Browse our 650+ Publications​

Latest Publications

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

Kordasti et al.
Blood
Papers
September 2016
Authors and Affiliates
Shahram Kordasti,1,2,* Benedetta Costantini,1,2,* Thomas Seidl,1,* Pilar Perez Abellan,2 Marc Martinez Llordella,3 Donal McLornan,2 Kirsten E. Diggins,4 Austin Kulasekararaj,2 Cinzia Benfatto,1 Xingmin Feng,5 Alexander Smith,1,2 Syed A. Mian,1 Rossella Melchiotti,6 Emanuele de Rinaldis,6 Richard Ellis,6 Nedyalko Petrov,6 Giovanni A. M. Povoleri,3 Sun Sook Chung,1 N. Shaun B. Thomas,1 Farzin Farzaneh,1 Jonathan M. Irish,4 Susanne Heck,6 Neal S. Young,5 Judith C. W. Marsh,1,2 and Ghulam J. Mufti1,2 1Department of Haematological Medicine, King’s College London, London, United Kingdom; 2Haematological Medicine, King’s College Hospital, London, United Kingdom; 3Division of Transplantation Immunology & Mucosal Biology, King’s College London, London, United Kingdom; 4Department of Cancer Biology, Vanderbilt University, Nashville, TN; 5Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD; and 6National Institute for Health Research Biomedical Research Centre, King’s College London, London, United Kingdom

Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease

Henriksen et al.
Journal of Hepatology
Papers
September 2016
Authors and Affiliates
Eva Kristine Klemsdal Henriksen1,2,3,4, Kristin Kaasen Jørgensen1,5, Fatemeh Kaveh3,4,6, Kristian Holm1,2,3,4, David Hamm7, Johanna Olweus3,8,9, Espen Melum1,2,3,10, Brian K. Chung1,4,13, Tor J. Eide4,11, Knut E.A. Lundin10,12, Kirsten Muri Boberg1,3,4,10, Tom H. Karlsen1,2,3,4,10,Gideon M. Hirschfield13, Evaggelia Liaskou13,⇑ 1Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway; 2Research Institute of Internal Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway; 3K.G. Jebsen Inflammation Research Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway; 4Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; 5Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway; 6Department of Medical Genetics, Oslo University Hospital Ullevål, Oslo, Norway; 7Adaptive Biotechnologies Corp., Seattle, WA, USA; 8Department of Cancer Immunology, Institute for Cancer Research,Oslo University Hospital Radiumhospitalet, Oslo, Norway; 9K.G. Jebsen Center for Cancer Immunotherapy, Institute of Clinical Medicine, University of Oslo, Oslo, Norway; 10Section of Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway; 11Department of Pathology, Oslo University Hospital Rikshospitalet, Oslo, Norway; 12Centre for Immune Regulation, Faculty of Medicine, University of Oslo, Oslo, Norway; 13Centre for Liver Research and NIHR Birmingham Biomedical Research Unit, Institute of Biomedical Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK

Augmentation of cellular and humoral immune responses to HPV16 and HPV18 E6 and E7 antigens by VGX-3100

Morrow et al.
Molecular Therapy — Oncolytics
Papers
September 2016
Authors and Affiliates
Matthew P Morrow1, Kimberly A Kraynyak1, Albert J Sylvester1, Xuefei Shen1, Dinah Amante1, Lindsay Sakata1, Lamar Parker2, Jian Yan1, Jean Boyer1, Christian Roh1, Laurent Humeau1, Amir S Khan1, Kate Broderick1, Kathleen Marcozzi-Pierce1, Mary Giear1, Jessica Lee1, Cornelia L Trimble3, J Joseph Kim1, Niranjan Y Sardesai1, David B Weiner4 and Mark L Bagarazzi1 1 Inovio Pharmaceuticals, Plymouth Meeting, Pennsylvania, USA; 2 Unified Women’s Clinical Research, Winston-Salem, North Carolina, USA; 3 Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 4 The Wistar Institute, Philadelphia, Pennsylvania, USA

Chemotherapy and radiation therapy elicits tumor specific T cell responses in a breast cancer patient

Bernal-Estéve et al.
BMC Cancer
Papers
August 2016
Authors and Affiliates
David Bernal-Estévez 1,2 , Ramiro Sánchez 3 , Rafael E. Tejada 4 and Carlos Parra-López 1,5 1Immunology and Traslational Medicine Research Group, Graduated School in Biomedical Sciences, Department of Microbiology, Medical School, Universidad Nacional de Colombia, Carrera 30 #45-03 Building 471, office 304, Bogotá, Colombia South-America. 2Immunology and Clinical Oncology Bernal-Estévez et al. BMC Cancer (2016) 16:591 Page 12 of 13 Research Group (GIIOC), Fundación Salud de los Andes, Calle 44 No. 58-05, Bogotá, Colombia South-America. 3Clínica del Seno, Carrera 11 # 68-36, Bogotá, Colombia South-America. 4Hospital Occidente de Kennedy E.S.E., Servicio de Oncología, Bogotá, Colombia South-America. 5 Facultad de Medicina, Departamento de Microbiología, Universidad Nacional de Colombia, Carrera 30 Calle 45, Bogotá, Colombia.

Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency

Wong et al.
Papers
The Journal of Immunology
August 2016
Authors and Affiliates
Gabriel K. Wong,1,2 David Millar,3,4 Sarah Penny,1 James M. Heather,5 Punam Mistry,1 Nico Buettner,1 Jane Bryon,6 Aarnoud P. Huissoon,2 and Mark Cobbold3,4 1Medical Research Council Centre for Immune Regulation, University of Birmingham, Edgbaston B15 2TT, United Kingdom; 2West Midlands Primary Immunodeficiency Centre, Birmingham Heartlands Hospital, Birmingham B9 5SS, United Kingdom; 3Cancer Center, Massachusetts General Hospital, Boston MA 02114; 4Department of Medicine, Harvard Medical School, Charlestown, MA 02129; 5Division of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom; and 6Regional Genetics Laboratory, Birmingham Women’s Hospital, Birmingham B15 2TG, United Kingdom

A Public Database of Memory and Naive B- Cell Receptor Sequences

DeWitt et al.
Papers
PLOS ONE
August 2016
Authors and Affiliates
William S. DeWitt1, Paul Linda2,3, Thomas M. Snyder1, Anna M. Sherwood1, Marissa Vignali1, Christopher S. Carlson2, Philip D. Greenberg2, Natalie Duerkopp2, Ryan O. Emerson1, Harlan S. Robins1,2 1Adaptive Biotechnologies, Seattle, United States of America, 2Fred Hutchinson Cancer Research Center, Seattle, United States of America, 3University of Washington, Seattle, United States of America

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

Meermeier et al.
Nature Communications
Papers
August 2016
Authors and Affiliates
Erin W. Meermeier1, Bruno F. Laugel2, Andrew K. Sewell2, Alexandra J. Corbett3, Jamie Rossjohn2,4,5, James McCluskey3, Melanie J. Harriff6,7, Tamera Franks7, Marielle C. Gold1,6,7 & David M. Lewinsohn1,6,7 1 Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97239 USA. 2 Institute of Infection and Immunity, HenryWellcome Research Institute, Cardiff University School of Medicine, Cardiff CF14 4XN, UK. 3 Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria 3010, Australia. 4 Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia. 5 ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria 3800, Australia. 6 Department of Pulmonary and Critical Care Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA. 7 Department of Research, VA Portland Health Care Center, Portland, Oregon 97239, USA

Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma

Wallin et al.
Nature Communications
Papers
August 2016
Authors and Affiliates
Jeffrey J. Wallin1, Johanna C. Bendell2, Roel Funke1, Mario Sznol3, Konstanty Korski4, Suzanne Jones2, Genevive Hernandez1, James Mier5, Xian He1, F. Stephen Hodi6, Mitchell Denker1, Vincent Leveque1, Marta Canamero4, Galina Babitski4, Hartmut Koeppen1, James Ziai1, Neeraj Sharma1, Fabien Gaire4, Daniel S. Chen1, Daniel Waterkamp1, Priti S. Hegde1 & David F. McDermott5 1 Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA. 2 GI Oncology Research, Drug Development Unit, Sarah Cannon Research Institute, 250 25th Avenue North, Suite 100, Nashville, Tennessee, 37203, USA. 3 Department of Internal Medicine and Melanoma Unit, Yale Cancer Center, New Haven, Connecticut 06511, USA. 4 Roche Diagnostics GmbH, Nonnenwald 2, 82377 Penzberg, Germany. 5 Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, Massachusets 02215, USA. 6 Dana-Farber/Brigham and Women’s Cancer Center, 450 Brookline Avenue, Boston, Massachusets 02215, USA.

Tumor- and neoantigen-reactive T-cell receptors can be identified based on their frequency in fresh tumor

Pasetto et al.
Cancer Immunology Research
Papers
July 2016
Authors and Affiliates
Anna Pasetto1 , Alena Gros1 , Paul F Robbins1 , Drew C Deniger1 , Todd D Prickett1 , Rodrigo Matus-Nicodemos2,3 , Daniel C Douek3 , Bryan Howie4 , Harlan Robins4,5 , Maria R Parkhurst1 , Jared Gartner1 , Katarzyna Trebska-McGowan1 , Jessica S Crystal1 , Steven A Rosenberg1 * 1Surgery Branch, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA, 2Immunology Laboratory, Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USA, 3Human Immunology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA, 4Adaptive Biotechnologies, Seattle, WA 98102, USA, 5Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Previous Next