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Vitiligo after alemtuzumab treatment: Secondary autoimmunity is not all about B cells

Ruck et al.
Neurology
December 2018
Authors and Affiliates
Ruck T1, Pfeuffer S2, Schulte-Mecklenbeck A2, Gross CC2, Lindner M2, Metze D2, Ehrchen J2, Sondermann W2, Pul R2, Kleinschnitz C2, Wiendl H2, Meuth SG2, Klotz L2. 1 From the Clinic of Neurology with Institute of Translational Neurology (T.R., S.P., A.S.-M., C.C.G., M.L., H.W., S.G.M., L.K.) and Department of Dermatology (D.M., J.E.), University of Münster; and Departments of Dermatology, Venereology, and Allergology (W.S.) and Neurology (R.P., C.K.), University School of Medicine Essen-Duisburg, Essen, Germany. tobias.ruck@ukmuenster.de. 2 From the Clinic of Neurology with Institute of Translational Neurology (T.R., S.P., A.S.-M., C.C.G., M.L., H.W., S.G.M., L.K.) and Department of Dermatology (D.M., J.E.), University of Münster; and Departments of Dermatology, Venereology, and Allergology (W.S.) and Neurology (R.P., C.K.), University School of Medicine Essen-Duisburg, Essen, Germany.

Tumour associated lymphocytes in the pleural effusions of patients with mesothelioma express high levels of inhibitory receptors

Chee et al.
BMC Research Notes
December 2018
Authors and Affiliates
Chee J1, Watson MW2, Chopra A2, Nguyen B3, Cook AM4, Creaney J4, Lesterhuis WJ4, Robinson BW4,5, Lee YCG5,6, Nowak AK4,3, Lake RA4, McDonnell AM4 1 National Centre for Asbestos Related Diseases, School of Medicine and Pharmacology, University of Western Australia, Nedlands, Western Australia, Australia. jonathan.chee@uwa.edu.au. 2 Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia. 3 Department of Medical Oncology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. 4 National Centre for Asbestos Related Diseases, School of Medicine and Pharmacology, University of Western Australia, Nedlands, Western Australia, Australia. 5 Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. 6 Institute of Respiratory Health, School of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.

Immunological analysis of phase II glioblastoma dendritic cell vaccine (Audencel) trial: immune system characteristics influence outcome and Audencel up-regulates Th1-related immunovariables

Erhart et al.
Acta Neuropathologica
December 2018
Authors and Affiliates
Erhart F1,2, Buchroithner J3, Reitermaier R4, Fischhuber K4, Klingenbrunner S4, Sloma I5, Hibsh D5, Kozol R5, Efroni S5, Ricken G6, Wöhrer A6, Haberler C6, Hainfellner J6, Krumpl G4, Felzmann T4, Dohnal AM7, Marosi C8, Visus C4 1-Institute of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria. friedrich.erhart@meduniwien.ac.at. 2-Department of Neurosurgery, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria. friedrich.erhart@meduniwien.ac.at. 3-University Clinic for Neurosurgery, Kepler University Hospital, Johannes Kepler University, Wagner-Jauregg-Weg 15, 4020, Linz, Austria. 4-Activartis Biotech GmbH, Wilhelminenstraße 91/IIf, 1160, Vienna, Austria. 5-Systems Bio Medicine Lab, Bar Ilan University, 5290002, Ramat Gan, Israel. 6-Institute of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria. 7-Laboratory for Tumor Immunology, CCRI St. Anna Kinderkrebsforschung, Zimmermannplatz 10, 1090, Vienna, Austria. 8-Clinical Division of Medical Oncology, Medical University of Vienna, Währinger Gürtel 18-20, 1097, Vienna, Austria.

Identifying and Tracking Low-Frequency Virus-Specific TCR Clonotypes Using High-Throughput Sequencing

Wolf et al.
Cancer Reports
November 2018
Authors and Affiliates
Wolf K1, Hether T2, Gilchuk P3, Kumar A3, Rajeh A4, Schiebout C4, Maybruck J5, Buller RM1, Ahn TH6, Joyce S3, DiPaolo RJ7. 1 Department of Molecular Microbiology and Immunology, Saint Louis University, Saint Louis, MO 63104, USA. 2 Adaptive Biotechnologies, Seattle, WA 98102, USA. 3 Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN 37212, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA. 4 Program in Bioinformatics and Computational Biology, Saint Louis University, Saint Louis, MO 63104, USA. 5 Federal Bureau of Investigation, Washington, DC 20535, USA. 6 Department of Computer Science, Saint Louis University, Saint Louis, MO 63104, USA; Program in Bioinformatics and Computational Biology, Saint Louis University, Saint Louis, MO 63104, USA. 7 Department of Molecular Microbiology and Immunology, Saint Louis University, Saint Louis, MO 63104, USA. Electronic address: richard.dipaolo@health.slu.edu.

Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma

Blank et al.
Nature Medicine
November 2018
Authors and Affiliates
Blank CU1,2, Rozeman EA3,4, Fanchi LF4, Sikorska K5, van de Wiel B6, Kvistborg P4, Krijgsman O4, van den Braber M4, Philips D4, Broeks A6, van Thienen JV3, Mallo HA3, Adriaansz S3, Ter Meulen S7, Pronk LM5, Grijpink-Ongering LG5, Bruining A8, Gittelman RM9, Warren S10, van Tinteren H5, Peeper DS4, Haanen JBAG3,4, van Akkooi ACJ7, Schumacher TN11. 1 Medical Oncology Department, Netherlands Cancer Institute, Amsterdam, The Netherlands. c.blank@nki.nl. 2 Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands. c.blank@nki.nl. 3 Medical Oncology Department, Netherlands Cancer Institute, Amsterdam, The Netherlands. 4 Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands. 5 Department of Biometrics, Netherlands Cancer Institute, Amsterdam, The Netherlands. 6 Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands. 7 Surgical Oncology Department, Netherlands Cancer Institute, Amsterdam, The Netherlands. 8 Department of Radiology, Netherlands Cancer Institute, Amsterdam, The Netherlands. 9 Adaptive Biotechnologies, Seattle, WA, USA. 10 NanoString Technologies, Inc., Seattle, WA, USA. 11 Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands. t.schumacher@nki.nl.

Microphysiologic Human Tissue Constructs Reproduce Autologous Age-Specific BCG and HBV Primary Immunization in vitro

Sanchez-Schmitz et al.
Frontiers in Immunology
November 2018
Authors and Affiliates
Sanchez-Schmitz G1,2,3, Stevens CR1, Bettencourt IA1, Flynn PJ1, Schmitz-Abe K2,3,4,5, Metser G1, Hamm D6, Jensen KJ7,8,9, Benn C7,8, Levy O1,2,3,5 1 Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, United States. 2 Precision Vaccines Program, Boston Children's Hospital, Boston, MA, United States. 3 Harvard Medical School, Harvard University, Boston, MA, United States. 4 Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, United States. 5 Broad Institute of Harvard and MIT, Cambridge, MA, United States. 6 Adaptive Biotechnologies, Seattle, WA, United States. 7 Research Center for Vitamins and Vaccines, Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark. 8 Bandim Health Project, Indepth Network, Bissau, Guinea-Bissau. 9 Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs Lyngby, Denmark.

Early expansion of donor-specific Tregs in tolerant kidney transplant recipients

Savage et al.
JCI Insight
November 2018
Authors and Affiliates
Savage TM1, Shonts BA1, Obradovic A1, Dewolf S1, Lau S1, Zuber J1, Simpson MT1, Berglund E1, Fu J1, Yang S1, Ho SH1, Tang Q2, Turka LA3,4, Shen Y5, Sykes M1,6,7 1 Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, New York, USA. 2 Department of Surgery, University of California San Francisco, San Francisco, California, USA. 3 Center for Translational Sciences, Department of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA. 4 Immune Tolerance Network, Bethesda, Maryland, USA. 5 Center for Computational Biology and Bioinformatics, Department of Systems Biology, Columbia University, New York, New York, USA. 6 Department of Microbiology & Immunology, Columbia University Medical Center, Columbia University, New York, New York, USA. 7 Department of Surgery, Columbia University Medical Center, Columbia University, New York, New York, USA.

A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus

Chen et al.
Cancer Reports
November 2018
Authors and Affiliates
Chen S1, Luperchio TR2, Wong X2, Doan EB1, Byrd AT1, Roy Choudhury K3, Reddy KL2, Krangel MS4. 1 Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA. 2 Department of Biological Chemistry, Center for Epigenetics, Johns Hopkins University, Baltimore, MD 21205, USA. 3 Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27710, USA. 4 Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: krang001@mc.duke.edu.
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