T cell repertoire analysis suggest a prominent bystander response in human cardiac allograft vasculopathy

Marlena V Habal 1,2, April M I Miller 1,3, Samhita Rao 1, Sijie Lin 1,4, Aleksandar Obradovic 1, Mohsen Khosravi-Maharlooei 1, Sarah See 1, Poulomi Roy 1, Shihab Ronzon 1, Siu-Hong Ho 1,5, Charles Marboe 6, Yoshifumi Naka 7, Koji Takeda 7, Susan Restaino 2, Arnold Han 1, Donna Mancini 8, Michael Givertz 9, Joren C Madsen 10,11, Megan Sykes 1, Linda Addonizio 12, Maryjane Farr 2, Emmanuel Zorn 1; 1 Columbia Center for Translational Immunology, Columbia University Irving Medical Center, New York, NY, USA. 2 Department of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, USA. 3 Case Western Reserve University School of Medicine, NY, USA. 4 Stanford University, Department of Genetics, NY, USA. 5 Cytek Biosciences, NY, USA. 6 Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA. 7 Department of Surgery, Division of Cardiothoracic Surgery, Columbia University Irving Medical Center, New York, NY, USA. 8 Department of Medicine, Mount Sinai Hospital, Icahn School of Medicine, New York, NY, USA. 9 Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. 10 Center for Transplantation Science, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. 11 Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. 12 Department of Pediatrics, Division of Pediatric Cardiology, Columbia University Irving Medical Center, New York, NY, USA.