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Deep Sequencing of T-Cell Receptor DNA as a biomarker of clonally expanded TILs in breast cancer after immunotherapy

Page et al.
Cancer Immunology Research
Papers
September 2016
Authors and Affiliates
David B. Page1,2, Jianda Yuan1, David Redmond3, Y Hanna Wen1, Jeremy C. Durack1, Ryan Emerson4, Stephen Solomon1, Zhiwan Dong1, Phillip Wong1, Christopher Comstock1, Adi Diab5, Janice Sung1, Majid Maybody1, Elizabeth Morris1, Edi Brogi1, Monica Morrow1, Virgilio Sacchini1, Olivier Elemento3, Harlan Robins6, Sujata Patil1, James P. Allison5, Jedd D. Wolchok1,3, Clifford Hudis1,3, Larry Norton1,3, and Heather McArthur1,3 1Medical Oncology, Providence Portland Medical Center / Robert W. Franz Cancer Research Center and Earl A. Chiles Research Institute; 2Memorial Sloan-Kettering Cancer Center; 3Weill Cornell Medical College 4Adaptive Biotechnologies; 5Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center; 6Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medical College; 7Human Biology Division, Fred Hutchinson Cancer Research Center; 8Immunology, University of Texas MD Anderson Cancer Center; 9Ludwig Center for Cancer Immunotherapy, Memorial Sloan-Kettering Cancer Center; 10Medicine, Breast Medicine Service, Memorial Sloan-Kettering Cancer Center