Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate

Akhilesh Pandey 1,2,3, Eric W Stawiski 4,5,6, Steffen Durinck 7,8, Harsha Gowda 9,10, Leonard D Goldstein 7,8, Mustafa A Barbhuiya 9,11, Markus S Schröder 8,12, Sreelakshmi K Sreenivasamurthy 9, Sun-Whe Kim 13, Sameer Phalke 14, Kushal Suryamohan 15, Kayla Lee 15, Papia Chakraborty 15, Vasumathi Kode 15, Xiaoshan Shi 15, Aditi Chatterjee 9, Keshava Datta 9, Aafaque A Khan 9, Tejaswini Subbannayya 9, Jing Wang 15, Subhra Chaudhuri 8, Sanjiv Gupta 16, Braj Raj Shrivastav 17, Bijay S Jaiswal 8, Satish S Poojary 18, Shushruta Bhunia 18, Patricia Garcia 19, Carolina Bizama 19, Lorena Rosa 20, Wooil Kwon 13, Hongbeom Kim 13, Youngmin Han 13, Thakur Deen Yadav 21, Vedam L Ramprasad 14, Amitabha Chaudhuri 15, Zora Modrusan 8, Juan Carlos Roa 19, Pramod Kumar Tiwari 18, Jin-Young Jang 22, Somasekar Seshagiri 23,24; 1 Institute of Bioinformatics, Bangalore, Karnataka, 560066, India. pandey.akhilesh@mayo.edu. 2 Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, 576104, India. pandey.akhilesh@mayo.edu. 3 Center for Individualized Medicine and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA. pandey.akhilesh@mayo.edu. 4 Bioinformatics and Computational Biology Department, Genentech Inc, South San Francisco, CA, 94080, USA. eric.s@medgenome.com. 5 Molecular Biology Department, Genentech Inc., South San Francisco, CA, 94080, USA. eric.s@medgenome.com. 6 Research and Development Department, MedGenome Inc, Foster City, CA, 94404, USA. eric.s@medgenome.com. 7 Bioinformatics and Computational Biology Department, Genentech Inc, South San Francisco, CA, 94080, USA. 8 Molecular Biology Department, Genentech Inc., South San Francisco, CA, 94080, USA. 9 Institute of Bioinformatics, Bangalore, Karnataka, 560066, India. 10 QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia. 11 Department of Pathology and Laboratory Medicine, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA. 12 SciGenom Labs, Cochin, Kerala, 682037, India. 13 Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, 08826, South Korea. 14 Research and Development Department, MedGenome Labs Pvt. Ltd., Bangalore, Karnataka, 560099, India. 15 Research and Development Department, MedGenome Inc, Foster City, CA, 94404, USA. 16 Department of Pathology, Cancer Hospital and Research Institute, Gwalior, Madhya Pradesh, 474009, India. 17 Department of Surgical Oncology, Cancer Hospital and Research Institute, Gwalior, Madhya Pradesh, 474009, India. 18 Jiwaji University, Gwalior, Madhya Pradesh, 474011, India. 19 Department of Pathology, Millennium Institute on Immunology and Immunotherapy, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. 20 Applied Molecular and Cellular Biology PhD Program Universidad De la Frontera, Temuco, Chile. 21 Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. 22 Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, 08826, South Korea. jangjy4@snu.ac.kr. 23 Molecular Biology Department, Genentech Inc., South San Francisco, CA, 94080, USA. sekar@sgrf.org. 24 SciGenom Research Foundation, 3rd Floor, Narayana Nethralaya Building, Narayana Health City, #258/A, Bommasandra, Hosur Road, Bangalore, Karnataka, 560099, India. sekar@sgrf.org.