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Exhaustion of tumour-infiltrating T-cell receptor repertoirediversity is an age-dependent indicator of immunological fit-ness independently predictive of clinical outcome in Burkittlymphoma

Rieken J., et al.
British Journal of Haematology
September 2020
Authors and Affiliates
Johannes Rieken 1, Veronica Bernard 2, Hanno M Witte 1,3, Wolfgang Peter 4, Hartmut Merz 2, Vito Olschewski 1, Lars Hertel 5, Hendrik Lehnert 6, Harald Biersack 1, Nikolas von Bubnoff 1, Alfred C Feller 2, Niklas Gebauer 1; 1 Department of Haematology and Oncology, University Hospital of Schleswig-Holstein, Luebeck, Germany. 2 Hämatopathologie Lübeck, Reference Centre for Lymph Node Pathology and Haematopathology, Lübeck, Germany. 3 Department of Haematology and Oncology, Federal Armed Hospital Ulm, Ulm, Germany. 4 HLA Typing Laboratory of the Stefan-Morsch-Foundation, Birkenfeld, Germany. 5 Department of Neuro- and Bioinformatics, University Hospital of Schleswig-Holstein, Luebeck, Germany. 6 Department of Internal Medicine I, University Hospital of Schleswig-Holstein, Luebeck, Germany.