TCR ITAM multiplicity is required for the generation of follicular helper T-cells

Hwang S1, Palin AC1, Li L1, Song KD1, Lee J1, Herz J2, Tubo N3, Chu H3, Pepper M3, Lesourne R1, Zvezdova E1, Pinkhasov J1, Jenkins MK3, McGavern D2, Love PE1. 1Program in Genomics of Differentiation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Room 2B-210, Building 6B, Bethesda, Maryland 20892, USA. 2Viral Immunology and Intravital Imaging Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA. 3Department of Microbiology, Center for Immunology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA.