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Lack of association between pandemic chilblains and SARS-CoV-2 infection

Gehlhausen JR, et al.
PNAS
March 2022
Authors and Affiliates
Jeff R Gehlhausen 1, Alicia J Little 1, Christine J Ko 1,2, Marc Emmenegger 3, Carolina Lucas 4, Patrick Wong 4, Jon Klein 4, Peiwen Lu 4, Tianyang Mao 4, Jillian Jaycox 4, Eric Wang 4, Yale IMPACT Team; Nelson Ugwu 1, Cate Muenker 5, Dilgash Mekael 1, Rhonda Q Klein 1,6, Robert Patrignelli 7, Richard Antaya 1, Jennifer McNiff 1,2, William Damsky 1,2, Kathy Kamath 8, John Shon 8, Aaron M Ring 4, Inci Yildirim 5,9,10, Saad Omer 5,9,11, Albert I Ko 5,11, Adriano Aguzzi 3, Akiko Iwasaki 12,4,13,14; 1 Yale Department of Dermatology, Yale University, New Haven, CT 06510. 2 Yale Department of Pathology, Yale University, New Haven, CT 06510. 3 Institute of Neuropathology, University Hospital of Zürich, 8091 Zürich, Switzerland. 4 Yale Department of Immunobiology, Yale University, New Haven, CT 06510. 5 Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510. 6 Modern Dermatology, Westport, CT 06880. 7 Patrignelli Dermatology Private Practice, Trumbull, CT 06611. 8 Serimmune, Inc., Santa Barbara, CA 93117. 9 Yale Institute for Global Health, Yale University, New Haven, CT 06510. 10 Department of Pediatrics, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06510. 11 Yale Department Medicine, Section of Infectious Diseases, Yale University, New Haven, CT 06510. 12 Yale Department of Dermatology, Yale University, New Haven, CT 06510; akiko.iwasaki@yale.edu. 13 Department of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06510. 14 HHMI, Chevy Chase, MD 20815.

Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

Sacco K, et al.
Nature Medicine
February 2022
Authors and Affiliates
Keith Sacco #,1, Riccardo Castagnoli #,1,2, Svetlana Vakkilainen #,1, Can Liu #,3,4, Ottavia M Delmonte 1, Cihan Oguz 5,6, Ian M Kaplan 7, Sara Alehashemi 1, Peter D Burbelo 8, Farzana Bhuyan 1, Adriana A de Jesus 1, Kerry Dobbs 1, Lindsey B Rosen 1, Aristine Cheng 1, Elana Shaw 1, Mikko S Vakkilainen 9, Francesca Pala 1, Justin Lack 3,5, Yu Zhang 1, Danielle L Fink 10, Vasileios Oikonomou 1, Andrew L Snow 11, Clifton L Dalgard 12,13, Jinguo Chen 14, Brian A Sellers 14, Gina A Montealegre Sanchez 15, Karyl Barron 16, Emma Rey-Jurado 17, Cecilia Vial 17, Maria Cecilia Poli 17,18, Amelia Licari 2, Daniela Montagna 2,19, Gian Luigi Marseglia 2, Francesco Licciardi 20, Ugo Ramenghi 20, Valentina Discepolo 21, Andrea Lo Vecchio 21, Alfredo Guarino 21, Eli M Eisenstein 22, Luisa Imberti 23, Alessandra Sottini 23, Andrea Biondi 24, Sayonara Mató 25, Dana Gerstbacher 26, Meng Truong 1, Michael A Stack 1, Mary Magliocco 27, Marita Bosticardo 1, Tomoki Kawai 1, Jeffrey J Danielson 1, Tyler Hulett 28, Manor Askenazi 28, Shaohui Hu 28, NIAID Immune Response to COVID Group; Chile MIS-C Group; Pavia Pediatric COVID-19 Group; Jeffrey I Cohen 29, Helen C Su 1, Douglas B Kuhns 10, Michail S Lionakis 1, Thomas M Snyder 7, Steven M Holland 1, Raphaela Goldbach-Mansky 1, John S Tsang 3 30, Luigi D Notarangelo 31; 1 Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. 2 Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy. 3 Multiscale Systems Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. 4 Graduate Program in Biological Sciences, University of Maryland, College Park, MD, USA. 5 NIAID Collaborative Bioinformatics Resource (NCBR), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. 6 Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc, Frederick, MD, USA. 7 Adaptive Biotechnologies, Seattle, WA, USA. 8 National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA. 9 Department of Computer Science, Aalto University, Helsinki, Finland. 10 Applied/Developmental Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA. 11 Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. 12 Department of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. 13 The American Genome Center, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. 14 Trans-NIH Center for Human Immunology, Autoimmunity, and Inflammation (CHI), National Institutes of Health, Bethesda, MD, USA. 15 Intramural Clinical Management and Operation Branch (ICMOB), Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. 16 Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. 17 Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile. 18 Unidad de Inmunología y Reumatología, Hospital de niños Dr. Roberto del Río, Santiago, Chile. 19 Laboratory of Immunology and Transplantation, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. 20 Department of Pediatric and Public Health Sciences, Regina Margherita Children's Hospital, A.O.U. Città Della Salute E Della Scienza Di Torino, University of Turin, Turin, Italy. 21 Department of Translational Medical Sciences, Section of Pediatrics, University of Naples Federico II, Napoli, Italy. 22 Department of Pediatrics, Hadassah-Hebrew University Medical Center, Mount Scopus, Jerusalem, Israel. 23 CREA Laboratory (AIL Center for Hemato-Oncologic Research), Diagnostic Department, ASST Spedali Civili di Brescia, Brescia, Italy. 24 Pediatric Department and Centro Tettamanti-European Reference Network PaedCan, EuroBloodNet, MetabERN, University of Milano Bicocca, Fondazione MBBM, Ospedale San Gerardo, Monza, Italy. 25 Randall Children's Hospital at Legacy Emanuel, Portland, OR, USA. 26 Division of Pediatric Rheumatology, Stanford Children's Hospital, Stanford, CA, USA. 27 Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. 28 CDI Laboratories, Antygen Division, Baltimore, MD, USA. 29 Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. 30 NIH Center for Human Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. 31 Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. luigi.notarangelo2@nih.gov. # Contributed equally.

Evidence of SARS-CoV-2-Specific T-Cell-Mediated Myocarditis in a MIS-A Case

Vannelle KM, et al.
Frontiers in Immunology
February 2022
Authors and Affiliates
Kevin M Vannella 1,2, Cihan Oguz 3,4, Sydney R Stein 1,2, Stefania Pittaluga 5, Esra Dikoglu 5, Arjun Kanwal 6, Sabrina C Ramelli 7, Thomas Briese 8, Ling Su 9, Xiaolin Wu 9, Marcos J Ramos-Benitez 1,2,10, Luis J Perez-Valencia 1,2, Ashley Babyak 1,2, Nu Ri Cha 11, Joon-Yong Chung 5, Kris Ylaya 5, Ronson J Madathil 12, Kapil K Saharia 13, Thomas M Scalea 14, Quincy K Tran 15, Daniel L Herr 16, David E Kleiner 5, Stephen M Hewitt 5, Luigi D Notarangelo 17, Alison Grazioli 18, Daniel S Chertow 1,2; 1 Emerging Pathogens Section, Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, United States. 2 Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States. 3 National Institute of Allergy and Infectious Diseases Collaborative Bioinformatics Resource, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, United States. 4 Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, United States. 5 Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States. 6 Division of Cardiology, Westchester Medical Center, Valhalla, NY, United States. 7 Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, United States. 8 Center for Infection and Immunity, Columbia University Mailman School of Public Health, New York, NY, United States. 9 Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, United States. 10 Postdoctoral Research Associate Training Program, National Institute of General Medical Sciences, National Institutes of Health, Bethesda, MD, United States. 11 Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, United States. 12 Department of Surgery, Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD, United States. 13 Department of Medicine, Division of Infectious Disease, University of Maryland School of Medicine, Baltimore, MD, United States. 14 Department of Surgery, Program in Trauma, R. Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD, United States. 15 Department of Emergency Medicine, R. Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD, United States. 16 Department of Medicine, Program in Trauma, R. Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD, United States. 17 Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States. 18 Kidney Diseases Branch, Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.

Activation and expansion of T-follicular helper cells in chronic lymphocytic leukemia nurselike cell co-cultures

Vaca AM, et al.
February 2022
Authors and Affiliates
Alicia M Vaca 1, Nikolaos Ioannou 2, Mariela Sivina 1, Elisavet Vlachonikola 3, Karen Clise-Dwyer 4, Ekaterina Kim 1, Dan Li 4, Qing Ma 4, Alessandra Ferrajoli 1, Zeev Estrov 1, William G Wierda 1, Piers E M Patten 2, Alan G Ramsay 2, Jan A Burger 5; 1 Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. 2 School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, UK. 3 Institute of Applied Biosciences, Center for Research and Technology Hellas, Thessaloniki, Greece. 4 Department of Stem Cell Transplantation and Hematopoietic Biology & Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. 5 Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. jaburger@mdanderson.org.

Randomized Mechlorethamine/Chlormethine Induced Dermatitis Assessment Study (MIDAS) Establishes Benefit of Topical Triamcinolone 0.1% Ointment Cotreatment in Mycosis Fungoides

Alexander-Savino CV, et al.
February 2022
Authors and Affiliates
Carolina V Alexander-Savino 1, Catherine G Chung 2, Elaine S Gilmore 1, Sean M Carroll 1, Brian Poligone 3,4; 1 Rochester Skin Lymphoma Medical Group, 6800 Pittsford Palmyra Rd, Suite 150, Fairport, NY, 14450, USA. 2 Dermatology and Pathology, The Ohio State University, Columbus, OH, 43210, USA. 3 Rochester Skin Lymphoma Medical Group, 6800 Pittsford Palmyra Rd, Suite 150, Fairport, NY, 14450, USA. bpoligone@roclymphoma.com. 4 Rochester General Hospital Research Institute, Rochester, NY, 14621, USA. bpoligone@roclymphoma.com.

Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes

Shah P, et al.
Journal for ImmunoTherapy of Cancer
February 2022
Authors and Affiliates
Parin Shah #,1, Marie-Andrée Forget #,1,2, Meredith L Frank #,3, Peixin Jiang 3, Donastas Sakellariou-Thompson 2, Lorenzo Federico 1, Roohussaba Khairullah 3, Chantal Alexia Neutzler 2, Ignacio Wistuba 3,4, Chi-Wan B Chow 4, Yan Long 4, Junya Fujimoto 4, Shiaw-Yih Lin 5, Anirban Maitra 4, Marcelo V Negrao 3, Kyle Gregory Mitchell 6, Annikka Weissferdt 7, Ara A Vaporciyan 6, Tina Cascone 3, Jack A Roth 6, Jianjun Zhang 3, Boris Sepesi 6, Don L Gibbons 3, John V Heymach 3, Cara L Haymaker 4, Daniel J McGrail 8, Alexandre Reuben 9, Chantale Bernatchez 10,2; 1 Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 2 Biologics Development, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 3 Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 4 Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 5 Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 6 Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 7 Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. 8 Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA cbernatchez@mdanderson.org AReuben@mdanderson.org djmcgrail@mdanderson.org. 9 Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA cbernatchez@mdanderson.org AReuben@mdanderson.org djmcgrail@mdanderson.org. 10 Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA cbernatchez@mdanderson.org AReuben@mdanderson.org djmcgrail@mdanderson.org. # Contributed equally.

Multiple early factors anticipate post-acute COVID-19 sequelae

Su Y, et al.
Cell
February 2022
Authors and Affiliates
Yapeng Su 1, Dan Yuan 2, Daniel G Chen 3, Rachel H Ng 2, Kai Wang 4, Jongchan Choi 4, Sarah Li 4, Sunga Hong 4, Rongyu Zhang 2, Jingyi Xie 5, Sergey A Kornilov 4, Kelsey Scherler 4, Ana Jimena Pavlovitch-Bedzyk 6, Shen Dong 7, Christopher Lausted 4, Inyoul Lee 4, Shannon Fallen 4, Chengzhen L Dai 4, Priyanka Baloni 4, Brett Smith 4, Venkata R Duvvuri 4, Kristin G Anderson 8, Jing Li 6, Fan Yang 9, Caroline J Duncombe 10, Denise J McCulloch 11, Clifford Rostomily 4, Pamela Troisch 4, Jing Zhou 12, Sean Mackay 12, Quinn DeGottardi 13, Damon H May 13, Ruth Taniguchi 13, Rachel M Gittelman 13, Mark Klinger 13, Thomas M Snyder 13, Ryan Roper 4, Gladys Wojciechowska 14, Kim Murray 4, Rick Edmark 4, Simon Evans 4, Lesley Jones 4, Yong Zhou 4, Lee Rowen 4, Rachel Liu 4, William Chour 4, Heather A Algren 15, William R Berrington 15, Julie A Wallick 15, Rebecca A Cochran 15, Mary E Micikas 15, ISB-Swedish COVID-19 Biobanking Unit 4; Terri Wrin 16, Christos J Petropoulos 16, Hunter R Cole 17, Trevan D Fischer 17, Wei Wei 4, Dave S B Hoon 17, Nathan D Price 4, Naeha Subramanian 18, Joshua A Hill 19, Jennifer Hadlock 4, Andrew T Magis 4, Antoni Ribas 20, Lewis L Lanier 21, Scott D Boyd 9, Jeffrey A Bluestone 7, Helen Chu 22, Leroy Hood 23, Raphael Gottardo 24, Philip D Greenberg 8, Mark M Davis 25, Jason D Goldman 26, James R Heath 27; 1 Institute for Systems Biology, Seattle, WA 98109, USA; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Clinical Research Division, Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address: suyapeng.tju@gmail.com. 2 Institute for Systems Biology, Seattle, WA 98109, USA; Department of Bioengineering, University of Washington, Seattle, WA 98105, USA. 3 Institute for Systems Biology, Seattle, WA 98109, USA; Department of Microbiology and Department of Informatics, University of Washington, Seattle, WA 98195, USA. 4 Institute for Systems Biology, Seattle, WA 98109, USA. 5 Institute for Systems Biology, Seattle, WA 98109, USA; Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98105, USA. 6 Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA. 7 Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. 8 Clinical Research Division, Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Departments of Immunology and Medicine, University of Washington, Seattle, WA 98109, USA. 9 Department of Pathology, Stanford University, Stanford, CA 94304, USA. 10 Division of Global Health, University of Washington, Seattle, WA 98105, USA. 11 Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98109, USA. 12 Isoplexis Corporation, Branford, CT 06405, USA. 13 Adaptive Biotechnologies, Seattle, WA 98109, USA. 14 Institute for Systems Biology, Seattle, WA 98109, USA; Medical University of Białystok, Białystok 15089, Poland. 15 Swedish Center for Research and Innovation, Swedish Medical Center, Seattle, WA 98109, USA; Providence St. Joseph Health, Renton, WA 98057, USA. 16 Monogram Biosciences, South San Francisco, CA 94080, USA. 17 St. John's Cancer Institute at Saint John's Health Center, Santa Monica, CA 90404, USA. 18 Institute for Systems Biology, Seattle, WA 98109, USA; Department of Global Heath and Department of Immunology, University of Washington, Seattle, WA 98109, USA. 19 Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98109, USA. 20 Department of Medicine, University of California, Los Angeles, and Parker Institute for Cancer Immunotherapy, Los Angeles, CA 90095, USA. 21 Department of Microbiology and Immunology, University of California, San Francisco, and Parker Institute for Cancer Immunotherapy, San Francisco, CA 94143, USA. 22 Division of Global Health, University of Washington, Seattle, WA 98105, USA; Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98109, USA. 23 Institute for Systems Biology, Seattle, WA 98109, USA; Providence St. Joseph Health, Renton, WA 98057, USA. 24 Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Statistics, University of Washington, Seattle, WA 98195, USA; Biomedical Data Sciences, Lausanne University Hospital, University of Lausanne, Lausanne, 1011, Switzerland. 25 Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA; The Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. 26 Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98109, USA; Swedish Center for Research and Innovation, Swedish Medical Center, Seattle, WA 98109, USA; Providence St. Joseph Health, Renton, WA 98057, USA. Electronic address: jason.goldman@swedish.org. 27 Institute for Systems Biology, Seattle, WA 98109, USA; Department of Bioengineering, University of Washington, Seattle, WA 98105, USA. Electronic address: jim.heath@isbscience.org.

The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders

Pagliuca S, et al.
Blood
February 2022
Authors and Affiliates
Simona Pagliuca 1,2, Carmelo Gurnari 1,3, Hassan Awada 1, Ashwin Kishtagari 1, Sunisa Kongkiatkamon 1, Laila Terkawi 1, Misam Zawit 1, Yihong Guan 1, Thomas LaFramboise 4, Babal K Jha 1, Bhumika J Patel 5, Betty K Hamilton 6, Navneet S Majhail 6, Sofie Lundgren 7,8, Satu Mustjoki 7,8,9, Yogen Saunthararajah 1, Valeria Visconte 1, Timothy A Chan 10, Chao-Yie Yang 11, Tobias L Lenz 12,13, Jaroslaw P Maciejewski 1; 1 Translational Hematology and Oncology Research Department, Cleveland Clinic, Cleveland, OH. 2 University of Paris, Paris, France. 3 Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy. 4 Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH. 5 Leukemia Program, Department of Hematology and Oncology, Cleveland Clinic, Cleveland, OH. 6 Blood and Marrow Transplant Program, Department of Hematology and Oncology, Cleveland Clinic, Cleveland, OH. 7 Hematology Research Unit Helsinki, University of Helsinki-Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland. 8 Translational Immunology Research Program and Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland. 9 ICAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland. 10 Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH. 11 Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN. 12 Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön, Germany; and. 13 Research Unit for Evolutionary Immunogenomics, Department of Biology, University of Hamburg, Hamburg, Germany.

HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses

Buckely PR, et al.
immunology
February 2022
Authors and Affiliates
Paul R Buckley 1,2, Chloe H Lee 1,2, Mariana Pereira Pinho 1, Rosana Ottakandathil Babu 1,2, Jeongmin Woo 1,2, Agne Antanaviciute 1,2, Alison Simmons 1, Graham Ogg 1, Hashem Koohy 1,2; 1 MRC Human Immunology Unit, Medical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine (WIMM), John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom. 2 MRC WIMM Centre for Computational Biology, Medical Research Council (MRC) Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.

Early versus late response to daratumumab-based triplet therapies in patients with multiple myeloma: a pooled analysis of trials POLLUX, CASTOR and MAIA.

Wang J, et al.
Leukemia & Lymphoma
February 2022
Authors and Affiliates
Jiasheng Wanga , Raul Arroyo-Suarezb, Srilatha Dasarib, Kanithra Sekaranb and William Tsec aDepartment of Hematology and Oncology, Seidman Cancer Center, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; bDepartment of Internal Medicine, MetroHealth Medical Center, Cleveland, OH, USA; cDepartment of Hematology and Oncology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, USA
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