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Polyclonal, newly derived T cells with low expression of inhibitory molecule PD-1 in tonsils define the phenotype of lymphocytes in children with Periodic Fever, Aphtous Stomatitis, Pharyngitis and Adenitis (PFAPA) syndrome

Dytrych et al.
Molecular Immunology
Papers
January 2015
Authors and Affiliates
Dytrych P1, Krol P2, Kotrova M3, Kuzilkova D3, Hubacek P3,4, Krol L3, Katra R1, Hrusak O3, Kabelka Z1, Dolezalova P2, Kalina T3, Fronkova E3 Department of ENT, Charles University, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Czech Republic1; Pediatric Rheumatology Unit, Department of Pediatrics and Adolescent Medicine, Charles University Prague and General University Hospital in Prague, 1st Faculty of Medicine, Czech Republic2; CLIP, Department of Paediatric Haematology/Oncology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol Czech Republic3; Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Czech Republic4

The Analysis Of Clonal Diversity And Therapy Responses Using STAT3 Mutations As A Molecular Marker In Large Granular Lymphocytic Leukemia

Rajala et al.
Haematologica
Papers
January 2015
Authors and Affiliates
Rajala HL1, Olson T2, Clemente MJ3, Lagström S4, Ellonen P4, Lundan T5, Hamm DE6, Zaman SA4, Lopez Marti JM4,Andersson EI1, Jerez A7, Porkka K1, Maciejewski JP3, Loughran TP2, Mustjoki S8. 1Hematology Research Unit, Department of Hematology, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland. 2University of Virginia Cancer Center, Charlottesville, VA, USA. 3Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA. 4Institute for Molecular Medicine (FIMM), University of Helsinki, Finland. 5Department of Clinical Chemistry and TYKSLAB, University of Turku and Turku University Central Hospital, Finland. 6Adaptive Biotechnologies Corp, Seattle, WA, USA. 7Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA Hematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, Universidad de Murcia, IMIB-Arrixaca, Murcia, Spain. 8Hematology Research Unit, Department of Hematology, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland

A Circulating Reservoir of Pathogenic-Like CD4+ T Cells Shares a Genetic and Phenotypic Signature with the Inflamed Synovial Micro-Environment

Spreafico et al.
Ann Rheum Dis
Papers
December 2014
Authors and Affiliates
Spreafico R1,2, Rossetti M1,2, van Loosdregt J1, Wallace CA3, Massa M4, Magni-Manzoni S5, Gattorno M6, Martini A6, Lovell DJ7,8, Albani S1,2 Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, CA1; Singhealth Translational Immuology and Inflammation Centre, Singhealth and Duke-NUS Graduate Medical School, Singapore, Singapore2; Seattle Children's Hospital and Research Institute, Seattle, WA3; Lab Biotecnologie, Fondazione IRCCS Piloclinico San Matteo, Pavia, Italy4; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesu, Rome, Italy5; Second Pediatrics Division, University of Genoa and G Gaslini Institute, Genova, Italy6; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH7; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH8

Emergence of a STAT3 Mutated NK Clone in LGL Leukemia

Yan et al.
Leukemia Research Reports
Papers
December 2014
Authors and Affiliates
Yan Y1, Olson TL2, Nyland SB2, Feith DJ2, Loughran Jr TP2 Department of Medicine, York Hospital, York, PA1; University of Virginia Cancer Center, Charlottesville, VA2

Functional Heterogeneity of Human Memory CD4+ T Cell Clones Primed By Pathogens or Vaccines

Becattini et al.
Papers
ScienceXpress
December 2014
Authors and Affiliates
Becattini S1,2, Latorre D1, Mele F1, Foglierini M1, De Gregorio C1, Cassotta A1, Fernandez B1, Kelderman S3, Schumacher TN3, Corti D1, Lanzavecchia A1,2, Sallusto F1 Institute for Research in Biomedicine, Universita della Svizzera Italiana, Bellinzona, Switzerland1; Institute of Microbiology, ETH Zurich, Zurich, Switzerland2; Division of Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands3

Immune activation and a 9-year ongoing complete remission following CD40 antibody therapy and metastasectomy in a patient with metastatic melanoma

Bajor et al.
Cancer Immunology Research
Papers
November 2014
Authors and Affiliates
Bajor DL1, Xu X2, Torigian DA3, Mick R4, Garcia LR5, Richman LP5, Desmarais C6, Nathanson KL7, Schuchter LM1, Kalos M2, Vonderheide RH8 1Abramson Cancer Center, University of Pennsylvania, Philadelphia. Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia. Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 2Abramson Cancer Center, University of Pennsylvania, Philadelphia. Department of Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 3Abramson Cancer Center, University of Pennsylvania, Philadelphia. Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 4Abramson Cancer Center, University of Pennsylvania, Philadelphia. Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 5Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, 6Adaptive Biotechnologies, Seattle, Washington, 7Abramson Cancer Center, University of Pennsylvania, Philadelphia. Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 8Abramson Cancer Center, University of Pennsylvania, Philadelphia. Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia. Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia. rhv@exchange.upenn.edu.
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