A high density of tertiary lymphoid structure B cells in lung tumors is associated with increased CD4+ T cell receptor repertoire clonality

Zhu W1, Germain C2, Liu Z1, Sebastian Y1, Devi P2, Knockaert S2, Brohawn P1, Lehmann K1, Damotte D3, Validire P4, Yao Y1, Valge-Archer V5, Hammond SA6, Dieu-Nosjean MC2, Higgs BW1 1Translational Sciences; MedImmune ; Gaithersburg, MD USA. 2Laboratory "Cancer, Immune Control, and Escape"; INSERM UMRS 1138; Cordeliers Research Center ; Paris, France ; University Sorbonne; University Pierre and Marie Curie; UMRS 1138 ; Paris, France ; University Sorbonne Paris Cité; University Paris Descartes; UMRS 1138 ; Paris, France. 3Laboratory "Cancer, Immune Control, and Escape"; INSERM UMRS 1138; Cordeliers Research Center ; Paris, France ; University Sorbonne; University Pierre and Marie Curie; UMRS 1138 ; Paris, France ; University Sorbonne Paris Cité; University Paris Descartes; UMRS 1138 ; Paris, France ; Department of Pathology; Cochin Hospital; AP-HP ; Paris, France. 4Laboratory "Cancer, Immune Control, and Escape"; INSERM UMRS 1138; Cordeliers Research Center ; Paris, France ; University Sorbonne; University Pierre and Marie Curie; UMRS 1138 ; Paris, France ; University Sorbonne Paris Cité; University Paris Descartes; UMRS 1138 ; Paris, France ; Department of Pathology; Institut Mutualiste Montsouris ; Paris, France. 5Oncology Research; MedImmune ; Cambridge, UK. 6Oncology Research; MedImmune ; Gaithersburg, MD USA. Abstract Reference