Expansion of the CD4 + effector T-cell repertoire characterizes peanut-allergic patients with heightened clinical sensitivity

Bert Ruiter 1, Neal P Smith 2, Brinda Monian 3, Ang A Tu 3, Elizabeth Fleming 2, Yamini V Virkud 4, Sarita U Patil 4, Charles A Whittaker 5, J Christopher Love 3, Wayne G Shreffler 4; 1 Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address: bruiter@mgh.harvard.edu. 2 Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Boston, Mass. 3 Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Mass. 4 Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, Boston, Mass; Harvard Medical School, Boston, Mass; Food Allergy Center, Massachusetts General Hospital, Boston, Mass. 5 Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Mass; The Barbara K. Ostrom (1978) Bioinformatics and Computing Facility in the Swanson Biotechnology Center, Massachusetts Institute of Technology, Cambridge, Mass.