Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis

P. Savola1,2, T. Kelkka1,2, H.L. Rajala1, A. Kuuliala3, K. Kuuliala3, S. Eldfors4, P. Ellonen4, S. Lagstrom4, M. Lepisto4, T. Hannunen4, E.I. Andersson1, R.K. Khajuria1, T. Jaatinen5, R. Koivuniemi6, H. Repo3, J. Saarela4, K. Porkka1, M. Leirisalo-Repo6, & S. Mustjoki1,2 1Hematology Research Unit Helsinki, University of Helsinki and Department of Hematology, Helsinki University Hospital Comprehensive Cancer Centre, Haartmaninkatu 8, FIN-00290 Helsinki, Finland. 2Department of Clinical Chemistry and Hematology, University of Helsinki, Haartmaninkatu 8, FIN-00290 Helsinki, Finland. 3Bacteriology and Immunology, Medicum, University of Helsinki, Haartmaninkatu 3, FIN-00290 Helsinki, Finland. 4Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Tukholmankatu 8, FIN-00290 Helsinki, Finland. 5Histocompatibility Testing Laboratory, Finnish Red Cross Blood Service, Kivihaantie 7, FIN-00310 Helsinki, Finland. 6Department of Rheumatology, University of Helsinki and Helsinki University Hospital, Haartmaninkatu 4, FIN-00290 Helsinki, Finland.