T Cell Repertoire in Combination with T cell Density Predicts Clinical Outcomes in Patients with Merkel Cell Carcinoma

Maya Farah1,*, Alexandre Reuben2,*, Ivelina Spassova3, Richard K. Yang1, Linda Kubat3, Priyadharsini Nagarajan1, Jing Ning4, Wen Li4, Phyu P. Aung1, Jonathan L. Curry1,5,6, Carlos A. Torres-Cabala1,5, Courtney W. Hudgens6, Selma Ugurel7, Dirk Schadendorf7, Curtis Gumbs8, Latasha D. Little8, Andrew Futreal8, Ignacio I. Wistuba6, Victor G. Prieto1,5, Linghua Wang8, Michael K. Wong9, Jennifer A. Wargo8,10, Jürgen C. Becker3,7,11,, and Michael T. Tetzlaff1,6,; The University of Texas MD Anderson Cancer Center 1 Department of Pathology and Laboratory Medicine 2 Department of Thoracic/Head & Neck Medical Oncology 3Translational Skin Cancer Research, University Clinic Essen, Germany 4 Department of Biostatistics 5 Department of Dermatology 6 Department of Translational and Molecular Pathology 7 Department of Dermatology, University Clinic Essen, Germany 8 Department of Genomic Medicine 9 Department of Melanoma Medical Oncology 10Department of Surgical Oncology 11German Cancer Consortium (DKTK), German Cancer Center (DKFZ), Heidelberg, Germany