Browse our 650+ Publications​

Latest Publications

T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes

Gomez-Tourino et al.
Nature Communications
Papers
November 2017
Authors and Affiliates
Iria Gomez-Tourino1,2,3, Yogesh Kamra1, Roman Baptista1,2, Anna Lorenc1 & Mark Peakman1,2 1Department of Immunobiology, Faculty of Life Sciences & Medicine, King’s College London, 2nd Floor, Borough Wing, Guy’s Hospital, London SE1 9RT, UK. 2National Institute for Health Research, Biomedical Research Centre at Guy’s and St Thomas’ Hospital Foundation Trust and King’s College London, Guy’s Hospital, London SE1 9RT, UK. 3Present address: Immunology Laboratory, Biomedical Research Center (CINBIO), Centro Singular de Investigación de Galicia, University of Vigo, Campus Universitario de Vigo, Pontevedra 36310, Spain

T cell receptor sequencing of early-stage breast cancer tumors identifies altered clonal structure of the T cell repertoire

Beausang et al.
Proceedings of the National Academy of Sciences
November 2017
Authors and Affiliates
Beausang JF1, Wheeler AJ2, Chan NH2, Hanft VR2, Dirbas FM2, Jeffrey SS2, Quake SR3,4,5; 1 Department of Bioengineering, Stanford University, Stanford, CA 94305. 2 Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305. 3 Department of Bioengineering, Stanford University, Stanford, CA 94305; quake@stanford.edu. 4 Department of Applied Physics, Stanford University, Stanford, CA 94305. 5 Chan Zuckerberg Biohub, San Francisco, CA 94518.

T-cell Localization, Activation, and Clonal Expansion in Human Pancreatic Ductal Adenocarcinoma

Stromnes et al.
Cancer Immunology Research
October 2017
Authors and Affiliates
Stromnes IM1,2, Hulbert A3,2, Pierce RH3,2, Greenberg PD1,2,4, Hingorani SR1,4,5; 1 Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. ingunn@umn.edu pgreen@uw.edu srh@fhcrc.org. 2 Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, Washington. 3 Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. 4 Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington. 5 Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.

Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab

Reuben et al.
OncoImmunology
Papers
October 2017
Authors and Affiliates
Alexandre Reubena, Mariana Petaccia de Macedob, Jennifer McQuadec, Aron Joond, Zhiyong Rene,Tiffany Calderoneb, Brandy Connerb, Khalida Wanib, Zachary A. Coopera,f,z, Hussein Tawbic, Michael T. Tetzlaffb,e, Robert F. Paderag, Jean-Bernard Durandh, Alexander J. Lazarb,e, Jennifer A. Wargoa,f, and Michael A. Daviesb,c,i aDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; bTranslational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; cMelanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; dBiostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; ePathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; fGenomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; gDepartment of Pathology, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA, USA; hCardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; iSystems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

In Silico Prediction Analysis of Idiotope-Driven T–B Cell Collaboration in Multiple Sclerosis

Høglund et al.
Frontiers in Immunology
Papers
October 2017
Authors and Affiliates
Rune A. Høglund1,2, Andreas Lossius1,3, Jorunn N. Johansen3, Jane Homan4, Jūratė Šaltytė Benth2,5, Harlan Robins6, Bjarne Bogen2,3,7, Robert D. Bremel4 and Trygve Holmøy1,2 1Department of Neurology, Akershus University Hospital, Lørenskog, Norway, 2Institute of Clinical Medicine, University of Oslo, Oslo, Norway, 3Faculty of Medicine, Department of Immunology and Transfusion Medicine, University of Oslo and Oslo University Hospital Rikshospitalet, Oslo, Norway, 4EigenBio LLC, Madison, WI, United States, 5Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway, 6Adaptive Biotechnologies, Seattle, WA, United States, 7Centre for Immune Regulation, University of Oslo, Oslo, Norway

TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence

Reuben et al.
Cancer Discovery
Papers
October 2017
Authors and Affiliates
Alexandre Reuben1,2, Rachel Gittelman3, Jianjun Gao4, Jiexin Zhang5, Erik C. Yusko3, Chang-Jiun Wu2, Ryan Emerson3, Jianhua Zhang2, Christopher Tipton3, Jun Li2, Kelly Quek2,6, Vancheswaran Gopalakrishnan1, Runzhe Chen2,6, Luis M. Vence7, Tina Cascone6, Marissa Vignali3, Junya Fujimoto8, Jaime Rodriguez-Canales8, Edwin R. Parra8, Latasha D. Little2, Curtis Gumbs2, Marie-Andrée Forget9, Lorenzo Federico9, Cara Haymaker9, Carmen Behrens8, Sharon Benzeno3, Chantale Bernatchez9, Boris Sepesi10, Don L. Gibbons6, Jennifer A. Wargo1,2, William N. William Jr6, Stephen Swisher10, John V. Heymach6, Harlan Robins3,11, J. Jack Lee12, Padmanee Sharma4,7, James P. Allison7, P. Andrew Futreal2, Ignacio I. Wistuba8, and Jianjun Zhang2,6 1Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 2Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. 3Adaptive Biotechnologies, Seattle, Washington. 4Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 5Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 6Department of Thoracic/Head and Neck Medical Oncology, The Univer- sity of Texas MD Anderson Cancer Center, Houston, Texas. 7Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 8Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 9Department of Melanoma Medical Oncology, The University of Texas MD Ander- son Cancer Center, Houston, Texas. 10Department of Thoracic Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. 11Department of Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington. 12Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Adipose Tissue is Enriched for Activated and Late-differentiated CD8+ T cells, and Shows Distinct CD8+ Receptor Usage, Compared to Blood in HIV-infected Persons

Koethe et al.
Journal of Acquired Immune Deficiency Syndromes
Papers
October 2017
Authors and Affiliates
John R. Koethe, MD, MS1,2, Wyatt McDonnell, BS3,4, Arion Kennedy, PhD5, Chike O. Abana, BS3, Mark Pilkinton, MD, PhD1,2, Ian Setliff, BS3,4, Ivelin Georgiev, PhD3,4, Louise Barnett, BS1, Cindy C. Hager, BS1, Rita Smith, BS1, Spyros A. Kalams, MD1,3, Alyssa Hasty, PhD2,5, Simon Mallal, MBBS1,3 1Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, 2VA Tennessee Valley Healthcare System, Nashville Tennessee, 3Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, 4Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, Tennessee, 5Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee

Clinically resolved psoriatic lesions contain psoriasis- specific IL-17–producing αβ T cell clones

Matos et al.
Journal of Clinical Investigation
Papers
October 2017
Authors and Affiliates
Tiago R. Matos,1,2,3 John T. O’Malley,1 Elizabeth L. Lowry,1 David Hamm,4 Ilan R. Kirsch,4 Harlan S. Robins,4 Thomas S. Kupper,1 James G. Krueger,5 and Rachael A. Clark1 1Department of Dermatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA. 2Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal. 3Academic Medical Center, Department of Dermatology, University of Amsterdam, Amsterdam, The Netherlands. 4Adaptive Biotechnologies, Seattle, Washington, USA. 5Department of Dermatology, Rockefeller University, New York, New York, USA.

An intermediate level of CD161 expression defines a novel activated, inflammatory, and pathogenic subset of CD8+ T cells involved in multiple sclerosis

Nicol et al.
Journal of Autoimmunity
Papers
October 2017
Authors and Affiliates
Bryan Nicola, b, Marion Saloua, b, Isabel Vogela, c, Alexandra Garciaa, c, Emilie Dugasta, c, Jeremy Morillea, b, c, Stephanie Kilensa, Eric Charpentierd, Audrey Donnartd, Steven Nedellece, Marylene Jacq-Foucherf, Fabienne Le Freref, Sandrine Wiertlewskie, f, Arnaud Bourreilleg, h, Sophie Brouarda, c, Laure Michela, b, f, Laurent Davida, i, j, k, l, m, Pierre-Antoine Gourrauda, Nicolas Degauquea, c, Arnaud B. Nicota, b, c, Laureline Berthelota, b, c, David-Axel Laplauda, b, f, g aCentre de Recherche en Transplantation et Immunologie UMR1064, INSERM, Universite de Nantes, Nantes, France bFaculte de M edecine, Universite de Nantes, Nantes, France cInstitut de Transplantation Urologie Nephrologie (ITUN), CHU Nantes, Nantes, France dINSERM UMR1087, CNRS UMR6291, Universite de Nantes, l'institut du thorax, Nantes, F-44000, France eSFR François Bonamy, Cellular and Tissue Imaging Core Facility (MicroPICell), Nantes, France fService de Neurologie, CHU Nantes, Nantes, France gINSERM 015, Centre d’Investigation Clinique, Nantes, France hInstitut des Maladies de l'Appareil Digestif, CIC-04 Inserm, CHU Nantes, Nantes, France iINSERM UMS 016, SFR Francois Bonamy, iPSC Core Facility, Nantes, France jUMR CNRS 3556, Nantes, F-44000, France kUniversite de Nantes, Nantes, F-44000, France lCHU de Nantes, Nantes, F-44000, France mLabEx IGO “Immunotherapy, Graft, Oncology”, Nantes, France
Previous Next