K. Wood4, H.-D. Volk1,6 and P. Reinke1,5
1Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany, 2Berlin-Brandenburg School for Regenerative Therapies, Charité University Medicine Berlin, Berlin, Germany, 3Department of Pediatric Pulmonology and Immunology, Charité University Medicine Berlin, Berlin, Germany, 4Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Oxford, United Kingdom, 5Renal and Transplant Research Unit, Department of Nephrology and Internal Intensive Care, Charité University Medicine Berlin, Berlin, Germany, 6Institute of Medical Immunology, Charité University Medicine Berlin, Berlin, Germany.
T cell repertoire following autologous stem cell transplantation for multiple sclerosis
Muraro et al.
JCI
Papers
February 2014
Authors and Affiliates
Paolo A. Muraro,1 Harlan Robins,2 Sachin Malhotra,3 Michael Howell,3 Deborah Phippard,3 Cindy Desmarais,4 Alessandra de Paula Alves Sousa,1 Linda M. Griffith,5 Noha Lim,3 Richard A. Nash,6 and Laurence A. Turka3,7
1Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom. 2Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. 3Immune Tolerance Network, Bethesda, Maryland, USA. 4Adaptive Biotechnologies, Seattle, Washington, USA. 5Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA. 6Colorado Blood Cancer Institute at PSL, Denver, Colorado, USA. 7Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.