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Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation

Bigley et al.
Journal of Allergy and Clinical Immunology
Papers
November 2017
Authors and Affiliates
Venetia Bigley, MD, PhD,a,b Sheetal Maisuria, MSc,c Urszula Cytlak, PhD,a Laura Jardine, MD,a,b Matthew A. Care, PhD,d Kile Green, MSc,a Merry Gunawan, PhD,a Paul Milne, PhD,a Rachel Dickinson, PhD,a Sarah Wiscombe, MD,a David Parry, PhD,e Rainer Doffinger, MD, PhD,f Arian Laurence, MD, PhD,a,b Claudia Fonseca, Lic,g Oda Stoevesandt, PhD,g Andrew Gennery, MD, PhD,a,b Andrew Cant, MD, PhD,b Reuben Tooze, MD, PhD,d A. John Simpson, MD, PhD,a,b Sophie Hambleton, MD, PhD,a,b Sinisa Savic, MD, PhD,h Gina Doody, PhD,d and Matthew Collin, MD, PhDa,b aThe Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne; bNewcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne; cLeeds Institute of Rheumatic and Musculoskeletal Medicine, dLeeds Institute of Cancer and Pathology, eLeeds Institute of Biomedical and Clinical Sciences, and hthe National Institute for Health Research–Leeds Musculoskeletal Biomedical Research Unit and Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; fthe Department of Clinical Biochemistry and Immunology, Addenbrookes Hospital, Cambridge; and gCambridge Protein Arrays, Babraham Research Campus, Cambridge.