Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease

Thapa M1, Tedesco D2, Gumber S3, Elrod EJ2, Han JH2, Kitchens WH4, Magliocca JF4, Adams AB4, Grakoui A1,5.; 1 Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329; manoj.thapa@emory.edu arash.grakoui@emory.edu. 2 Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30329. 3 Division of Pathology and Laboratory Medicine, Yerkes Research Primate Center, Emory University School of Medicine, Atlanta, GA 30329. 4 Division of Transplantation, Department of Surgery, Emory University School of Medicine, Atlanta, GA 30329; and. 5 Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30329.