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Common clonal origin of central and resident memory T cells following skin immunization

Gaide et al.
Nature Medicine
Papers
May 2015
Authors and Affiliates
Gaide O1, Emerson RO2, Jiang X1, Gulati N3, Nizza S1, Desmarais C2, Robins H4, Krueger JG3, Clark RA1, Kupper TS1 1Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. 2Adaptive Biotech, Seattle, Washington, USA. 3Laboratory for Investigative Dermatology, Rockefeller University, New York, New York, USA. 4Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3

Goettel et al.
Blood Journal
Papers
April 2015
Authors and Affiliates
Goettel JA1,2, Biswas S2,3, Lexmond WS1,2, Yeste A2,4, Passerini L5, Patel B2,4, Yang S6, Sun J2,3, Ouahed1,2, Shouval DS1,2, McCann KJ1, Horwitz BH2,7, Mathis D6, Milford EL2,8, Notarangelo LD2,9, Roncarolo MG5,10, Fiebiger E1,2, Marasco WA2,3, Bacchetta R5, Quintana FJ2,4, Pai SY2,11,12, Muise AM13, Snapper SB1,2,14 Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston MA1; Department of Medicine, Harvard Medical School, Boston MA2; Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston MA3; Center for Neurologic Diseases, Brigham and Women's Hospital, Boston MA4; Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, San Raffaele Telethon Institute for Gene Therapy, Milan, Italy5; Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA6; Department of Pathology, Brigham and Women's Hospital, Boston, MA7; Renal Division of Tissue Typing Laboratory, Brigham and Women's Hospital, Boston, MA8; Division of Immunology and the Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA9; Vita-Salute San Raffaele University, Milan, Italy10; Division of Hematology-Oncology, Boston Children's Hospital, Boston, MA11; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA12; Division of Gastroenterology, Hepatology, and Nutrition, Department of Paediatrics, Hospital for Sick Children, Toronto, CA13; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA14

A dendritic cell vaccine increases the breadth of diversity of melanoma neoantigen-specific T cells

Carreno et al.
Papers
ScienceXpress
April 2015
Authors and Affiliates
Carreno BM1, Magrini V2, Becker-Hapak M1, Kaabinejadian S3, Hundal J2, Petti AA2, Ly A2, Lie WR4, Hildebrand WH3, Mardis ER2, Linette GP1 Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO1; Genome Institute, Washington University School of Medicine, St. Louis MO2; Department of Microbiology and Immunology, University of Oklahoma Health Science Center, Oklahoma City, OK3; EMD Millipore Corporation, Billerica, MA4

CMV reactivation drives post-transplant T cell reconstitution and results in defects in the underlying TCRβ repertoire

Suessmuth et al.
Blood Journal
Papers
April 2015
Authors and Affiliates
Suessmuth Y1, Mukherjee R2, Watkins B3, Koura DT4, Finstermeier K5, Desmarais C5, Stempora L1, Horan JT3, Langston A4, Qayed M3, Khoury HJ4, Grizzle A3, Chessman JA1, Conger JA1, Robertson J1, Garrett A3, Kirk AD1, Waller EK4, Blazar BR6, Mehta AK1, Robins HS2, Kean LS7 1The Emory Transplant Center, Emory University School of medicine, Atlanta, GA; 2Fred Hutchinson Cancer Research Center, Seattle, WA; 3Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA; 4Winship Cancer Institute of Emory University, Atlanta, GA; 5Adaptive Biotechnologies Corp, Seattle, WA; 6Department of Pediatrics, Division of Blood and Morrow Transplantation, University of Minnesota School of Medicine, Minneapolis, MN; 7Ben Towne Center for Childhood Cancer Research, Seattle, WA

Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis

Salou et al
Annals of Clinical and Translational Neurology
Papers
April 2015
Authors and Affiliates
Salou M1, Garcia A2, Michel L3, Gainche-Salmon A4, Loussouarn D5, Nicol B1, Guillot F1, Hulin P6, Nedellec S6, Baron D7, Ramstein G8, Soulillou JP4, Brouard S2, Nicot AB7, Degauque N2, Laplaud DA9.

Changes in peanut-specific T-cell clonotype with oral immunotherapy

Bégin et al.
Papers
The Journal of Allergy and Clinical Immunology
April 2015
Authors and Affiliates
Bégin, P1, Nadeau, KC2. 1Department of Pediatrics, Sainte-Justine Hospital, Montreal, Quebec, Canada; Department of Medicine, University of Montreal Health Center, Montreal, Quebec, Canada. 2Division of Allergy, Immunology and Rheumatology, Sean N. Parker Center for Allergy Research at Stanford University, Stanford University School of Medicine, Stanford, Calif