Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy

Chai Fen Soon 1,2, Shihong Zhang 1, Pothakamuri Venkata Suneetha 1, Dinler Amaral Antunes 3, Michael Peter Manns 1,2, Solaiman Raha 4, Christian Schultze-Florey 4,5, Immo Prinz 2,4, Heiner Wedemeyer 1,6,7, Margaret Sällberg Chen 8,9, Markus Cornberg 1,2,6,10,11; 1 Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hanover, Germany. 2 Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hanover, Germany. 3 Department of Computer Science, Rice University, Houston, TX, United States. 4 Hannover Medical School, Institute of Immunology, Hanover, Germany. 5 Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hanover, Germany. 6 German Center for Infection Research, Partner Site Hannover-Braunschweig, Hanover, Germany. 7 Department of Gastroenterology and Hepatology, University Clinic Essen, Essen, Germany. 8 Department of Dental Medicine and Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden. 9 Shanghai Tenth People's Hospital, Tongji University, Shanghai, China. 10 Centre for Individualised Infection Medicine, Hanover, Germany. 11 Helmholtz Centre for Infection Research, Braunschweig, Germany.