Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis

Kristina M. Harris1, Noha Lim1, Paul Lindau2, Harlan Robins2,3, Linda M. Griffith4, Richard A. Nash5, Laurence A. Turka1,6, and Paolo A. Muraro7 1Immune Tolerance Network (ITN), Bethesda, Maryland, USA 2Fred Hutchinson Cancer Research Center, Seattle, Washington, USA 3Adaptive Biotechnologies, Seattle, Washington, USA 4 Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA 5Colorado Blood Cancer Institute at Presbyterian / St. Luke’s, Denver, Colorado, USA 6Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA 7Department of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom