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Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer

Berner et al.
JAMA Oncology
July 2019
Authors and Affiliates
Fiamma Berner 1, David Bomze 2, Stefan Diem 2 3 4, Omar Hasan Ali 2 3 5 6, Mirjam Fässler 2 6, Sandra Ring 1 2, Rebekka Niederer 2 6, Christoph J Ackermann 3, Petra Baumgaertner 7, Natalia Pikor 2, Cristina Gil Cruz 2, Willem van de Veen 8 9, Mübeccel Akdis 8, Sergey Nikolaev 10 11, Heinz Läubli 12 13, Alfred Zippelius 12 13, Fabienne Hartmann 2, Hung-Wei Cheng 2, Gideon Hönger 14 15 16, Mike Recher 17, Jonathan Goldman 18, Antonio Cozzio 6, Martin Früh 3 19, Jacques Neefjes 20, Christoph Driessen 2 3, Burkhard Ludewig 2, Ahmed N Hegazy 21 22, Wolfram Jochum 23, Daniel E Speiser 7, Lukas Flatz 2 3 5 6; 1Microbiology and Immunology PhD Program, University of Zurich, Zurich, Switzerland. 2Institute of Immunobiology, Kantonsspital St Gallen, St Gallen, Switzerland. 3Department of Oncology and Haematology, Kantonsspital St Gallen, St Gallen, Switzerland. 4Department of Oncology and Haematology, Spital Grabs, Grabs, Switzerland. 5Department of Dermatology, University Hospital Zurich, Zurich, Switzerland. 6Department of Dermatology and Allergology, Kantonsspital St Gallen, St Gallen, Switzerland. 7Department of Oncology, Ludwig Cancer Research, University of Lausanne, Lausanne, Switzerland. 8Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland. 9Christine Kühne - Center for Allergy Research and Education, Davos, Switzerland. 10Gustave Roussy Cancer Campus, Villejuif, France. 11University Paris 7, St Louis Hospital, Paris, France. 12Cancer Immunology Laboratory, Department of Biomedicine, University Hospital Basel, Basel, Switzerland. 13Division of Oncology, Department of Internal Medicine, University Hospital Basel, Basel, Switzerland. 14Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland. 15HLA-Diagnostics and Immunogenetics, Department of Laboratory Medicine, University Hospital Basel, Basel, Switzerland. 16Transplantation Immunology and Nephrology, Department of Biomedicine, University Basel, Basel, Switzerland. 17Immunodeficiency Clinic and Immunodeficiency Lab, Medical Outpatient Unit and Department Biomedicine, University Hospital Basel, Basel, Switzerland. 18David Geffen School of Medicine, Department of Medicine, UCLA (University of California, Los Angeles), Ronald Reagan UCLA Medical Center, Santa Monica. 19University of Bern, Bern, Switzerland. 20Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands. 21Medical Department for Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, Berlin, Germany. 22Berlin Institute of Health, Berlin, Germany. 23Institute of Pathology, Kantonsspital St Gallen, St Gallen, Switzerland.