Cerebrospinal fluid immunoglobulin light chain ratios predict disease progression in multiple sclerosis

Emma Rathbone,1 Lindsay Durant,1 James Kinsella,1 Antony R Parker,2 Ghaniah Hassan-Smith,1 Michael R Douglas,3,4 S John Curnow5 1Centre for Translational Inflammation Research Institute of Inflammation and Ageing, College of Medical and Dental Sciences University of Birmingham, Birmingham, UK 2The Binding Site Group Ltd, Birmingham, UK 3Department of Neurology, Dudley Group NHS Foundation Trust, Russells Hall Hospital, Birmingham, UK 4School of Life and Health Sciences, Aston University, Birmingham, UK 5Centre for Translational Inflammation Research, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2WB, UK