Rapid Evolution of the CD8+ TCR Repertoire in Neonatal Mice

Alison J. Carey*,†, Donald T. Gracias†,1, Jillian L. Thayer†, Alina C. Boesteanu†,2,Ogan K. Kumova†, Yvonne M. Mueller†,‡, Jennifer L. Hope†,‡, Joseph A. Fraietta§,David B. H. van Zessen‡,¶ and Peter D. Katsikis†,‡ *Pediatrics, Drexel University College of Medicine, Philadelphia, PA 19102; †Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19102; ‡Immunology, Erasmus University Medical Center, 015 N Rotterdam, the Netherlands; §Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA 19104; and ¶Bioinformatics, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands