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CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

Turtle et al.
Papers
The Journal of Clinical Investigation
April 2016
Authors and Affiliates
Cameron J. Turtle,1,2 Laïla-Aïcha Hanafi,1 Carolina Berger,1,2 Theodore A. Gooley,1 Sindhu Cherian,3 Michael Hudecek,1 Daniel Sommermeyer,1Katherine Melville,1 Barbara Pender,1 Tanya M. Budiarto,1 Emily Robinson,1 Natalia N. Steevens,1 Colette Chaney,1 Lorinda Soma,3 Xueyan Chen,3 Cecilia Yeung,3,4 Brent Wood,3,4 Daniel Li,5 Jianhong Cao,1 Shelly Heimfeld,1 Michael C. Jensen,1,6 Stanley R. Riddell,1,2,7 and David G. Maloney1,2 1 Clinical Research Division, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, Washington, USA. 2 Department of Medicine, 3 Department of Laboratory Medicine, and 4 Department of Pathology, University of Washington, Seattle, Washington, USA. 5 Juno Therapeutics, Seattle, Washington, USA. 6 Seattle Children’s Research Institute, Seattle, Washington, USA. 7 Institute for Advanced Study, Technical University of Munich, Munich, Germany

Immune DNA signature of T-cell infiltration in breast tumor exomes

Levy et al.
bioRxiv
Papers
April 2016
Authors and Affiliates
Eric Levy,1,2 Rachel Marty,2,3 Valentina Garate-Calderon,4,5 Brian Woo,6 Michelle Dow,1,2 Ricardo Armisen,4,5 Hannah Carter,3,6,7 Olivier Harismendy,1,6 1Division of Biomedical Informatics, Department of Medicine, University of California San Diego 2Bioinformatics and Systems Biology Graduate Program, University of California San Diego 3Division of Medical Genetics, Department of Medicine, University of California San Diego 4Centro de Investigación y Tratamiento del Cancer, Facultad de Medicina, Universidad de Chile 5Center for Excellence in Precision Medicine, Pfizer Chile 6Moores Cancer Center, University of California San Diego 7Institute for Genomic Medicine, University of California San Diego.

Rapid Evolution of the CD8+ TCR Repertoire in Neonatal Mice

Carey et al.
Journal of Immunology
Papers
March 2016
Authors and Affiliates
Alison J. Carey*,†, Donald T. Gracias†,1, Jillian L. Thayer†, Alina C. Boesteanu†,2,Ogan K. Kumova†, Yvonne M. Mueller†,‡, Jennifer L. Hope†,‡, Joseph A. Fraietta§,David B. H. van Zessen‡,¶ and Peter D. Katsikis†,‡ *Pediatrics, Drexel University College of Medicine, Philadelphia, PA 19102; †Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19102; ‡Immunology, Erasmus University Medical Center, 015 N Rotterdam, the Netherlands; §Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA 19104; and ¶Bioinformatics, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands

TCR Sequencing Can Identify and Track Glioma-Infiltrating T Cells after DC Vaccination

Hsu et al.
Cancer Immunology Research
Papers
March 2016
Authors and Affiliates
Melody S. Hsu1,2, Shaina Sedighim1, Tina Wang1,3, Joseph P. Antonios1,4, Richard G. Everson1, Alexander M. Tucker1, Lin Du5, Ryan Emerson6, Erik Yusko6, Catherine Sanders6, Harlan S. Robins6,7, William H. Yong8,9, Tom B. Davidson1,2,8, Gang Li5,8, Linda M. Liau1,8, and Robert M. Prins1,8,10, 1Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California. 2Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, California. 3Department of Medicine (Hematology/Oncology), David Geffen School of Medicine at UCLA, Los Angeles, California. 4Medical Scientist Training Program, David Geffen School of Medicine at UCLA, Los Angeles, California. 5Department of Biostatistics, David Geffen School of Medicine at UCLA, Los Angeles, California. 6Adaptive Biotechnologies, Seattle, Washington. 7Fred Hutchinson Cancer Research Center, Seattle, Washington. 8Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, California. 9Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California. 10Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California.

Inclusion of Strep-tag II in design of antigen receptors for T-cell immunotherapy

Liu et al.
Nature Biotechnology
Papers
February 2016
Authors and Affiliates
Lingfeng Liu1, Daniel Sommermeyer1, Alexandra Cabanov1, Paula Kosasih1, Tyler Hill1 & Stanley R Riddell1–3 1Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. 2Department of Medicine, University of Washington, Seattle, Washington, USA. 3Institute for Advanced Study, Technical University of Munich, Munich, Germany

On the organization of human T-cell receptor loci: log-periodic distribution of T-cell receptor gene segments

Toor
Papers
The Royal Society Interface
January 2016
Authors and Affiliates
Toor AA1, Toor AA2, Rahmani M3, Manjili MH4 1Bone Marrow Transplant Program, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA 2School of Engineering, Virginia Commonwealth University, Richmond, VA, USA. 3Hematology and Oncology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, USA. 4Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA, USA.
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