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Rational design of anti-GITR-based combination immunotherapy

Zappasodi et al.
Nature Medicine
April 2019
Authors and Affiliates
Zappasodi R1,2, Sirard C3, Li Y1,2, Budhu S1, Abu-Akeel M1, Liu C1, Yang X1, Zhong H1, Newman W3, Qi J2,4, Wong P2,4, Schaer D1, Koon H5, Velcheti V6, Hellmann MD2,7,8, Postow MA7,8, Callahan MK2,7,8, Wolchok JD9,10,11,12, Merghoub T13,14,15; Author information 1 Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA. 2 Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA. 3 Leap Therapeutics, Cambridge, MA, USA. 4 Immune Monitoring Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA. 5 Case Western Reserve University, Cleveland, OH, USA. 6 Department of Hematology and Oncology, New York University School of Medicine, New York, NY, USA. 7 Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. 8 Weill Cornell Medical College, New York, NY, USA. 9 Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA. wolchokj@mskcc.org. 10 Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA. wolchokj@mskcc.org. 11 Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. wolchokj@mskcc.org. 12 Weill Cornell Medical College, New York, NY, USA. wolchokj@mskcc.org. 13 Ludwig Collaborative and Swim Across America Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, USA. merghout@mskcc.org. 14 Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA. merghout@mskcc.org. 15 Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. merghout@mskcc.org.