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Short-term assessment of BCR repertoires of SLE patients after high dose glucocorticoid therapy with high-throughput sequencing

Shi et al.
Papers
January 2016
Authors and Affiliates
Bin Shi,1 Jiang Yu,2 Long Ma,3 Qingqing Ma,4 Chunmei Liu,5 Suhong Sun,6 Rui Ma,3 Xinsheng Yao3 1Department of Laboratory Medicine, Zunyi Medical University, Zunyi, 563000 China. 2Cell Engineering Laboratory, The First Affiliated Hospital of ZunYi Medical University, Zunyi, China. 3Department of Immunology, Research Center for Medicine and Biology, Innovation and Practice Base for Graduate Students Education, Zunyi Medical University, Zunyi, 563000 China. 4Central Laboratory, Guizhou Aerospace Hospital, Zunyi, China. 5Department of Nephropathy and Rheumatology, The First Affiliated Hospital of ZunYi Medical University, Zunyi, China. 6Department of Breast Surgery, The First Affiliated Hospital of ZunYi Medical University, Zunyi, China.

Extensive CD4 and CD8 T Cell Cross-Reactivity between Alphaherpesviruses

Jing et al.
Journal of Hepatology
Papers
January 2016
Authors and Affiliates
Jing L#1, Laing KJ#1, Dong L1, Russell RM1, Barlow RS2, Haas JG3,4, Ramchandani MS1, Johnston C1, Buus S5, Redwood AJ6, White KD7, Mallal SA6,7, Phillips EJ6,7, Posavad CM8,9, Wald A1,10,8,9, Koelle DM1,2,8,9,11. 1 Department of Medicine, University of Washington, Seattle, USA. 2 Department of Global Health, University of Washington, Seattle, USA. 3 Max von Pettenkofer-Institute, Munich, Germany. 4 Division of Pathway Medicine, University of Edinburgh, United Kingdom. 5 Laboratory of Experimental Immunology, University of Copenhagen, Copenhagen, Denmark. 6 Institute for Immunology and Infectious Diseases, Murdoch University, Perth, WA, Australia. 7 Department of Medicine, Vanderbilt University School of Medicine, Nashville, USA. 8 Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, USA. 9 Department of Laboratory Medicine, University of Washington, Seattle, USA. 10 Department of Epidemiology, University of Washington, Seattle, USA. 11 Benaroya Research Institute, Seattle, USA. # Contributed equally.

Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

Gros et al.
Nature Medicine
Papers
January 2016
Authors and Affiliates
Alena Gros, Maria R Parkhurst, Eric Tran, Anna Pasetto, Paul F Robbins, Sadia Ilyas, Todd D Prickett, Jared J Gartner, Jessica S Crystal, Ilana M Roberts, Kasia Trebska-McGowan, John R Wunderlich, James C Yang & Steven A Rosenberg. Surgery Branch, National Cancer Institute (NCI), National Institutes of Health, Bethesda, Maryland, USA.

High-throughput sequencing of immune repertoires in multiple sclerosis

Lossius et al.
Annals of Clinical and Translational Neurology
January 2016
Authors and Affiliates
Andreas Lossius1,2,3, Jorunn N. Johansen1, Frode Vartdal1,3 & Trygve Holmøy3,4 1Department of Immunology and Transfusion Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway 2Department of Neurology, Oslo University Hospital Rikshospitalet, Oslo, Norway 3Institute of Clinical Medicine, University of Oslo, Oslo, Norway 4Department of Neurology, Akershus University Hospital, Lørenskog, Norway

Next Generation Sequencing Reveals Restriction and Clonotypic Expansion of Regulatory T Cells in Juvenile Idiopathic Arthritis

Henderson et al.
Arthritis & Rheumatology
Papers
January 2016
Authors and Affiliates
Lauren A. Henderson, MD, MMSc1 ; Stefano Volpi, MD1 ; Francesco Frugoni, MS1 ; Erin Janssen, MD, PhD1 ; Susan Kim, MD, MMSc1 ; Robert P. Sundel, MD1 ; Fatma Dedeoglu, MD1 ; Mindy S. Lo, MD, PhD1 ; Melissa M. Hazen, MD1 ; Mary Beth Son, MD1 ; Ronald Mathieu, MStox, MPHD2 ; David Zurakowski, PhD3 ; Neng Yu, MD4 ; Tatiana Lebedeva, PhD4 ; Robert C. Fuhlbrigge, MD, PhD1,5; Jolan E. Walter, MD, PhD1,6; Yu Nee Lee, PhD1 ; Peter A. Nigrovic, MD1,7; Luigi D. Notarangelo, MD1,8 1Division of Immunology, Boston Children’s Hospital, Boston, MA 2Division of Hematology and Oncology, Boston Children’s Hospital, Boston, MA 3Department of Anesthesia, Boston Children’s Hospital, Boston, MA 4American Red Cross Blood Services-East Division, New England HLA Services, Dedham, MA 5Department of Dermatology, Brigham and Women’s Hospital, Boston, MA 6Division of Pediatric Allergy/Immunology, Massachusetts General Hospital for Children, Boston, MA, USA 7Division of Rheumatology, Immunology, and Allergy, Brigham and Women’s Hospital, Boston, MA 8Harvard Stem Cell Institute, Boston, MA

IL-25/IL-33–responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa

Lam et al.
Papers
The Journal of Allergy and Clinical Immunology
December 2015
Authors and Affiliates
Emily P. S. Lam, PhD,1,8 Harsha H. Kariyawasam, FRCP, PhD,2,8 Batika M. J. Rana, PhD,3,8 Stephen R. Durham, MD, FRCP,4,8 Andrew N. J. McKenzie, PhD,3 Nicholas Powell, MRCP, PhD,5 Nara Orban, MD,4 Melissa Lennartz-Walker, MSc,1,8 Claire Hopkins, FRCS (ORL-HNS),7 Sun Ying, MD, PhD,1 Joanne Rimmer, FRCS (ORL-HNS),2 Valerie J. Lund, MD, FRCS,2 David J. Cousins, PhD,5,8 and Stephen J. Till, FRCP, PhD1,8 1The Division of Asthma, Allergy and Lung Biology, Guy’s Hospital, King’s College London; 2the Allergy and Medical Rhinology Section, Royal National Throat Nose Ear Hospital, University College London; 3the Medical Research Council Laboratory of Molecular Biology, Cambridge; 4the Section of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London; 5the Division of Transplantation Immunology and Mucosal Biology and Medical Research Council Centre for Transplantation, King’s College London; 6the Department of Infection, Immunity and Inflammation, NIHR Leicester Respiratory Biomedical Research Unit, Leicester Institute for Lung Health, University of Leicester; 7the Department of ENT, Guy’s and St Thomas’ Hospital, London; and 8the Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, London.

The Evolution of Tumors in Mice and Humans with Germline p53 Mutations

Levine, AJ
Cold Spring Harbor Symposia on Quantitative Biology
December 2015
Authors and Affiliates
Levine AJ1, Chan CS2, Dudgeon C3, Puzio-Kuter A3, Hainaut P4. 1Institute for Advanced Study, Princeton, New Jersey 08540 Cancer Institute of New Jersey, New Brunswick, New Jersey 08903 2Cancer Institute of New Jersey, New Brunswick, New Jersey 08903 Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Jersey 08903. 3Cancer Institute of New Jersey, New Brunswick, New Jersey 08903. 4Grenoble Institute for Research on Cancer, Grenoble 38706, France.

Targeting of HPV-16+ Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6

Lindsey M. Draper
Clinical Cancer Research
Papers
December 2015
Authors and Affiliates
Lindsey M. Draper1, Mei Li M. Kwong1, Alena Gros1, Sanja Stevanovic1, Eric Tran1, Sid Kerkar2, Mark Raffeld2, Steven A. Rosenberg1, and Christian S. Hinrichs1 1 Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. 2 Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland

Immunogenicity of somatic mutations in human gastrointestinal cancers.

Tran et al.
Papers
Science
December 2015
Authors and Affiliates
Tran E1, Ahmadzadeh M1, Lu YC1, Gros A1, Turcotte S1, Robbins PF1, Gartner JJ1, Zheng Z1, Li YF1, Ray S1, Wunderlich JR1, Somerville RP1, Rosenberg SA2. 1Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. 2Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Bi-Allelic TCRα or β Recombination Enhances T Cell Development but Is Dispensable for Antigen Responses and Experimental Autoimmune Encephalomyelitis

Shuldt et al.
Papers
PLOS ONE
December 2015
Authors and Affiliates
Nathaniel J. Schuldt1,3, Jennifer L. Auger1,3, Kristin A. Hogquist1,2,3, Bryce A. Binstadt1,3 1Departments of Pediatrics, University of Minnesota, Minneapolis, United States of America, 2Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, United States of America, 3Center for Immunology, University of Minnesota, Minneapolis, United States of America
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