Ultra-efficient sequencing of T Cell receptor repertoires reveals shared responses in muscle from patients with Myositis

Janelle M Montagne 1, Xuwen Alice Zheng 1, Iago Pinal-Fernandez 2, Jose C Milisenda 3, Lisa Christopher-Stine 4, Thomas E Lloyd 5, Andrew L Mammen 2, H Benjamin Larman 6; 1 Division of Immunology, Pathology Department, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. 2 Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Regulations, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. 3 Internal Medicine Department, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain and Centro de Investigación Médica en Red Enfermedades Raras. 4 Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. 5 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. 6 Division of Immunology, Pathology Department, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: hlarman1@jhmi.edu.